PDB: 20505 件ウェブページステータス検索Chemie searchBIRD

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4JXH	Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH 8.5 分子名称: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide, PHOSPHATE ION 著者 Hoh, F, Rouhana, J. 登録日 2013-03-28 公開日 2013-10-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors J.Med.Chem., 56, 2013
3PGC	Crystal Structure of HLA-DR1 with CLIP106-120, flipped peptide orientation 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, HLA class II histocompatibility antigen gamma chain, ... 著者 Gunther, S, Schlundt, A, Sticht, J, Roske, Y, Heinemann, U, Wiesmuller, K.-H, Jung, G, Falk, K, Rotzschke, O, Freund, C. 登録日 2010-11-01 公開日 2010-12-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Bidirectional binding of invariant chain peptides to an MHC class II molecule. Proc.Natl.Acad.Sci.USA, 107, 2010
3PGD	Crystal Structure of HLA-DR1 with CLIP106-120, canonical peptide orientation 分子名称: HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, DR alpha chain, ... 著者 Gunther, S, Schlundt, A, Sticht, J, Roske, Y, Heinemann, U, Wiesmuller, K.-H, Jung, G, Falk, K, Rotzschke, O, Freund, C. 登録日 2010-11-01 公開日 2010-12-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Bidirectional binding of invariant chain peptides to an MHC class II molecule. Proc.Natl.Acad.Sci.USA, 107, 2010
3Q0W	ETHR From mycobacterium tuberculosis in complex with compound BDM33066 分子名称: (2S)-2-amino-3-methyl-1-{4-[3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}butan-1-one, GLYCEROL, HTH-type transcriptional regulator EthR 著者 Flipo, M, Desrose, M, Dirie, B, Carette, X, Leroux, F, Lens, Z, Rucktooa, P, Piveteau, C, Demirkaya, F, Locht, C, Villeret, V, Christophe, T, Jeon, H.K, Brodin, P, Deprez, B, Baulard, A, Willand, N. 登録日 2010-12-16 公開日 2011-12-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands. Nucleic Acids Res., 40, 2012
4JKN	Mercury Metallated Pseudomonas aeruginosa Azurin at 1.54 A 分子名称: Azurin, MERCURY (II) ION, NITRATE ION, ... 著者 Zampino, A.P, Masters, F.M, Bladholm, E.L, Berry, S.B, Panzner, M.J, Ziegler, C.J. 登録日 2013-03-10 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.536 Å) 主引用文献 Mercury metallation of the copper protein azurin and structural insight into possible heavy metal reactivity. J.Inorg.Biochem., 141, 2014
4JKY	Cobalt between two ADP's in the active site of adenylate kinase 分子名称: ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase, COBALT (II) ION 著者 Cho, Y.-J, Kern, D. 登録日 2013-03-12 公開日 2014-06-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.373 Å) 主引用文献 The energy landscape of adenylate kinase during catalysis. Nat.Struct.Mol.Biol., 22, 2015
4JLB	Crystal Structures of Adenylate kinase with 2ADP's 分子名称: ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase 著者 Cho, Y.-J, Kern, D. 登録日 2013-03-12 公開日 2014-06-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.528 Å) 主引用文献 The energy landscape of adenylate kinase during catalysis. Nat.Struct.Mol.Biol., 22, 2015
8QDF	Engineered LmrR with Met-89 replaced by para-boronophenylalanine 分子名称: Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H, Rozeboom, H.J, Longwitz, L, Leveson-Gower, R.B, Roelfes, G. 登録日 2023-08-29 公開日 2024-05-01 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Boron catalysis in a designer enzyme. Nature, 629, 2024
8QDH	Engineered LmrR carrying a cyclic boronate ester formed between Tris and p-boronophenylalanine at position 89 分子名称: GLYCEROL, Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H, Rozeboom, H.J, Longwitz, L, Leveson-Gower, R.B, Roelfes, G. 登録日 2023-08-29 公開日 2024-05-01 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Boron catalysis in a designer enzyme. Nature, 629, 2024
4JZT	Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH (E68A mutant) bound to GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, dGTP pyrophosphohydrolase 著者 Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C. 登録日 2013-04-03 公開日 2013-05-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates. Proc.Natl.Acad.Sci.USA, 110, 2013
8BVC	Solution structure of Metridium senile toxin Ms13-1 with the unique fold 分子名称: Ms13-1 著者 Mineev, K.S, Arseniev, A.S, Andreev, Y.A, Osmakov, D.I, Khasanov, T.A. 登録日 2022-12-06 公開日 2023-12-20 実験手法 SOLUTION NMR 主引用文献 Solution structure of Metridium senile toxin Ms13-1 with the unique fold To Be Published
8Q3R	Cryo-EM structure of the DNA polymerase holoenzyme E9-A20-D4 of vaccinia virus 分子名称: DNA polymerase, DNA polymerase processivity factor component OPG148, Uracil-DNA glycosylase 著者 Burmeister, W.P, Ballandras-Colas, A, Boettcher, B, Grimm, C. 登録日 2023-08-04 公開日 2024-05-08 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure and flexibility of the DNA polymerase holoenzyme of vaccinia virus. Plos Pathog., 20, 2024
4JZV	Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH bound to a non-hydrolysable triphosphorylated dinucleotide RNA (pcp-pGpG) - second guanosine residue in guanosine binding pocket 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, RNA (5'-R(*(GCP)P*G)-3'), ... 著者 Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C. 登録日 2013-04-03 公開日 2013-05-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates. Proc.Natl.Acad.Sci.USA, 110, 2013
8QAM	vaccinia virus Uracil DNA glycosidase mutant I197K-V200E-L204K 分子名称: GLYCEROL, SULFATE ION, Uracil-DNA glycosylase 著者 Tarbouriech, N, Burmeister, W.P. 登録日 2023-08-23 公開日 2024-05-08 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Structure and flexibility of the DNA polymerase holoenzyme of vaccinia virus. Plos Pathog., 20, 2024
6WMQ	Crystal Structure of Human REV-ERBbeta Ligand Binding Domain Co-Bound to Heme and NCoR ID1 Peptide 分子名称: Nuclear receptor Rev-ErbA beta variant 1, Nuclear receptor corepressor 1, PROTOPORPHYRIN IX CONTAINING FE 著者 Mosure, S.A, Shang, J, Kojetin, D.J. 登録日 2020-04-21 公開日 2021-02-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERB beta. Sci Adv, 7, 2021
3PZZ	Structure of an amyloid forming peptide GAIIGL (29-34) from amyloid beta 分子名称: Amyloid beta A4 protein 著者 Soriaga, A.B, Laganowsky, A.L, Sawaya, M.R, Eisenberg, D. 登録日 2010-12-14 公開日 2011-10-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Molecular basis for amyloid-beta polymorphism. Proc.Natl.Acad.Sci.USA, 108, 2011
6WMS	Crystal Structure of Human REV-ERBbeta Ligand Binding Domain Co-Bound to Heme and NCoR ID2 Peptide 分子名称: NCOR isoform c, Nuclear receptor Rev-ErbA beta variant 1, PROTOPORPHYRIN IX CONTAINING FE 著者 Mosure, S.A, Shang, J, Kojetin, D.J. 登録日 2020-04-21 公開日 2021-02-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERB beta. Sci Adv, 7, 2021
8A21	Crystal structure of Phosphoserine phosphatase SerB from Mycobacterium avium in complex with phenylimidazole 分子名称: 4-PHENYL-1H-IMIDAZOLE, CHLORIDE ION, GLYCEROL, ... 著者 Haufroid, M, Wouters, J. 登録日 2022-06-02 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Targeting the phosphoserine phosphatase MtSerB2 for tuberculosis drug discovery, an hybrid knowledge based /fragment based approach. Eur.J.Med.Chem., 245, 2022
8A1Z	Crystal structure of Phosphoserine phosphatase SerB from Mycobacterium avium in complex with 1-(2,4-dichlorophenyl)-3-hydroxyurea 分子名称: 1-(2,4-dichlorophenyl)-3-oxidanyl-urea, CHLORIDE ION, MAGNESIUM ION, ... 著者 Haufroid, M, Wouters, J. 登録日 2022-06-02 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Targeting the phosphoserine phosphatase MtSerB2 for tuberculosis drug discovery, an hybrid knowledge based /fragment based approach. Eur.J.Med.Chem., 245, 2022
3OY5	The crystal structure of uPA complex with peptide inhibitor MH027 at pH7.4 分子名称: MH027, SULFATE ION, Urokinase-type plasminogen activator 著者 Jiang, L.G, Andreasen, P.A, Huang, M.D. 登録日 2010-09-22 公開日 2011-08-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 The binding mechanism of a peptidic cyclic serine protease inhibitor J.Mol.Biol., 412, 2011
4GU4	Crystal structure of the T1L reovirus attachment protein sigma1 in complex with alpha-2,3-sialyllactose 分子名称: N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Outer capsid protein sigma-1 著者 Reiss, K, Stehle, T. 登録日 2012-08-29 公開日 2012-12-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 The GM2 Glycan Serves as a Functional Coreceptor for Serotype 1 Reovirus. Plos Pathog., 8, 2012
8B7T	CPSF73 CTD3 分子名称: CPSF73 著者 Thore, S, Mackereth, C. 登録日 2022-10-03 公開日 2023-05-03 最終更新日 2023-12-06 実験手法 SOLUTION NMR 主引用文献 Molecular details of the CPSF73-CPSF100 C-terminal heterodimer and interaction with Symplekin. Open Biology, 13, 2023
6W7O	Ternary complex structure - BTK cIAP compound 17 分子名称: Baculoviral IAP repeat-containing protein 2, Tyrosine-protein kinase BTK, ZINC ION, ... 著者 Calabrese, M.F, Schiemer, J.S. 登録日 2020-03-19 公開日 2020-11-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Structural Characterization of BTK:PROTAC:cIAP Ternary Complexes: From Snapshots to Ensembles Nat.Chem.Biol., 2020
6VSI	Crystal structure of FKBP12 of Candida auris 分子名称: Peptidylprolyl isomerase, SULFATE ION 著者 Li, Z, Li, H, Hernandez, G, LeMaster, D. 登録日 2020-02-11 公開日 2020-04-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Crystal structure and transient dimerization for the FKBP12 protein from the pathogenic fungus Candida auris. Biochem.Biophys.Res.Commun., 525, 2020
3OW9	Structure of an amyloid forming peptide KLVFFA from amyloid beta, alternate polymorph II 分子名称: KLVFFA hexapeptide segment from Amyloid beta 著者 Landau, M, Eisenberg, D. 登録日 2010-09-17 公開日 2011-08-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular basis for amyloid-{beta} polymorphism. Proc.Natl.Acad.Sci.USA, 108, 2011

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