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4L9S
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Crystal Structure of H-Ras G12C, GDP-bound
分子名称: CALCIUM ION, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-06-18
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.606 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4LA0
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BU of 4la0 by Molmil
X-ray study of human serum albumin complexed with bicalutamide
分子名称: R-BICALUTAMIDE, SERUM ALBUMIN
著者Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C.
登録日2013-06-18
公開日2013-07-24
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural studies of several clinically important oncology drugs in complex with human serum albumin.
Biochim.Biophys.Acta, 1830, 2013
4LAY
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BU of 4lay by Molmil
Crystal Structure Analysis of FKBP52, Complex with I63
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP4, {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid
著者Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F.
登録日2013-06-20
公開日2013-08-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge.
J.Mol.Biol., 425, 2013
4LB4
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BU of 4lb4 by Molmil
Crystal structure of human AR complexed with NADP+ and {2-[(4-bromo-2,3,5,6-tetrafluorobenzyl)carbamoyl]-5-chlorophenoxy}acetic acid
分子名称: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {2-[(4-bromo-2,3,5,6-tetrafluorobenzyl)carbamoyl]-5-chlorophenoxy}acetic acid
著者Cousido-Siah, A, Mitschler, A, Ruiz, F.X, Fanfrlik, J, Kolar, M, Hobza, P, Podjarny, A.
登録日2013-06-20
公開日2014-04-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (0.8 Å)
主引用文献Modulation of aldose reductase inhibition by halogen bond tuning.
Acs Chem.Biol., 8, 2013
4LBG
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BU of 4lbg by Molmil
Crystal structure of probable sugar kinase protein from Rhizobium Etli CFN 42 complexed with adenosine
分子名称: ADENOSINE, DIMETHYL SULFOXIDE, POTASSIUM ION, ...
著者Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2013-06-20
公開日2013-07-03
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of probable sugar kinase protein from Rhizobium Etli CFN 42 complexed with adenosine
To be Published
4LCK
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BU of 4lck by Molmil
Co-crystal structure of a T-box riboswitch stem I domain in complex with its cognate tRNA
分子名称: MAGNESIUM ION, Ribosomal protein YbxF, STRONTIUM ION, ...
著者Zhang, J, Ferre-D'Amare, A.R.
登録日2013-06-21
公開日2013-07-31
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Co-crystal structure of a T-box riboswitch stem I domain in complex with its cognate tRNA.
Nature, 500, 2013
4LAK
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BU of 4lak by Molmil
Crystal structure of Cordyceps militaris IDCase D323N mutant in apo form
分子名称: Uracil-5-carboxylate decarboxylase, ZINC ION
著者Xu, S, Li, W, Zhu, J, Wang, R, Li, Z, Xu, G.L, Ding, J.
登録日2013-06-20
公開日2013-10-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4LDJ
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BU of 4ldj by Molmil
Crystal Structure of a GDP-bound G12C Oncogenic Mutant of Human GTPase KRas
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Hunter, J.C, Gurbani, D, Chen, Z, Westover, K.D.
登録日2013-06-24
公開日2014-06-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C.
Proc.Natl.Acad.Sci.USA, 111, 2014
4LE9
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BU of 4le9 by Molmil
Crystal structure of a chimeric c-Src-SH3 domain
分子名称: Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
著者Camara-Artigas, A, Martinez-Rodriguez, S, Ortiz-Salmeron, E, Martin-Garcia, J.M.
登録日2013-06-25
公開日2014-05-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.344 Å)
主引用文献3D domain swapping in a chimeric c-Src SH3 domain takes place through two hinge loops.
J.Struct.Biol., 186, 2014
4LAV
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BU of 4lav by Molmil
Crystal Structure Analysis of FKBP52, Crystal Form II
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP4, SULFATE ION
著者Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F.
登録日2013-06-20
公開日2013-08-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge.
J.Mol.Biol., 425, 2013
4LBY
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BU of 4lby by Molmil
Identifying ligand binding hot spots in proteins using brominated fragments
分子名称: AMMONIUM ION, Elongation factor Tu-A, MAGNESIUM ION, ...
著者Groftehauge, M.K, Therkelsen, M, Taaning, R, Skrydstrup, T, Morth, J.P, Nissen, P.
登録日2013-06-21
公開日2013-09-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.692 Å)
主引用文献Identifying ligand-binding hot spots in proteins using brominated fragments.
Acta Crystallogr.,Sect.F, 69, 2013
4LCA
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BU of 4lca by Molmil
Crystal structure of probable sugar kinase protein from Rhizobium Etli CFN 42 complexed with thymidine
分子名称: ADENOSINE, DIMETHYL SULFOXIDE, POTASSIUM ION, ...
著者Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2013-06-21
公開日2013-07-03
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of probable sugar kinase protein from Rhizobium Etli CFN 42 complexed with thymidine
To be Published
4LFB
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BU of 4lfb by Molmil
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
分子名称: 16S rRNA, MAGNESIUM ION, NEOMYCIN, ...
著者Demirci, H, Belardinelli, R, Carr, J, Murphy IV, F, Jogl, G, Dahlberg, A.E, Gregory, S.T.
登録日2013-06-26
公開日2014-07-02
最終更新日2025-02-19
実験手法X-RAY DIFFRACTION (3.009 Å)
主引用文献Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
to be published, 2013
4LEC
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BU of 4lec by Molmil
Human Methyltransferase-Like Protein 21A
分子名称: Protein-lysine methyltransferase METTL21A, S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN ATOM OR ION
著者Dong, A, Zeng, H, Fenner, M, Wernimont, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC)
登録日2013-06-25
公開日2013-07-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献The Crystal Structure of Human Methyltransferase-Like Protein 21A in Complex with SAH
To be Published
4LII
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BU of 4lii by Molmil
Crystal structure of an apoptosis-inducing factor, mitochondrion-associated, 1 (AIFM1) from Homo sapiens at 1.88 A resolution
分子名称: 1,2-ETHANEDIOL, Apoptosis-inducing factor 1, mitochondrial, ...
著者Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
登録日2013-07-02
公開日2013-09-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Crystal structure of an apoptosis-inducing factor, mitochondrion-associated, 1 (AIFM1) from Homo sapiens at 1.88 A resolution
To be published
4LIW
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BU of 4liw by Molmil
CcmK1 Carboxysome Shell Protein from Synechocystis PCC6803, L11K Point Mutant
分子名称: Carbon dioxide-concentrating mechanism protein CcmK homolog 1, SULFATE ION
著者Thompson, M.C, Yeates, T.O.
登録日2013-07-03
公開日2014-01-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A challenging interpretation of a hexagonally layered protein structure.
Acta Crystallogr.,Sect.D, 70, 2014
4LKP
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BU of 4lkp by Molmil
Crystal Structure of Apo Human Epidermal Fatty Acid Binding Protein (FABP5)
分子名称: AMMONIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Armstrong, E.H, Ortlund, E.A.
登録日2013-07-08
公開日2014-03-26
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor beta / delta (FABP5-PPAR beta / delta ) signaling pathway.
J.Biol.Chem., 289, 2014
4LLN
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BU of 4lln by Molmil
Crystal structure of S. aureus MepR-DNA complex
分子名称: MepR, Palindromized mepR operator sequence
著者Birukou, I, Brennan, R.G.
登録日2013-07-09
公開日2014-05-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.842 Å)
主引用文献Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR.
Nucleic Acids Res., 42, 2014
4LMF
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BU of 4lmf by Molmil
C1s CUB1-EGF-CUB2
分子名称: CALCIUM ION, Complement C1s subcomponent heavy chain, SODIUM ION
著者Wallis, R, Venkatraman Girija, U, Moody, P.C.E, Marshall, J.E.
登録日2013-07-10
公開日2013-08-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.921 Å)
主引用文献Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LAD
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BU of 4lad by Molmil
Crystal Structure of the Ube2g2:RING-G2BR complex
分子名称: E3 ubiquitin-protein ligase AMFR, OXALATE ION, Ubiquitin-conjugating enzyme E2 G2, ...
著者Liang, Y.-H, Li, J, Das, R, Byrd, R.A, Ji, X.
登録日2013-06-19
公開日2013-08-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
Embo J., 32, 2013
4LAW
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BU of 4law by Molmil
Crystal Structure Analysis of FKBP52, Crystal Form III
分子名称: DIMETHYL SULFOXIDE, Peptidyl-prolyl cis-trans isomerase FKBP4
著者Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F.
登録日2013-06-20
公開日2013-08-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge.
J.Mol.Biol., 425, 2013
4LNW
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BU of 4lnw by Molmil
Crystal structure of TR-alpha bound to T3 in a second site
分子名称: 3,5,3'TRIIODOTHYRONINE, Thyroid hormone receptor alpha
著者Puhl, A.C, Aparicio, R, Polikarpov, I.
登録日2013-07-12
公開日2014-03-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Identification of a new hormone-binding site on the surface of thyroid hormone receptor.
Mol.Endocrinol., 28, 2014
4LC4
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BU of 4lc4 by Molmil
Crystal structure of probable sugar kinase protein from Rhizobium Etli CFN 42 complexed with guanosine
分子名称: ADENOSINE, DIMETHYL SULFOXIDE, GUANOSINE, ...
著者Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2013-06-21
公開日2013-07-03
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of probable sugar kinase protein from Rhizobium Etli CFN 42 complexed with guanosine
To be Published
4LCN
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Crytsal structure of NE0047 in complex with 2'-DEOXY-GUANOSINE
分子名称: 1,2-ETHANEDIOL, 2'-DEOXY-GUANOSINE, Cytidine and deoxycytidylate deaminase zinc-binding region, ...
著者Anand, R, Bitra, A, Biswas, A.
登録日2013-06-22
公開日2014-01-22
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase
Biochemistry, 52, 2013
4LD4
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Crystal structure of NE0047 in complex with cytosine
分子名称: 6-AMINOPYRIMIDIN-2(1H)-ONE, Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION
著者Bitra, A, Biswas, A, Anand, R.
登録日2013-06-24
公開日2014-01-22
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase
Biochemistry, 52, 2013

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件を2025-07-09に公開中

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