4LLN

Crystal structure of S. aureus MepR-DNA complex

Summary for 4LLN

Entry DOI	10.2210/pdb4lln/pdb
Related	4LLL
Descriptor	MepR, Palindromized mepR operator sequence (2 entities in total)
Functional Keywords	multidrug resistance, winged helix-turn-helix, transcription repression, mepr operator, transcription-dna complex, transcription/dna
Biological source	Staphylococcus aureus More
Total number of polymer chains	12
Total formula weight	141768.61
Authors	Birukou, I.,Brennan, R.G. (deposition date: 2013-07-09, release date: 2014-05-14, Last modification date: 2023-09-20)
Primary citation	Birukou, I.,Seo, S.M.,Schindler, B.D.,Kaatz, G.W.,Brennan, R.G. Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR. Nucleic Acids Res., 42:2774-2788, 2014 Cited by PubMed: 24293644 DOI: 10.1093/nar/gkt1215 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.842 Å)

Structure validation