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4LO9
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BU of 4lo9 by Molmil
Human p53 Core Domain Mutant N235K
分子名称: Cellular tumor antigen p53, ZINC ION
著者Wallentine, B.D, Wang, Y, Luecke, H.
登録日2013-07-12
公開日2013-07-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue.
Acta Crystallogr.,Sect.D, 69, 2013
6KW5
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BU of 6kw5 by Molmil
The ClassC RSC-Nucleosome Complex
分子名称: Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ...
著者Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C.
登録日2019-09-06
公開日2020-09-09
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (10.13 Å)
主引用文献Structure of the RSC complex bound to the nucleosome
To Be Published
7X1K
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BU of 7x1k by Molmil
Crystal structure of the flagellar expression regulator DegU from Listeria monocytogenes
分子名称: Chemotaxis protein CheY
著者Oh, H.B, Lee, S, Yoon, S.I.
登録日2022-02-24
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structural and biochemical analyses of the flagellar expression regulator DegU from Listeria monocytogenes.
Sci Rep, 12, 2022
7OKQ
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BU of 7okq by Molmil
Cryo-EM Structure of the DDB1-DCAF1-CUL4A-RBX1 Complex
分子名称: Cullin-4A, DDB1- and CUL4-associated factor 1, DNA damage-binding protein 1, ...
著者Mohamed, W.I, Schenk, A.D, Kempf, G, Cavadini, S, Thoma, N.H.
登録日2021-05-18
公開日2021-10-13
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (8.4 Å)
主引用文献The CRL4 DCAF1 cullin-RING ubiquitin ligase is activated following a switch in oligomerization state.
Embo J., 40, 2021
1MI7
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BU of 1mi7 by Molmil
Crystal Structure of Domain Swapped trp Aporepressor in 30%(v/v) Isopropanol
分子名称: ISOPROPYL ALCOHOL, Trp operon repressor
著者Lawson, C.L, Benoff, B, Berger, T, Berman, H.M, Carey, J.
登録日2002-08-22
公開日2003-09-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献E. coli trp repressor forms a domain-swapped array in aqueous alcohol.
Structure, 12, 2004
4LYN
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BU of 4lyn by Molmil
Crystal structure of cyclin-dependent kinase 2 (cdk2-wt) complex with (2s)-n-(5-(((5-tert-butyl-1,3-oxazol-2-yl)methyl)sulfanyl)-1,3-thiazol-2-yl)-2-phenylpropanamide
分子名称: (2S)-N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)-2-phenylpropanamide, Cyclin-dependent kinase 2
著者Sack, J.S.
登録日2013-07-31
公開日2013-10-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of Aminothiazole Inhibitors of Cyclin-Dependent Kinase 2: Synthesis, X-Ray Crystallographic Analysis, and Biological Activities
J.Med.Chem., 45, 2002
3C28
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BU of 3c28 by Molmil
Crystal structure of the product synapse complex
分子名称: LoxP DNA, chain C, chain D, ...
著者Ghosh, K, Van Duyne, G.D.
登録日2008-01-24
公開日2009-02-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Detailed study on Synapsis in Cre-loxP recombination reaction
To be Published
6UD7
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BU of 6ud7 by Molmil
Crystal structure of full-length human DCAF15-DDB1(deltaBPB)-DDA1-RBM39 in complex with indisulam
分子名称: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1,DNA damage-binding protein 1, ...
著者Bussiere, D.E, Shu, W, Xie, L, Knapp, M.
登録日2019-09-18
公開日2019-12-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat.Chem.Biol., 16, 2020
4LZ1
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BU of 4lz1 by Molmil
X-ray structure of the complex between human thrombin and the TBA deletion mutant lacking thymine 12 nucleobase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, ...
著者Pica, A, Russo Krauss, I, Merlino, A, Sica, F.
登録日2013-07-31
公開日2014-01-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer.
Febs J., 280, 2013
6UE5
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BU of 6ue5 by Molmil
Crystal structure of full-length human DCAF15-DDB1-deltaPBP-DDA1-RBM39 in complex with 4-(aminomethyl)-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide
分子名称: 4-(aminomethyl)-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, ...
著者Knapp, M.S, Shu, W, Xie, L, Bussiere, D.E.
登録日2019-09-20
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat.Chem.Biol., 16, 2020
8D5V
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BU of 8d5v by Molmil
WhiB6 bound to the SigmaAr4-RNAP Beta flap tip chimera
分子名称: IRON/SULFUR CLUSTER, Probable transcriptional regulator WhiB6, RNA polymerase sigma factor SigA,DNA-directed RNA polymerase subunit beta
著者Wan, T, Zhang, L.M.
登録日2022-06-06
公開日2023-06-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of WhiB6 and SigA4-betaTip complex
To Be Published
1LX8
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BU of 1lx8 by Molmil
Regulation of directionality in bacteriophage lambda site-specific recombination: structure of the Xis protein
分子名称: Excisionase
著者Sam, M.D, Papagiannis, C, Connolly, K.M, Corselli, L, Iwahara, J, Lee, J, Phillips, M, Wojciak, J.M, Johnson, R.C, Clubb, R.T.
登録日2002-06-04
公開日2003-06-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Regulation of directionality in bacteriophage lambda site-specific recombination: structure of the Xis protein
J.Mol.Biol., 324, 2002
7XAQ
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BU of 7xaq by Molmil
Cryo-EM structure of PvrA-DNA complex
分子名称: Probable transcriptional regulator, fadD1
著者Zhu, Y.B, Su, Z.M, Bao, R.
登録日2022-03-18
公開日2023-04-26
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献The Pseudomonas aeruginosa regulator PvrA binds cooperatively to multiple pseudo-palindromic sites to efficiently stimulate target gene
To be published
3KP4
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BU of 3kp4 by Molmil
Staphylococcus epidermidis TcaR in complex with methicillin
分子名称: Transcriptional regulator TcaR, methicillin
著者Chang, Y.M, Chen, C.K, Wang, A.H.
登録日2009-11-15
公開日2010-06-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KP5
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BU of 3kp5 by Molmil
Staphylococcus epidermidis TcaR in complex with kanamycin
分子名称: KANAMYCIN A, Transcriptional regulator TcaR
著者Chang, Y.M, Chen, C.K, Wang, A.H.
登録日2009-11-15
公開日2010-06-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KP6
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BU of 3kp6 by Molmil
Staphylococcus epidermidis TcaR in complex with salicylate
分子名称: 2-HYDROXYBENZOIC ACID, CACODYLATE ION, Transcriptional regulator TcaR
著者Chang, Y.M, Chen, C.K, Yeh, Y.J, Wang, A.H.
登録日2009-11-15
公開日2010-09-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis.
Proc.Natl.Acad.Sci.USA, 107, 2010
6O5C
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BU of 6o5c by Molmil
X-ray crystal structure of metal-dependent transcriptional regulator MtsR
分子名称: DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, Putative metal-dependent transcriptional regulator
著者Do, H, Kumaraswami, M.
登録日2019-03-01
公開日2019-06-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence.
Nucleic Acids Res., 47, 2019
3BP8
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BU of 3bp8 by Molmil
Crystal structure of Mlc/EIIB complex
分子名称: ACETATE ION, PTS system glucose-specific EIICB component, Putative NAGC-like transcriptional regulator, ...
著者An, Y.J, Jung, H.I, Cha, S.S.
登録日2007-12-18
公開日2008-05-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Analyses of Mlc-IIBGlc interaction and a plausible molecular mechanism of Mlc inactivation by membrane sequestration
Proc.Natl.Acad.Sci.Usa, 105, 2008
9JA1
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BU of 9ja1 by Molmil
The RNA polymerase II elongation complex from Saccharomyces cerevisiae
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*GP*CP*TP*CP*CP*TP*TP*CP*TP*CP*CP*CP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*T)-3'), DNA (5'-D(P*TP*GP*GP*GP*AP*GP*AP*AP*GP*GP*AP*GP*C)-3'), ...
著者Yi, G, Ma, J, Zhang, P.
登録日2024-08-23
公開日2024-09-04
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献The RNA polymerase II elongation complex from Saccharomyces cerevisiae
To Be Published
3SXY
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BU of 3sxy by Molmil
Metal-free full-length structure of Tm0439, a metal-binding FCD family transcriptional regulator
分子名称: Transcriptional regulator, GntR family
著者Czelakowski, G.P, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI)
登録日2011-07-15
公開日2011-11-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.647 Å)
主引用文献Metal-free full-length structure of Tm0439, a metal-binding FCD family transcriptional regulator
To be Published
4LZ4
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BU of 4lz4 by Molmil
X-ray structure of the complex between human thrombin and the TBA deletion mutant lacking thymine 3 nucleobase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, ...
著者Pica, A, Russo Krauss, I, Merlino, A, Sica, F.
登録日2013-07-31
公開日2014-01-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer.
Febs J., 280, 2013
6DK4
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BU of 6dk4 by Molmil
Crystal structure of Campylobacter jejuni peroxide stress regulator
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Ferric uptake regulation protein, MANGANESE (II) ION, ...
著者Sarvan, S, Brunzelle, J.S, Couture, J.F.
登録日2018-05-28
公開日2018-06-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Crystal structure of Campylobacter jejuni peroxide regulator.
FEBS Lett., 592, 2018
5LM9
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BU of 5lm9 by Molmil
Structure of E. coli NusA
分子名称: MAGNESIUM ION, SULFATE ION, Transcription termination/antitermination protein NusA
著者Said, N, Weber, G, Santos, K, Wahl, M.C.
登録日2016-07-29
公開日2017-04-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.143 Å)
主引用文献Structural basis for lambda N-dependent processive transcription antitermination.
Nat Microbiol, 2, 2017
6L87
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BU of 6l87 by Molmil
Solution structure of the tandem PWWP-ARID domains of human RBBP1
分子名称: AT-rich interactive domain-containing protein 4A
著者Gong, W.B, Perrett, S, Feng, Y.G.
登録日2019-11-05
公開日2021-01-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural insight into chromatin recognition by multiple domains of the tumor suppressor RBBP1.
J.Mol.Biol., 2021
3KQK
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BU of 3kqk by Molmil
Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
分子名称: 5'-D(*TP*TP*TP*TP*TP*T)-3', Serine protease/NTPase/helicase NS3
著者Gu, M, Rice, C.M.
登録日2009-11-17
公開日2010-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism.
Proc.Natl.Acad.Sci.USA, 107, 2010

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