4LNX
Crystal structure of TR-alpha bound to T4 in a second site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thyroid hormone receptor alpha | polymer | 267 | 30777.9 | 1 | UniProt (P10827) Pfam (PF00104) | Homo sapiens (human) | Nuclear receptor subfamily 1 group A member 1, V-erbA-related protein 7, EAR-7, c-erbA-1, c-erbA-alpha |
| 2 | B (A) | 3,5,3',5'-TETRAIODO-L-THYRONINE | non-polymer | 776.9 | 1 | Chemie (T44) | |||
| 3 | C (A) | 3,5,3'TRIIODOTHYRONINE | non-polymer | 651.0 | 1 | Chemie (T3) | |||
| 4 | D (A) | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence modifications
A: 148 - 410 (UniProt: P10827)
| PDB | External Database | Details |
|---|---|---|
| Gly 144 | - | expression tag |
| Ser 145 | - | expression tag |
| His 146 | - | expression tag |
| Met 147 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30777.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1427.8 | |
| All* | Total formula weight | 32205.8 |
