2JT2
 
 | | Solution Structure of the Aquifex aeolicus LpxC- CHIR-090 complex | | Descriptor: | N-{(1S,2R)-2-hydroxy-1-[(hydroxyamino)carbonyl]propyl}-4-{[4-(morpholin-4-ylmethyl)phenyl]ethynyl}benzamide, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ZINC ION | | Authors: | Barb, A.W, Jiang, L, Raetz, C.R.H, Zhou, P. | | Deposit date: | 2007-07-18 | | Release date: | 2007-12-04 | | Last modified: | 2021-10-20 | | Method: | SOLUTION NMR | | Cite: | Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2KCK
 | | NMR solution structure of the Northeast Structural Genomics Consortium (NESG) target MrR121A | | Descriptor: | TPR repeat | | Authors: | Barb, A.W, Lee, H.-W, Wang, X, Lee, D, Jiang, M, Ciccosanti, C, Xiao, R, Nair, R, Everett, J.K, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Prestegard, J.H, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-12-22 | | Release date: | 2009-01-27 | | Last modified: | 2018-01-24 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of the Northeast Structural Genomics Target MrR121A
To be Published
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2LR2
 | | Designed IgG and lanthanide binding probe for solution NMR, MRI and luminescence microscopy | | Descriptor: | Immunoglobulin G-binding protein A | | Authors: | Barb, A.W, Ho, T.G, Prestegard, J.H. | | Deposit date: | 2012-03-21 | | Release date: | 2012-09-12 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Lanthanide binding and IgG affinity construct: Potential applications in solution NMR, MRI, and luminescence microscopy.
Protein Sci., 21, 2012
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2L3U
 | | Solution Structure of Domain IV from the YbbR family protein of Desulfitobacterium hafniense: Northeast Structural Genomics Consortium target DhR29A | | Descriptor: | YbbR family protein | | Authors: | Barb, A.W, Lee, H, Belote, R.L, Ciccosanti, C, Hamilton, K, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Prestegard, J.H, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-09-23 | | Release date: | 2010-10-06 | | Last modified: | 2012-02-22 | | Method: | SOLUTION NMR | | Cite: | Structures of domains I and IV from YbbR are representative of a widely distributed protein family.
Protein Sci., 20, 2011
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5VCB
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5VBX
 | | Crystal structure of holo-[acyl-carrier-protein] synthase (AcpS) from Escherichia coli | | Descriptor: | 1,2-ETHANEDIOL, Holo-[acyl-carrier-protein] synthase, SODIUM ION | | Authors: | Marcella, A.M, Barb, A.W. | | Deposit date: | 2017-03-30 | | Release date: | 2017-11-01 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structure, High Affinity, and Negative Cooperativity of the Escherichia coli Holo-(Acyl Carrier Protein):Holo-(Acyl Carrier Protein) Synthase Complex.
J. Mol. Biol., 429, 2017
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5VU0
 | | Crystal structure of the complex between afucosylated/galactosylated human IgG1 Fc and Fc gamma receptor IIIa (CD16A) with Man5 N-glycans | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Subedi, G.S, Marcella, A.M, Barb, A.W. | | Deposit date: | 2017-05-18 | | Release date: | 2018-05-23 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Antibody Fucosylation Lowers the Fc gamma RIIIa/CD16a Affinity by Limiting the Conformations Sampled by the N162-Glycan.
ACS Chem. Biol., 13, 2018
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4KU1
 | | Role of the hinge and C-gamma-2/C-gamma-3 interface in immunoglobin G1 Fc domain motions: implications for Fc engineering | | Descriptor: | Ig gamma-1 chain C region, TETRAETHYLENE GLYCOL, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Frank, M, Walker, R, Lanzilotta, W.N, Prestegard, J.H, Barb, A.W. | | Deposit date: | 2013-05-21 | | Release date: | 2014-02-19 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Immunoglobulin g1 fc domain motions: implications for fc engineering.
J.Mol.Biol., 426, 2014
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6EAQ
 | | Glycosylated FCGR3B / CD16b in complex with afucosylated IgG1 Fc | | Descriptor: | Immunoglobulin gamma-1 heavy chain, Low affinity immunoglobulin gamma Fc region receptor III-B, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Roberts, J.T, Barb, A.W. | | Deposit date: | 2018-08-03 | | Release date: | 2018-11-07 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | A single amino acid distorts the Fc gamma receptor IIIb/CD16b structure upon binding immunoglobulin G1 and reduces affinity relative to CD16a.
J. Biol. Chem., 293, 2018
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2L5N
 | | NMR Structure of YbbR family protein Dhaf_0833 (residues 32-118) from Desulfitobacterium hafniense DCB-2: Northeast Structural Genomics Consortium target DhR29B | | Descriptor: | YbbR family protein | | Authors: | Cort, J.R, Barb, A.W, Lee, H, Ramelot, T.A, Yang, Y, Belote, R.L, Ciccosanti, C.R, Haleema, J, Acton, T.B, Xiao, R.R, Everett, J.K, Montelione, G.T, Prestegard, J.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-11-02 | | Release date: | 2010-12-29 | | Last modified: | 2012-02-22 | | Method: | SOLUTION NMR | | Cite: | Structures of domains I and IV from YbbR are representative of a widely distributed protein family.
Protein Sci., 20, 2011
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