8A21

Crystal structure of Phosphoserine phosphatase SerB from Mycobacterium avium in complex with phenylimidazole

Summary for 8A21

Entry DOI	10.2210/pdb8a21/pdb
Descriptor	Phosphoserine phosphatase, MAGNESIUM ION, 4-PHENYL-1H-IMIDAZOLE, ... (6 entities in total)
Functional Keywords	phosphoserine phosphatase, avium, pim, phenylimidazole, hydrolase
Biological source	Mycobacterium avium 104
Total number of polymer chains	1
Total formula weight	44292.29
Authors	Haufroid, M.,Wouters, J. (deposition date: 2022-06-02, release date: 2022-11-23, Last modification date: 2024-01-31)
Primary citation	Haufroid, M.,Volkov, A.N.,Wouters, J. Targeting the phosphoserine phosphatase MtSerB2 for tuberculosis drug discovery, an hybrid knowledge based /fragment based approach. Eur.J.Med.Chem., 245:114935-114935, 2022 Cited by PubMed: 36403421 DOI: 10.1016/j.ejmech.2022.114935 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.18 Å)

Structure validation