PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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8QD2	Ayg1p in complex with 1,3-Dihydroxynaphthalene 分子名称: Pigment biosynthesis protein yellowish-green 1, naphthalene-1,3-diol 著者 Schmalhofer, M, Vagstad, A.L, Zhou, Q, Bode, H.B, Groll, M. 登録日 2023-08-28 公開日 2024-03-13 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Polyketide Trimming Shapes Dihydroxynaphthalene-Melanin and Anthraquinone Pigments. Adv Sci, 11, 2024
6NLW	The crystal structure of class D carbapenem-hydrolyzing beta-lactamase BlaA from Shewanella oneidensis MR-1 分子名称: Beta-lactamase, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Tan, K, Tesar, C, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2019-01-09 公開日 2019-01-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The crystal structure of class D carbapenem-hydrolyzing beta-lactamase BlaA from Shewanella oneidensis MR-1 To Be Published
8QF3	1.25-A structure of anti-Arc nanobody H11 分子名称: Nanobody H11 著者 Godoy Munoz, J.M, Kursula, P. 登録日 2023-09-02 公開日 2024-03-13 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 1.25-A structure of anti-Arc nanobody H11 To Be Published
5MP6	Structure of the Unliganded Fab from HIV-1 Neutralizing Antibody CAP248-2B that Binds to the gp120 C-terminus - gp41 Interface, at two Angstrom resolution. 分子名称: CAP248-2B Heavy Chain, CAP248-2B Light Chain, SULFATE ION 著者 Wibmer, C.K, Gorman, J, Kwong, P.D. 登録日 2016-12-15 公開日 2016-12-28 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.959 Å) 主引用文献 Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape. PLoS Pathog., 13, 2017
8SWU	Structure of Clostridium perfringens PNP bound to transition state analog IMMUCILLIN H and sulfate 分子名称: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, Purine nucleoside phosphorylase, SULFATE ION 著者 Fedorov, E, Ghosh, A. 登録日 2023-05-19 公開日 2023-10-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Phosphate Binding in PNP Alters Transition-State Analogue Affinity and Subunit Cooperativity. Biochemistry, 62, 2023
8VX0	CRYSTAL STRUCTURE OF CYP2C9*14 IN COMPLEX WITH LOSARTAN 分子名称: Cytochrome P450 2C9, PHOSPHATE ION, POTASSIUM ION, ... 著者 Shah, M.B. 登録日 2024-02-02 公開日 2024-06-12 最終更新日 2024-06-26 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Structural and biophysical analysis of cytochrome P450 2C9*14 and *27 variants in complex with losartan. J.Inorg.Biochem., 258, 2024
8VZ7	Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan 分子名称: Cytochrome P450 2C9, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Shah, M.B. 登録日 2024-02-11 公開日 2024-06-12 最終更新日 2024-06-26 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Structural and biophysical analysis of cytochrome P450 2C9*14 and *27 variants in complex with losartan. J.Inorg.Biochem., 258, 2024
6NRU	Crystal Structure of the Alpha-ribazole Phosphatase from Shigella flexneri 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CobC, ... 著者 Kim, Y, Gu, M, Shatsman, S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2019-01-24 公開日 2019-03-06 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.505 Å) 主引用文献 Crystal Structure of the Alpha-ribazole Phosphatase from Shigella flexneri To Be Published
7M8T	Crystal Structure of HLA-A*11:01 in complex with NSASFSTFK, an 9-mer epitope from SARS-CoV-2 spike (S370-378) 分子名称: Beta-2-microglobulin, CALCIUM ION, CHLORIDE ION, ... 著者 Gras, S, Nguyen, A.T, Szeto, C. 登録日 2021-03-30 公開日 2021-06-23 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 SARS-CoV-2 Spike-Derived Peptides Presented by HLA Molecules Biophysica, 1, 2021
5K9J	Crystal structure of multidonor HV6-1-class broadly neutralizing Influenza A antibody 56.a.09 isolated following H5 immunization. 分子名称: 56.a.09 heavy chain, 56.a.09 light chain, POLYETHYLENE GLYCOL (N=34) 著者 Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D. 登録日 2016-05-31 公開日 2016-07-27 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.904 Å) 主引用文献 Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses. Cell, 166, 2016
6VP5	Ethylene forming enzyme (EFE) D191E variant in complex with Fe(II), L-arginine, and 2OG 分子名称: 2-OXOGLUTARIC ACID, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ... 著者 Davis, K.M, Copeland, R.A, Boal, A.K. 登録日 2020-02-01 公開日 2021-02-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 An Iron(IV)-Oxo Intermediate Initiating l-Arginine Oxidation but Not Ethylene Production by the 2-Oxoglutarate-Dependent Oxygenase, Ethylene-Forming Enzyme. J.Am.Chem.Soc., 143, 2021
5MQE	Crystal structure of CREBBP bromodomain complexed with CBP006 分子名称: 4-bromanyl-~{N}-methyl-1~{H}-pyrrole-2-carboxamide, CREB-binding protein 著者 Zhu, J, Spiliotopoulos, D, Caflisch, A. 登録日 2016-12-20 公開日 2017-04-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain. Bioorg. Med. Chem. Lett., 27, 2017
5MMG	Crystal structure of CREBBP bromodomain complexed with UT07C 分子名称: 1-[4-ethoxy-3-[(1-methylsulfonylindol-6-yl)amino]phenyl]ethanone, CREB-binding protein 著者 Zhu, J, Caflisch, A. 登録日 2016-12-09 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules. ACS Med Chem Lett, 9, 2018
6H7R	Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/A198L variant 分子名称: 1,2-ETHANEDIOL, 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase, GLYCEROL 著者 Crennell, S.J, Danson, M.J, Royer, S. 登録日 2018-07-31 公開日 2019-08-14 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/A198L variant To Be Published
4X4L	Structure of human ALDH1A1 with inhibitor CM037 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CHLORIDE ION, Retinal dehydrogenase 1, ... 著者 Morgan, C.A, Hurley, T.D. 登録日 2014-12-03 公開日 2015-02-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Characterization of Two Distinct Structural Classes of Selective Aldehyde Dehydrogenase 1A1 Inhibitors. J.Med.Chem., 58, 2015
5MVR	Crystal structure of Bacillus subtilus YdiB 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Jault, J.-M, Aghajari, N. 登録日 2017-01-17 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.762 Å) 主引用文献 Expanding the Kinome World: A New Protein Kinase Family Widely Conserved in Bacteria. J. Mol. Biol., 429, 2017
8QOO	Crystal structure of human Sirt2 in complex with the peptide-based pseudo-inhibitor TNFn-4.1 分子名称: (2S,3R)-3-dodecylsulfanyl-2-methyl-butanoic acid, (2S,3S)-3-dodecylsulfanyl-2-methyl-butanoic acid, (R,R)-2,3-BUTANEDIOL, ... 著者 Friedrich, F, Kalbas, D, Meleshin, M, Einsle, O, Schutkowski, M, Jung, M. 登録日 2023-09-29 公開日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Development of potent TNFa-Myr-based pseudo-inhibitors for Sirtuin 2 To Be Published
6NS0	Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis complexed with L-lysine and Cladosporin 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-01-24 公開日 2019-02-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis with complexed with L-lysine and Cladosporin to be published
6QAP	Structure of the human aldehyde dehydrogenase 9A1 in C2 space group 分子名称: 1,2-ETHANEDIOL, 4-trimethylaminobutyraldehyde dehydrogenase, DI(HYDROXYETHYL)ETHER, ... 著者 Morera, S, Vigouroux, A. 登録日 2018-12-19 公開日 2019-04-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Kinetic and structural analysis of human ALDH9A1. Biosci.Rep., 39, 2019
8K4H	Crystal structure of PDE4D complexed with benzbromarone 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, ZINC ION, ... 著者 Liu, J.Y, Li, M.J, Xu, Y.C. 登録日 2023-07-18 公開日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors. Eur.J.Med.Chem., 262, 2023
8K4C	Crystal structure of PDE4D complexed with ethaverine hydrochloride 分子名称: 1,2-ETHANEDIOL, 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-isoquinoline, MAGNESIUM ION, ... 著者 Liu, J.Y, Li, M.J, Xu, Y.C. 登録日 2023-07-17 公開日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors. Eur.J.Med.Chem., 262, 2023
6YNE	GAPDH purified from the supernatant of HEK293F cells: crystal form 2 of 4. 分子名称: 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, Glyceraldehyde-3-phosphate dehydrogenase 著者 Roversi, P, Lia, A. 登録日 2020-04-13 公開日 2020-05-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.853 Å) 主引用文献 Partial catalytic Cys oxidation of human GAPDH to Cys-sulfonic acid. Wellcome Open Res, 5, 2020
5GWM	Solution structure of heterodimeric coiled-coil domain of Drosophila GABAB receptor 1 and 3 分子名称: Metabotropic GABA-B receptor subtype 1, Metabotropic GABA-B receptor subtype 3, isoform A 著者 Liu, X, Zhang, S, Zhang, C.X, Liu, J. 登録日 2016-09-12 公開日 2017-09-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structure of heterodimeric coiled-coil domain of Drosophila GABAB receptor 1 and 3 To Be Published
8HLA	Heteromeric ring comprised of peroxiredoxin from Thermococcus kodakaraensis (TkPrx) F42C/C46S/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F42C) and TkPrx C46S/F76C/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F76C) (Naph@(MIX|3:3)) 分子名称: 1-naphthalen-2-ylethanone, Peroxiredoxin 著者 Himiyama, T, Hamaguchi, T, Yonekura, K, Nakamura, T. 登録日 2022-11-29 公開日 2023-03-22 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (2.81 Å) 主引用文献 Unnaturally Distorted Hexagonal Protein Ring Alternatingly Reorganized from Two Distinct Chemically Modified Proteins. Bioconjug.Chem., 2023
8YPW	CDK2 and small molecular inhibitor L14 分子名称: Cyclin-dependent kinase 2, methyl 3-[4-[3-[[3-[(1-ethylsulfonylpiperidin-4-yl)carbamoyl]-1~{H}-pyrazol-4-yl]carbamoyl]-2,4-bis(fluoranyl)phenyl]piperidin-1-yl]-3-oxidanylidene-propanoate 著者 Ge, S. 登録日 2024-03-18 公開日 2025-09-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of CDK2 and L14 at 1.8 Angstorms resolution To Be Published

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