8G1U

Structure of the methylosome-Lsm10/11 complex

Summary for 8G1U

Entry DOI	10.2210/pdb8g1u/pdb
EMDB information	29677
Descriptor	Protein arginine N-methyltransferase 5, Methylosome protein 50, Methylosome subunit pICln, ... (5 entities in total)
Functional Keywords	methylation, gene regulation, transferase
Biological source	Homo sapiens (human) More
Total number of polymer chains	16
Total formula weight	701611.60
Authors	Lin, M.,Paige, A.,Tong, L. (deposition date: 2023-02-03, release date: 2023-08-23, Last modification date: 2023-10-25)
Primary citation	Yang, X.C.,Desotell, A.,Lin, M.H.,Paige, A.S.,Malinowska, A.,Sun, Y.,Aik, W.S.,Dadlez, M.,Tong, L.,Dominski, Z. In vitro methylation of the U7 snRNP subunits Lsm11 and SmE by the PRMT5/MEP50/pICln methylosome. Rna, 29:1673-1690, 2023 Cited by PubMed: 37562960 DOI: 10.1261/rna.079709.123 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.83 Å)

Structure validation