4JZV

Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH bound to a non-hydrolysable triphosphorylated dinucleotide RNA (pcp-pGpG) - second guanosine residue in guanosine binding pocket

Summary for 4JZV

• Entry DOI: 10.2210/pdb4jzv/pdb
• Related: 4JZS 4JZT 4JZU 4JZV
• Descriptor: RNA PYROPHOSPHOHYDROLASE, RNA (5'-R(*(GCP)P*G)-3'), MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: nudix hydrolase, rna pyrophosphohydrolase, rpph, cytosol, hydrolase-rna complex, hydrolase/rna
• Biological source: Bacillus subtilis subsp. subtilis
• Total number of polymer chains: 3
• Total formula weight: 38195.15

Authors

Piton, J.,Larue, V.,Thillier, Y.,Dorleans, A.,Pellegrini, O.,Li de la Sierra-Gallay, I.,Vasseur, J.J.,Debart, F.,Tisne, C.,Condon, C. (deposition date: 2013-04-03, release date: 2013-05-08, Last modification date: 2024-04-03)

• Primary citation: Piton, J.,Larue, V.,Thillier, Y.,Dorleans, A.,Pellegrini, O.,Li de la Sierra-Gallay, I.,Vasseur, J.J.,Debart, F.,Tisne, C.,Condon, C.; Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates.; Proc.Natl.Acad.Sci.USA, 110:8858-8863, 2013; PubMed: 23610407; DOI: 10.1073/pnas.1221510110

Experimental method

X-RAY DIFFRACTION (2.2 Å)