4X4L
Structure of human ALDH1A1 with inhibitor CM037
Summary for 4X4L
| Entry DOI | 10.2210/pdb4x4l/pdb |
| Related | 4WP7 |
| Descriptor | Retinal dehydrogenase 1, YTTERBIUM (III) ION, ethyl ({4-oxo-3-[3-(pyrrolidin-1-yl)propyl]-3,4-dihydro[1]benzothieno[3,2-d]pyrimidin-2-yl}sulfanyl)acetate, ... (7 entities in total) |
| Functional Keywords | oxidoreductase enzyme inhibitor, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 56505.48 |
| Authors | Morgan, C.A.,Hurley, T.D. (deposition date: 2014-12-03, release date: 2015-02-11, Last modification date: 2024-02-28) |
| Primary citation | Morgan, C.A.,Hurley, T.D. Characterization of Two Distinct Structural Classes of Selective Aldehyde Dehydrogenase 1A1 Inhibitors. J.Med.Chem., 58:1964-1975, 2015 Cited by PubMed: 25634381DOI: 10.1021/jm501900s PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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