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6WMS

Crystal Structure of Human REV-ERBbeta Ligand Binding Domain Co-Bound to Heme and NCoR ID2 Peptide

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0006355biological_processregulation of DNA-templated transcription
B0003677molecular_functionDNA binding
B0004879molecular_functionnuclear receptor activity
B0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues23
Detailsbinding site for residue HEM A 601
ChainResidue
AHIS381
AMET447
APHE450
APHE454
AALA479
AGLY480
ALEU482
ALEU483
AMET486
AHIS568
AGLU571
ALEU382
ALEU572
APHE575
AHOH724
AHOH725
AVAL383
ACYS384
APRO385
AMET386
APHE405
APHE409
ALEU446

site_idAC2
Number of Residues20
Detailsbinding site for residue HEM B 601
ChainResidue
BHIS381
BLEU382
BVAL383
BCYS384
BPRO385
BMET386
BPHE405
BPHE409
BLEU446
BPHE450
BALA479
BGLY480
BLEU482
BLEU483
BMET486
BHIS568
BGLU571
BPHE575
BHOH713
BHOH714

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING:
ChainResidueDetails
ACYS384
AHIS568
BCYS384
BHIS568

226707

PDB entries from 2024-10-30

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