7PDT
 
 | | Crystal structure of a mutated form of RXRalpha ligand binding domain in complex with BMS649 and a coactivator fragment | | 分子名称: | 4-[2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-[1,3]DIOXOLAN-2-YL]-BENZOIC ACID, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha | | 著者 | le Maire, A, Bourguet, W, Guee, L. | | 登録日 | 2021-08-07 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Design and in vitro characterization of RXR variants as tools to investigate the biological role of endogenous rexinoids.
J.Mol.Endocrinol., 69, 2022
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6V89
 | | Human CtBP1 (28-375) in complex with AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, C-terminal-binding protein 1, CALCIUM ION, ... | | 著者 | Royer, W.E. | | 登録日 | 2019-12-10 | | 公開日 | 2021-02-03 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP).
J.Biol.Chem., 296, 2021
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3LM9
 | | Crystal structure of fructokinase with ADP and Fructose bound in the active site | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, ZINC ION, ... | | 著者 | Nocek, B, Stein, A, Cuff, M, Volkart, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-01-29 | | 公開日 | 2010-03-09 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structural studies of ROK fructokinase YdhR from Bacillus subtilis: insights into substrate binding and fructose specificity.
J.Mol.Biol., 406, 2011
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7QAA
 | | Crystal structure of RARalpha/RXRalpha ligand binding domain heterodimer in complex with BMS614 and oleic acid | | 分子名称: | 4-[(4,4-DIMETHYL-1,2,3,4-TETRAHYDRO-[1,2']BINAPTHALENYL-7-CARBONYL)-AMINO]-BENZOIC ACID, Isoform Alpha-1-deltaBC of Retinoic acid receptor alpha, OLEIC ACID, ... | | 著者 | le Maire, A, Vivat, V, Guee, L, Blanc, P, Malosse, C, Chamot-Rooke, J, Germain, P, Bourguet, w. | | 登録日 | 2021-11-16 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Design and in vitro characterization of RXR variants as tools to investigate the biological role of endogenous rexinoids.
J.Mol.Endocrinol., 69, 2022
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3VVZ
 | | Crystal Strucuture of The Rhodamine 6G-Bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | 分子名称: | Putative regulatory protein, RHODAMINE 6G, SULFATE ION | | 著者 | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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3VVX
 | | Crystal Strucuture of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | 分子名称: | Putative regulatory protein, SULFATE ION | | 著者 | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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3VVY
 | | Crystal Strucuture of The Ethidium-Bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | 分子名称: | ETHIDIUM, Putative regulatory protein | | 著者 | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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3VW1
 | | Crystal Strucuture of the Crystal Violet-Bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | 分子名称: | CHLORIDE ION, CRYSTAL VIOLET, Putative regulatory protein, ... | | 著者 | Sakurai, K, Yamasaki, S, Nakashima, R, Nikaido, E, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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3VW0
 | | Crystal Structure of The Dequalinum-bound Form of RamR (Transcriptional Regulator of TetR Family) From Salmonella Typhimurium | | 分子名称: | DEQUALINIUM, Putative regulatory protein, SULFATE ION | | 著者 | Sakurai, K, Yamasaki, S, Nakashima, R, Nikaido, E, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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3VOD
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3VK0
 | | Crystal Structure of hypothetical transcription factor NHTF from Neisseria | | 分子名称: | Transcriptional regulator | | 著者 | Wang, H.-C, Ko, T.-P, Wu, M.-L, Wu, H.-J, Ku, S.-C, Wang, A.H.-J. | | 登録日 | 2011-11-01 | | 公開日 | 2012-03-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Neisseria conserved protein DMP19 is a DNA mimic protein that prevents DNA binding to a hypothetical nitrogen-response transcription factor
Nucleic Acids Res., 2012
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2KIZ
 | | Solution structure of Arkadia RING-H2 finger domain | | 分子名称: | E3 ubiquitin-protein ligase Arkadia, ZINC ION | | 著者 | Kandias, N.G, Chasapis, C.T, Bentrop, D, Episkopou, V, Spyroulias, G.A. | | 登録日 | 2009-05-13 | | 公開日 | 2010-05-19 | | 最終更新日 | 2013-03-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR-based insights into the conformational and interaction properties of Arkadia RING-H2 E3 Ub ligase.
Proteins, 80, 2012
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3VW2
 | | Crystal Strucuture of The Berberine-bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | 分子名称: | BERBERINE, Putative regulatory protein, SULFATE ION | | 著者 | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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8G1U
 | | Structure of the methylosome-Lsm10/11 complex | | 分子名称: | ADENOSINE, Methylosome protein 50, Methylosome subunit pICln, ... | | 著者 | Lin, M, Paige, A, Tong, L. | | 登録日 | 2023-02-03 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | | 主引用文献 | In vitro methylation of the U7 snRNP subunits Lsm11 and SmE by the PRMT5/MEP50/pICln methylosome.
Rna, 29, 2023
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2Z32
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6ZVH
 | | EDF1-ribosome complex | | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | 著者 | Best, K.M, Denk, T, Cheng, J, Thoms, M, Berninghausen, O, Beckmann, R. | | 登録日 | 2020-07-24 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | EDF1 coordinates cellular responses to ribosome collisions.
Elife, 9, 2020
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3VOV
 | | Crystal Structure of ROK Hexokinase from Thermus thermophilus | | 分子名称: | GLYCEROL, Glucokinase, ZINC ION | | 著者 | Nakamura, T, Kashima, Y, Mine, S, Oku, T, Uegaki, K. | | 登録日 | 2012-02-21 | | 公開日 | 2012-06-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Characterization and crystal structure of the thermophilic ROK hexokinase from Thermus thermophilus
J.Biosci.Bioeng., 2012
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8H3F
 | | Cryo-EM Structure of the KBTBD2-CRL3-CSN complex | | 分子名称: | COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... | | 著者 | Hu, Y, Mao, Q, Chen, Z, Sun, L. | | 登録日 | 2022-10-08 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (6.73 Å) | | 主引用文献 | Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
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8H3A
 | | Cryo-EM Structure of the KBTBD2-CRL3~N8(removed)-CSN complex | | 分子名称: | COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... | | 著者 | Hu, Y, Mao, Q, Chen, Z, Sun, L. | | 登録日 | 2022-10-08 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (7.51 Å) | | 主引用文献 | Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
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8H38
 | | Cryo-EM Structure of the KBTBD2-CRL3~N8-CSN(mutate) complex | | 分子名称: | COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... | | 著者 | Hu, Y, Mao, Q, Chen, Z, Sun, L. | | 登録日 | 2022-10-08 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.25 Å) | | 主引用文献 | Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
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1BIX
 | | THE CRYSTAL STRUCTURE OF THE HUMAN DNA REPAIR ENDONUCLEASE HAP1 SUGGESTS THE RECOGNITION OF EXTRA-HELICAL DEOXYRIBOSE AT DNA ABASIC SITES | | 分子名称: | AP ENDONUCLEASE 1, PLATINUM (II) ION, SAMARIUM (III) ION | | 著者 | Gorman, M.A, Morera, S, Rothwell, D.G, De La Fortelle, E, Mol, C.D, Tainer, J.A, Hickson, I.D, Freemont, P.S. | | 登録日 | 1998-06-19 | | 公開日 | 1999-06-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites.
EMBO J., 16, 1997
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1OHJ
 | | HUMAN DIHYDROFOLATE REDUCTASE, MONOCLINIC (P21) CRYSTAL FORM | | 分子名称: | DIHYDROFOLATE REDUCTASE, N-(4-CARBOXY-4-{4-[(2,4-DIAMINO-PTERIDIN-6-YLMETHYL)-AMINO]-BENZOYLAMINO}-BUTYL)-PHTHALAMIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W. | | 登録日 | 1997-09-17 | | 公開日 | 1998-04-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Comparison of two independent crystal structures of human dihydrofolate reductase ternary complexes reduced with nicotinamide adenine dinucleotide phosphate and the very tight-binding inhibitor PT523.
Biochemistry, 36, 1997
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1OHK
 | | HUMAN DIHYDROFOLATE REDUCTASE, ORTHORHOMBIC (P21 21 21) CRYSTAL FORM | | 分子名称: | DIHYDROFOLATE REDUCTASE, N-(4-CARBOXY-4-{4-[(2,4-DIAMINO-PTERIDIN-6-YLMETHYL)-AMINO]-BENZOYLAMINO}-BUTYL)-PHTHALAMIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W. | | 登録日 | 1997-09-17 | | 公開日 | 1998-05-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Comparison of two independent crystal structures of human dihydrofolate reductase ternary complexes reduced with nicotinamide adenine dinucleotide phosphate and the very tight-binding inhibitor PT523.
Biochemistry, 36, 1997
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4IEM
 | | Human apurinic/apyrimidinic endonuclease (APE1) with product DNA and Mg2+ | | 分子名称: | DNA (5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*C)-3'), DNA (5'-D(P*(3DR)P*GP*AP*TP*CP*G)-3'), ... | | 著者 | Tsutakawa, S.E, Mol, C.D, Arvai, A.S, Tainer, J.A. | | 登録日 | 2012-12-13 | | 公開日 | 2013-01-23 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3936 Å) | | 主引用文献 | Conserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair Enzymes.
J.Biol.Chem., 288, 2013
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1MU4
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