5V35
Crystal structure of V71F mutant of the FKBP domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) complexed with S-farnesyl-L-cysteine methyl ester
Summary for 5V35
| Entry DOI | 10.2210/pdb5v35/pdb |
| Descriptor | Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1), FARNESYL (2 entities in total) |
| Functional Keywords | aipl1, fkbp, chaperone, pde6, photoreceptor, lca, isoprenyl, signaling protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 19581.52 |
| Authors | Yadav, R.P.,Gakhar, L.,Liping, Y.,Artemyev, N.O. (deposition date: 2017-03-06, release date: 2017-07-26, Last modification date: 2023-10-04) |
| Primary citation | Yadav, R.P.,Gakhar, L.,Yu, L.,Artemyev, N.O. Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness. Proc. Natl. Acad. Sci. U.S.A., 114:E6536-E6545, 2017 Cited by PubMed: 28739921DOI: 10.1073/pnas.1704782114 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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