4LNW

Crystal structure of TR-alpha bound to T3 in a second site

Summary for 4LNW

Entry DOI	10.2210/pdb4lnw/pdb
Related	3ILZ 3JZB 4LNX
Descriptor	Thyroid hormone receptor alpha, 3,5,3'TRIIODOTHYRONINE (3 entities in total)
Functional Keywords	mainly alpha orthogonal bundle, transcription factor, transcription
Biological source	Homo sapiens (human)
Cellular location	Nucleus: P10827
Total number of polymer chains	1
Total formula weight	32079.89
Authors	Puhl, A.C.,Aparicio, R.,Polikarpov, I. (deposition date: 2013-07-12, release date: 2014-03-19, Last modification date: 2023-11-15)
Primary citation	Souza, P.C.,Puhl, A.C.,Martinez, L.,Aparicio, R.,Nascimento, A.S.,Figueira, A.C.,Nguyen, P.,Webb, P.,Skaf, M.S.,Polikarpov, I. Identification of a new hormone-binding site on the surface of thyroid hormone receptor. Mol.Endocrinol., 28:534-545, 2014 Cited by PubMed: 24552590 DOI: 10.1210/me.2013-1359 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation