8SWU
Structure of Clostridium perfringens PNP bound to transition state analog IMMUCILLIN H and sulfate
Summary for 8SWU
| Entry DOI | 10.2210/pdb8swu/pdb |
| Descriptor | Purine nucleoside phosphorylase, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | pentosyltransferase, purine nucleoside phosphorylase, transferase |
| Biological source | Clostridium perfringens ATCC 13124 |
| Total number of polymer chains | 3 |
| Total formula weight | 90493.72 |
| Authors | Fedorov, E.,Ghosh, A. (deposition date: 2023-05-19, release date: 2023-10-18, Last modification date: 2023-11-22) |
| Primary citation | Minnow, Y.V.T.,Schramm, V.L.,Almo, S.C.,Ghosh, A. Phosphate Binding in PNP Alters Transition-State Analogue Affinity and Subunit Cooperativity. Biochemistry, 62:3116-3125, 2023 Cited by PubMed: 37812583DOI: 10.1021/acs.biochem.3c00264 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.34 Å) |
Structure validation
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