6WMQ

Crystal Structure of Human REV-ERBbeta Ligand Binding Domain Co-Bound to Heme and NCoR ID1 Peptide

Summary for 6WMQ

Entry DOI	10.2210/pdb6wmq/pdb
Descriptor	Nuclear receptor Rev-ErbA beta variant 1, Nuclear receptor corepressor 1, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total)
Functional Keywords	nuclear receptor, heme-binding protein, transcription
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	51705.01
Authors	Mosure, S.A.,Shang, J.,Kojetin, D.J. (deposition date: 2020-04-21, release date: 2021-02-17, Last modification date: 2023-10-18)
Primary citation	Mosure, S.A.,Strutzenberg, T.S.,Shang, J.,Munoz-Tello, P.,Solt, L.A.,Griffin, P.R.,Kojetin, D.J. Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERB beta. Sci Adv, 7:-, 2021 Cited by PubMed: 33571111 DOI: 10.1126/sciadv.abc6479 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation