7ADO

Cryo-EM structure of human ER membrane protein complex in lipid nanodiscs

Summary for 7ADO

• Entry DOI: 10.2210/pdb7ado/pdb
• EMDB information: 11732
• Descriptor: ER membrane protein complex subunit 1, Unassigned helix, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• Functional Keywords: er membrane protein, emc, membrane protein biogenesis, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 308543.84

Authors

Braeuning, B.,Prabu, J.R.,Miller-Vedam, L.E.,Weissman, J.S.,Frost, A.,Schulman, B.A. (deposition date: 2020-09-15, release date: 2020-12-02, Last modification date: 2021-01-20)

• Primary citation: Miller-Vedam, L.E.,Brauning, B.,Popova, K.D.,Schirle Oakdale, N.T.,Bonnar, J.L.,Prabu, J.R.,Boydston, E.A.,Sevillano, N.,Shurtleff, M.J.,Stroud, R.M.,Craik, C.S.,Schulman, B.A.,Frost, A.,Weissman, J.S.; Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.; Elife, 9:-, 2020; PubMed: 33236988; DOI: 10.7554/eLife.62611

Experimental method

ELECTRON MICROSCOPY (3.39 Å)