PDB: 3066 件ウェブページステータス検索Chemie searchBIRD

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6Z2C	Engineered lipocalin C3A5 in complex with a transition state analog 分子名称: 1,7,8,9,10,10-hexachloro-4-carboxypentyl-4-aza-tricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-dione, Neutrophil gelatinase-associated lipocalin 著者 Skerra, A, Eichinger, A. 登録日 2020-05-15 公開日 2021-05-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of an engineered lipocalin that catalyzes a Diels-Alder reaction To be published
5SYE	Near-atomic resolution cryo-EM reconstruction of doubly bound Taxol- and peloruside-stabilized microtubule 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Kellogg, E.H, Nogales, E. 登録日 2016-08-10 公開日 2017-02-01 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures. J. Mol. Biol., 429, 2017
7ADO	Cryo-EM structure of human ER membrane protein complex in lipid nanodiscs 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ER membrane protein complex subunit 1, ... 著者 Braeuning, B, Prabu, J.R, Miller-Vedam, L.E, Weissman, J.S, Frost, A, Schulman, B.A. 登録日 2020-09-15 公開日 2020-12-02 最終更新日 2021-01-20 実験手法 ELECTRON MICROSCOPY (3.39 Å) 主引用文献 Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients. Elife, 9, 2020
5SYC	Near-atomic resolution cryo-EM reconstruction of peloruside-stabilized microtubule 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Kellogg, E.H, Nogales, E. 登録日 2016-08-10 公開日 2017-02-01 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures. J. Mol. Biol., 429, 2017
5TL7	Crystal structure of SARS-CoV papain-like protease in complex with C-terminal domain mouse ISG15 分子名称: Replicase polyprotein 1ab, Ubiquitin-like protein ISG15, ZINC ION 著者 Daczkowski, C.D, Dzimianski, J.V, Pegan, S.D. 登録日 2016-10-10 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species. J. Mol. Biol., 429, 2017
6OAM	Crystal Structure of ChlaDUB2 DUB domain 分子名称: Deubiquitinase and deneddylase Dub2, Ubiquitin 著者 Hausman, J.M, Das, C. 登録日 2019-03-17 公開日 2020-04-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.503 Å) 主引用文献 The Two Deubiquitinating Enzymes fromChlamydia trachomatisHave Distinct Ubiquitin Recognition Properties. Biochemistry, 59, 2020
7N9L	KirBac3.1 C71S C262S 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Inward rectifier potassium channel Kirbac3.1, POTASSIUM ION, ... 著者 Gulbis, J.M, Black, K.A. 登録日 2021-06-18 公開日 2021-12-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Ion currents through Kir potassium channels are gated by anionic lipids. Nat Commun, 13, 2022
7N9K	KirBac3.1 L124M mutant 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Inward rectifier potassium channel Kirbac3.1, N-OCTANE, ... 著者 Black, T.A, Gulbis, J.M. 登録日 2021-06-18 公開日 2021-12-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Ion currents through Kir potassium channels are gated by anionic lipids. Nat Commun, 13, 2022
7AHR	Enzyme of biosynthetic pathway 分子名称: 3-[(1-Carboxyvinyl)oxy]benzoic acid, Chorismate dehydratase, GLYCEROL 著者 Archna, A, Breithaupt, C, Stubbs, M.T. 登録日 2020-09-25 公開日 2021-10-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Mechanism of chorismate dehydratase MqnA, the first enzyme of the futalosine pathway, proceeds via substrate-assisted catalysis J.Biol.Chem., 2022
7OCF	Active state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLOTHIAZIDE, GLUTAMIC ACID, ... 著者 Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H. 登録日 2021-04-26 公開日 2021-06-09 最終更新日 2021-06-30 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Gating and modulation of a hetero-octameric AMPA glutamate receptor. Nature, 594, 2021
7BT2	Crystal structure of the SERCA2a in the E2.ATP state 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Kabashima, Y, Ogawa, H, Nakajima, R, Toyoshima, C. 登録日 2020-03-31 公開日 2020-07-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.00002861 Å) 主引用文献 What ATP binding does to the Ca2+pump and how nonproductive phosphoryl transfer is prevented in the absence of Ca2. Proc.Natl.Acad.Sci.USA, 117, 2020
7OJE	Crystal structure of the covalent complex between Tribolium castaneum deubiquitinase ZUP and Ubiquitin-PA 分子名称: 1,2-ETHANEDIOL, CITRIC ACID, Lys-63-specific deubiquitinase ZUFSP, ... 著者 Pichlo, C, Hermanns, T, Hofmann, K, Baumann, U. 登録日 2021-05-14 公開日 2022-02-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family. Nat Commun, 13, 2022
7B9C	Structure of a minimal SF3B core in complex with spliceostatin A (form I) 分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ... 著者 Cretu, C, Pena, V. 登録日 2020-12-14 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021
7P18	Crystal structure of 3-ketosteroid delta1-dehydrogenase from Sterolibacterium denitrificans in complex with 1,4-androstadiene-3,17-dione 分子名称: 3-oxosteroid 1-dehydrogenase, ANDROSTA-1,4-DIENE-3,17-DIONE, DI(HYDROXYETHYL)ETHER, ... 著者 Wojcik, P, Mrugala, B, Kurpiewska, K, Szaleniec, M. 登録日 2021-07-01 公開日 2021-07-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structure, Mutagenesis, and QM:MM Modeling of 3-Ketosteroid Delta 1 -Dehydrogenase from Sterolibacterium denitrificans ─The Role of a New Putative Membrane-Associated Domain and Proton-Relay System in Catalysis. Biochemistry, 62, 2023
7ONB	Structure of the U2 5' module of the A3'-SSA complex 分子名称: MINX, PHD finger-like domain-containing protein 5A, RNU2, ... 著者 Cretu, C, Pena, V. 登録日 2021-05-25 公開日 2021-08-04 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021
7OO6	Mechanosensitive channel MscS solubilized with DDM in closed conformation with added lipid 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, DODECYL-BETA-D-MALTOSIDE, Mechanosensitive channel of small conductance (MscS) 著者 Rasmussen, T, Flegler, V.J, Boettcher, B. 登録日 2021-05-26 公開日 2021-09-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Mechanosensitive channel gating by delipidation. Proc.Natl.Acad.Sci.USA, 118, 2021
6PTS	NMR data-driven model of KRas-GMPPNP:RBD-CRD complex tethered to a nanodisc (state A) 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... 著者 Fang, Z, Lee, K, Gasmi-Seabrook, G, Ikura, M, Marshall, C.B. 登録日 2019-07-16 公開日 2020-05-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane. Proc.Natl.Acad.Sci.USA, 117, 2020
6PTW	NMR data-driven model of KRas-GMPPNP:RBD-CRD complex tethered to a nanodisc (state B) 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... 著者 Fang, Z, Lee, K, Gasmi-Seabrook, G, Ikura, M, Marshall, C.B. 登録日 2019-07-16 公開日 2020-05-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane. Proc.Natl.Acad.Sci.USA, 117, 2020
7AN5	Enzyme of biosynthetic pathway 分子名称: 3-[(1-Carboxyvinyl)oxy]benzoic acid, Chorismate dehydratase 著者 Archna, A, Breithaupt, C, Stubbs, M.T. 登録日 2020-10-11 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Mechanism of chorismate dehydratase MqnA, the first enzyme of the futalosine pathway, proceeds via substrate-assisted catalysis J.Biol.Chem., 2022
7AN7	Enzyme of biosynthetic pathway 分子名称: 3-[(1-Carboxyvinyl)oxy]benzoic acid, Chorismate dehydratase, GLYCEROL 著者 Archna, A, Breithaupt, C, Stubbs, M.T. 登録日 2020-10-11 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Mechanism of chorismate dehydratase MqnA, the first enzyme of the futalosine pathway, proceeds via substrate-assisted catalysis J.Biol.Chem., 2022
7AN8	Enzyme of biosynthetic pathway 分子名称: 3-[(1-Carboxyvinyl)oxy]benzoic acid, Chorismate dehydratase, GLYCEROL 著者 Archna, A, Breithaupt, C, Stubbs, M.T. 登録日 2020-10-11 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Mechanism of chorismate dehydratase MqnA, the first enzyme of the futalosine pathway, proceeds via substrate-assisted catalysis J.Biol.Chem., 2022
7AN9	Enzyme of biosynthetic pathway 分子名称: 3-[(1-Carboxyvinyl)oxy]benzoic acid, Chorismate dehydratase 著者 Archna, A, Breithaupt, C, Stubbs, M.T. 登録日 2020-10-11 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Mechanism of the chorismate dehydratase MqnA, first enzyme of the futalosine pathway Chemrxiv, 2022
6PW5	Cryo-EM Structure of Thermo-Sensitive TRP Channel TRP1 from the Alga Chlamydomonas reinhardtii in Nanodiscs 分子名称: (2S)-3-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, TRP-like ion channel, ... 著者 McGoldrick, L.L, Singh, A.K, Sobolevsky, A.I. 登録日 2019-07-22 公開日 2019-09-25 最終更新日 2019-12-04 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structure of the thermo-sensitive TRP channel TRP1 from the alga Chlamydomonas reinhardtii. Nat Commun, 10, 2019
6PW4	Cryo-EM Structure of Thermo-Sensitive TRP Channel TRP1 from the Alga Chlamydomonas reinhardtii in Detergent 分子名称: (2S)-3-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... 著者 McGoldrick, L.L, Singh, A.K, Sobolevsky, A.I. 登録日 2019-07-22 公開日 2019-09-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.53 Å) 主引用文献 Structure of the thermo-sensitive TRP channel TRP1 from the alga Chlamydomonas reinhardtii. Nat Commun, 10, 2019
6QLH	Crystal structure of UbiX in complex with reduced FMN and isopentyl monophosphate 分子名称: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, Flavin prenyltransferase UbiX, Isopentenyl phosphate, ... 著者 Marshall, S.A, Leys, D. 登録日 2019-02-01 公開日 2019-06-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 The UbiX flavin prenyltransferase reaction mechanism resembles class I terpene cyclase chemistry. Nat Commun, 10, 2019

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