4LO9

Human p53 Core Domain Mutant N235K

Replaces:  2QXB

Summary for 4LO9

• Entry DOI: 10.2210/pdb4lo9/pdb
• Related: 4KVP 4LOE 4LOF
• Descriptor: Cellular tumor antigen p53, ZINC ION (3 entities in total)
• Functional Keywords: beta sandwich, tumor suppressor, dna binding, nuclear, apoptosis
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 98669.46

Authors

Wallentine, B.D.,Wang, Y.,Luecke, H. (deposition date: 2013-07-12, release date: 2013-07-31, Last modification date: 2023-09-20)

• Primary citation: Wallentine, B.D.,Wang, Y.,Tretyachenko-Ladokhina, V.,Tan, M.,Senear, D.F.,Luecke, H.; Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue.; Acta Crystallogr.,Sect.D, 69:2146-2156, 2013; PubMed: 24100332; DOI: 10.1107/S0907444913020830

Experimental method

X-RAY DIFFRACTION (2.5 Å)