6PTW
NMR data-driven model of KRas-GMPPNP:RBD-CRD complex tethered to a nanodisc (state B)
Summary for 6PTW
| Entry DOI | 10.2210/pdb6ptw/pdb |
| NMR Information | BMRB: 30640 |
| Descriptor | Apolipoprotein A-I, GTPase KRas, RAF proto-oncogene serine/threonine-protein kinase, ... (8 entities in total) |
| Functional Keywords | protein-protein-bilayer complex, small gtpase, ras-raf-nanodisc complex, signaling protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 146205.05 |
| Authors | Fang, Z.,Lee, K.,Gasmi-Seabrook, G.,Ikura, M.,Marshall, C.B. (deposition date: 2019-07-16, release date: 2020-05-13, Last modification date: 2023-06-14) |
| Primary citation | Fang, Z.,Lee, K.Y.,Huo, K.G.,Gasmi-Seabrook, G.,Zheng, L.,Moghal, N.,Tsao, M.S.,Ikura, M.,Marshall, C.B. Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane. Proc.Natl.Acad.Sci.USA, 117:12101-12108, 2020 Cited by PubMed: 32414921DOI: 10.1073/pnas.1914076117 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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