9EWQ
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4ZLA
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6Y8Z
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![BU of 6y8z by Molmil](/molmil-images/mine/6y8z) | Structure of Baltic Herring (Clupea Harengus) Phosphoglucomutase 5 (PGM5) | 分子名称: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | 著者 | Gustafsson, R, Eckhard, U, Selmer, M. | 登録日 | 2020-03-06 | 公開日 | 2020-12-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure and Characterization of Phosphoglucomutase 5 from Atlantic and Baltic Herring-An Inactive Enzyme with Intact Substrate Binding. Biomolecules, 10, 2020
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6YG1
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![BU of 6yg1 by Molmil](/molmil-images/mine/6yg1) | Crystal structure of MKK7 (MAP2K7) in an active state, allosterically triggered by the N-terminal helix | 分子名称: | 1,2-ETHANEDIOL, Dual specificity mitogen-activated protein kinase kinase 7, SODIUM ION | 著者 | Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC), Scottish Structural Proteomics Facility (SSPF) | 登録日 | 2020-03-27 | 公開日 | 2020-08-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Catalytic Domain Plasticity of MKK7 Reveals Structural Mechanisms of Allosteric Activation and Diverse Targeting Opportunities. Cell Chem Biol, 27, 2020
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6HJA
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![BU of 6hja by Molmil](/molmil-images/mine/6hja) | Xray structure of GLIC in complex with glutarate | 分子名称: | CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECANE, ... | 著者 | Fourati, Z, Delarue, M. | 登録日 | 2018-09-03 | 公開日 | 2019-09-18 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel. Acta Crystallogr D Struct Biol, 76, 2020
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4KWF
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![BU of 4kwf by Molmil](/molmil-images/mine/4kwf) | Crystal Structure Analysis of ALDH2+ALDiB33 | 分子名称: | 1,2-ETHANEDIOL, 1-benzyl-1H-indole-2,3-dione, Aldehyde dehydrogenase, ... | 著者 | Hurley, T.D, Kimble-Hill, A.C. | 登録日 | 2013-05-24 | 公開日 | 2014-04-09 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Development of selective inhibitors for aldehyde dehydrogenases based on substituted indole-2,3-diones. J.Med.Chem., 57, 2014
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4ZZC
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![BU of 4zzc by Molmil](/molmil-images/mine/4zzc) | The GLIC pentameric Ligand-Gated Ion Channel open form complexed to xenon | 分子名称: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | 著者 | Sauguet, L, Fourati, Z, Prange, T, Delarue, M, Colloc'h, N. | 登録日 | 2015-05-22 | 公開日 | 2016-03-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural Basis for Xenon Inhibition in a Cationic Pentameric Ligand-Gated Ion Channel. Plos One, 11, 2016
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5A1A
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![BU of 5a1a by Molmil](/molmil-images/mine/5a1a) | 2.2 A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor | 分子名称: | 2-phenylethyl 1-thio-beta-D-galactopyranoside, BETA-GALACTOSIDASE, MAGNESIUM ION, ... | 著者 | Bartesaghi, A, Merk, A, Banerjee, S, Matthies, D, Wu, X, Milne, J, Subramaniam, S. | 登録日 | 2015-04-29 | 公開日 | 2015-05-06 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | 2.2 A Resolution Cryo-Em Structure of Beta-Galactosidase in Complex with a Cell-Permeant Inhibitor Science, 348, 2015
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5UQA
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8WA5
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4KWG
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![BU of 4kwg by Molmil](/molmil-images/mine/4kwg) | Crystal Structure Analysis of ALDH2+ALDiB13 | 分子名称: | 1,2-ETHANEDIOL, 7-bromo-5-methyl-1H-indole-2,3-dione, Aldehyde dehydrogenase, ... | 著者 | Hurley, T.D, Kimble-Hill, A.C. | 登録日 | 2013-05-24 | 公開日 | 2014-04-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Development of selective inhibitors for aldehyde dehydrogenases based on substituted indole-2,3-diones. J.Med.Chem., 57, 2014
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4ZZB
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![BU of 4zzb by Molmil](/molmil-images/mine/4zzb) | The GLIC pentameric Ligand-Gated Ion Channel Locally-closed form complexed to xenon | 分子名称: | ACETATE ION, CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Sauguet, L, Fourati, Z, Prange, T, Delarue, M, Colloc'h, N. | 登録日 | 2015-05-22 | 公開日 | 2016-03-02 | 最終更新日 | 2018-11-21 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural Basis for Xenon Inhibition in a Cationic Pentameric Ligand-Gated Ion Channel. Plos One, 11, 2016
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4FEB
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![BU of 4feb by Molmil](/molmil-images/mine/4feb) | Crystal Structure of Htt36Q3H-EX1-X1-C2(Beta) | 分子名称: | Maltose-binding periplasmic protein,Huntingtin, SODIUM ION, ZINC ION | 著者 | Kim, M. | 登録日 | 2012-05-29 | 公開日 | 2013-03-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Beta conformation of polyglutamine track revealed by a crystal structure of Huntingtin N-terminal region with insertion of three histidine residues. Prion, 7, 2013
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6RLO
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![BU of 6rlo by Molmil](/molmil-images/mine/6rlo) | Crystal structure of AT1412dm Fab fragment in complex with CD9 large extracellular loop | 分子名称: | AT1412dm Fab Fragment (Heavy Chain), AT1412dm Fab Fragment (Light Chain), CD9 antigen, ... | 著者 | Neviani, V, Pearce, N.M, Pos, W, Schotte, R, Spits, H, Gros, P. | 登録日 | 2019-05-02 | 公開日 | 2021-05-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis of a homo-dimerization site in tetraspanin CD9 targeted by a melanoma patient-derived antibody To Be Published
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4D1I
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![BU of 4d1i by Molmil](/molmil-images/mine/4d1i) | The structure of the GH35 beta-galactosidase Bgl35A from Cellvibrio japonicus | 分子名称: | ACETATE ION, BETA-GALACTOSIDASE, PUTATIVE, ... | 著者 | Larsbrink, J, Thompson, A.J, Lundqvist, M, Gardner, J.G, Davies, G.J, Brumer, H. | 登録日 | 2014-05-02 | 公開日 | 2014-05-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A Complex Gene Locus Enables Xyloglucan Utilization in the Model Saprophyte Cellvibrio Japonicus. Mol.Microbiol., 94, 2014
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5B06
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![BU of 5b06 by Molmil](/molmil-images/mine/5b06) | Lysozyme (denatured by NaOD and refolded) | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... | 著者 | Kita, A, Morimoto, Y. | 登録日 | 2015-10-28 | 公開日 | 2016-01-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | An Effective Deuterium Exchange Method for Neutron Crystal Structure Analysis with Unfolding-Refolding Processes Mol Biotechnol., 58, 2016
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3N25
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![BU of 3n25 by Molmil](/molmil-images/mine/3n25) | The structure of muscle pyruvate kinase in complex with proline, pyruvate, and Mn2+ | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Fenton, A.W, Johnson, T.A, Holyoak, T. | 登録日 | 2010-05-17 | 公開日 | 2010-07-28 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | The pyruvate kinase model system, a cautionary tale for the use of osmolyte perturbations to support conformational equilibria in allostery. Protein Sci., 19, 2010
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4GEZ
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![BU of 4gez by Molmil](/molmil-images/mine/4gez) | Structure of a neuraminidase-like protein from A/bat/Guatemala/164/2009 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Yang, H, Carney, P.J, Donis, R.O, Stevens, J. | 登録日 | 2012-08-02 | 公開日 | 2012-09-26 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of two subtype N10 neuraminidase-like proteins from bat influenza A viruses reveal a diverged putative active site. Proc.Natl.Acad.Sci.USA, 109, 2012
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5C4W
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![BU of 5c4w by Molmil](/molmil-images/mine/5c4w) | Crystal structure of coxsackievirus A16 | 分子名称: | CHLORIDE ION, POTASSIUM ION, SODIUM ION, ... | 著者 | Ren, J, Wang, X, Zhu, L, Hu, Z, Gao, Q, Yang, P, Li, X, Wang, J, Shen, X, Fry, E.E, Rao, Z, Stuart, D.I. | 登録日 | 2015-06-18 | 公開日 | 2015-08-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity. J.Virol., 89, 2015
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6FMQ
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![BU of 6fmq by Molmil](/molmil-images/mine/6fmq) | Keap1 - peptide complex | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ACY-SC1-GLU-THR-GLY-GLU-LEU, ... | 著者 | Talapatra, S.K, Kozielski, F, Wells, G, Georgakopoulos, N.D. | 登録日 | 2018-02-02 | 公開日 | 2018-08-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Modified Peptide Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction Incorporating Unnatural Amino Acids. Chembiochem, 19, 2018
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5Y7D
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![BU of 5y7d by Molmil](/molmil-images/mine/5y7d) | Crystal structure of human Endothelial-overexpressed LPS associated factor 1 | 分子名称: | CHLORIDE ION, GLYCEROL, Protein CXorf40A, ... | 著者 | Park, S.H, Kim, M.J, Park, J.S, Kim, H.J, Han, B.W. | 登録日 | 2017-08-17 | 公開日 | 2018-08-22 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Crystal Structure of Human EOLA1 Implies Its Possibility of RNA Binding. Molecules, 24, 2019
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6MR7
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![BU of 6mr7 by Molmil](/molmil-images/mine/6mr7) | DNA polymerase beta substrate complex with templating adenine and incoming Fapy-dGTP analog | 分子名称: | 1,2-ETHANEDIOL, 1-[2-amino-5-(formylamino)-6-oxo-1,6-dihydropyrimidin-4-yl]-2,5-anhydro-1,3-dideoxy-6-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-ribo-hexitol, CALCIUM ION, ... | 著者 | Freudenthal, B.D, Smith, M.R, Wilson, S.H, Beard, W.A. | 登録日 | 2018-10-11 | 公開日 | 2019-01-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.144 Å) | 主引用文献 | A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition. Nucleic Acids Res., 47, 2019
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6N1C
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6MYK
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![BU of 6myk by Molmil](/molmil-images/mine/6myk) | Pleurotus ostreatus OstreolysinA mutant E69A with Bis-Tris | 分子名称: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Ostreolysin A6, ... | 著者 | Tomchick, D.R, Radhakrishnan, A, Endapally, S. | 登録日 | 2018-11-01 | 公開日 | 2019-02-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Molecular Discrimination between Two Conformations of Sphingomyelin in Plasma Membranes. Cell, 176, 2019
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5P9R
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![BU of 5p9r by Molmil](/molmil-images/mine/5p9r) | |