8G1U
Structure of the methylosome-Lsm10/11 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (A, E, I, M) | Protein arginine N-methyltransferase 5 | polymer | 637 | 72766.7 | 4 | UniProt (O14744) Pfam (PF17285) Pfam (PF05185) Pfam (PF17286) | Homo sapiens (human) | 72 kDa ICln-binding protein,Histone-arginine N-methyltransferase PRMT5,Jak-binding protein 1,Shk1 kinase-binding protein 1 homolog,SKB1Hs |
| 2 | B, E, H, K (B, F, J, N) | Methylosome protein 50 | polymer | 342 | 36757.2 | 4 | UniProt (Q9BQA1) Pfam (PF00400) | Homo sapiens (human) | MEP-50,Androgen receptor cofactor p44,WD repeat-containing protein 77,p44/Mep50 |
| 3 | C, F, I, L (C, G, K, O) | Methylosome subunit pICln | polymer | 236 | 26039.0 | 4 | UniProt (Q61189) Pfam (PF03517) | Mus musculus (house mouse) | Chloride channel,nucleotide sensitive 1A,Chloride conductance regulatory protein ICln,I(Cln),Chloride ion current inducer protein,ClCI |
| 4 | M, N, O, P (D, H, L, P) | U7 snRNA-associated Sm-like protein LSm11 | polymer | 360 | 39572.8 | 4 | UniProt (P83369) | Homo sapiens (human) | |
| 5 | Q, R, S, T (A, E, I, M) | ADENOSINE | non-polymer | 267.2 | 4 | Chemie (ADN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 700542.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1069.0 | |
| All* | Total formula weight | 701611.6 |
