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6WMQ

Crystal Structure of Human REV-ERBbeta Ligand Binding Domain Co-Bound to Heme and NCoR ID1 Peptide

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0006355biological_processregulation of DNA-templated transcription
B0003677molecular_functionDNA binding
B0004879molecular_functionnuclear receptor activity
B0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues22
Detailsbinding site for residue HEM A 601
ChainResidue
AHIS381
APHE443
ALEU446
AMET447
AALA479
AGLY480
ALEU482
ALEU483
AMET486
AHIS568
AGLU571
ALEU382
ALEU572
APHE575
EILE2262
AVAL383
ACYS384
APRO385
AMET386
ATRP402
APHE405
APHE409

site_idAC2
Number of Residues20
Detailsbinding site for residue HEM B 601
ChainResidue
BHIS381
BLEU382
BVAL383
BCYS384
BPRO385
BMET386
BTRP402
BPHE405
BPHE409
BPHE443
BLEU446
BPHE450
BALA479
BGLY480
BLEU482
BLEU483
BMET486
BHIS568
BPHE575
BHOH707

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING:
ChainResidueDetails
ACYS384
AHIS568
BCYS384
BHIS568

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PDB entries from 2024-11-06

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