6WMS
Crystal Structure of Human REV-ERBbeta Ligand Binding Domain Co-Bound to Heme and NCoR ID2 Peptide
Summary for 6WMS
Entry DOI | 10.2210/pdb6wms/pdb |
Descriptor | Nuclear receptor Rev-ErbA beta variant 1, NCOR isoform c, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total) |
Functional Keywords | nuclear receptor, heme-binding protein, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 51240.34 |
Authors | Mosure, S.A.,Shang, J.,Kojetin, D.J. (deposition date: 2020-04-21, release date: 2021-02-17, Last modification date: 2023-10-18) |
Primary citation | Mosure, S.A.,Strutzenberg, T.S.,Shang, J.,Munoz-Tello, P.,Solt, L.A.,Griffin, P.R.,Kojetin, D.J. Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERB beta. Sci Adv, 7:-, 2021 Cited by PubMed: 33571111DOI: 10.1126/sciadv.abc6479 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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