4LNX
Crystal structure of TR-alpha bound to T4 in a second site
Summary for 4LNX
Entry DOI | 10.2210/pdb4lnx/pdb |
Related | 3ILZ 3JZB 4LNW |
Descriptor | Thyroid hormone receptor alpha, 3,5,3',5'-TETRAIODO-L-THYRONINE, 3,5,3'TRIIODOTHYRONINE, ... (4 entities in total) |
Functional Keywords | mainly alpha orthogonal bundle, transcription factor, transcription |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P10827 |
Total number of polymer chains | 1 |
Total formula weight | 32205.79 |
Authors | Puhl, A.C.,Aparicio, R.,Polikarpov, I. (deposition date: 2013-07-12, release date: 2014-03-19, Last modification date: 2023-11-15) |
Primary citation | Souza, P.C.,Puhl, A.C.,Martinez, L.,Aparicio, R.,Nascimento, A.S.,Figueira, A.C.,Nguyen, P.,Webb, P.,Skaf, M.S.,Polikarpov, I. Identification of a new hormone-binding site on the surface of thyroid hormone receptor. Mol.Endocrinol., 28:534-545, 2014 Cited by PubMed: 24552590DOI: 10.1210/me.2013-1359 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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