PDB: 223790 件ウェブページステータス検索Chemie searchBIRD

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4G4M	Crystal structure of the de novo designed fluorinated peptide alpha4F3(6-13) 分子名称: 1,2-ETHANEDIOL, TETRAETHYLENE GLYCOL, alpha4F3(6-13) 著者 Buer, B.C, Meagher, J.L, Stuckey, J.A, Marsh, E.N.G. 登録日 2012-07-16 公開日 2012-10-31 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Comparison of the structures and stabilities of coiled-coil proteins containing hexafluoroleucine and t-butylalanine provides insight into the stabilizing effects of highly fluorinated amino acid side-chains. Protein Sci., 21, 2012
4G2W	Crystal structure of PDE5A in complex with its inhibitor 分子名称: 5,6-diethyl-2-{5-[(4-methylpiperazin-1-yl)sulfonyl]-2-propoxyphenyl}pyrimidin-4(3H)-one, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Ren, J, Chen, T.T, Xu, Y.C. 登録日 2012-07-13 公開日 2013-06-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Design, synthesis, and pharmacological evaluation of monocyclic pyrimidinones as novel inhibitors of PDE5. J.Med.Chem., 55, 2012
4G68	Biochemical and structural insights into xylan utilization by the thermophilic bacteriumcaldanaerobius polysaccharolyticus 分子名称: ABC transporter, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-xylopyranose 著者 Agarwal, V, Nair, S.K. 登録日 2012-07-18 公開日 2012-08-22 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Biochemical and Structural Insights into Xylan Utilization by the Thermophilic Bacterium Caldanaerobius polysaccharolyticus. J.Biol.Chem., 287, 2012
4G5J	Crystal structure of EGFR kinase in complex with BIBW2992 分子名称: (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide, Epidermal growth factor receptor, N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamide 著者 Solca, F, Dahl, G, Zoephel, A, Bader, G, Sanderson, M, Klein, C, Kraemer, O, Himmelsbach, F, Haaksma, E, Adolf, G.R. 登録日 2012-07-18 公開日 2012-08-29 最終更新日 2012-10-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Target Binding Properties and Cellular Activity of Afatinib (BIBW 2992), an Irreversible ErbB Family Blocker. J.Pharmacol.Exp.Ther., 343, 2012
4GBD	Crystal Structure Of Adenosine Deaminase From Pseudomonas Aeruginosa Pao1 with bound Zn and methylthio-coformycin 分子名称: (8R)-3-(5-S-methyl-5-thio-beta-D-ribofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol, PHOSPHATE ION, Putative uncharacterized protein, ... 著者 Ho, M, Guan, R, Almo, S.C, Schramm, V.L. 登録日 2012-07-27 公開日 2013-06-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.975 Å) 主引用文献 Methylthioadenosine deaminase in an alternative quorum sensing pathway in Pseudomonas aeruginosa. Biochemistry, 51, 2012
3PE5	Three-dimensional Structure of protein A7VV38_9CLOT from Clostridium leptum DSM 753, Northeast Structural Genomics Consortium Target QlR103 分子名称: Uncharacterized protein 著者 Kuzin, A, Su, M, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2010-10-25 公開日 2010-11-10 最終更新日 2012-02-22 実験手法 X-RAY DIFFRACTION (2.381 Å) 主引用文献 Northeast Structural Genomics Consortium Target QlR103 To be published
4G84	Crystal structure of human HisRS 分子名称: CHLORIDE ION, Histidine--tRNA ligase, cytoplasmic, ... 著者 Wei, Z, Wu, J, Zhou, J.J, Yang, X.-L, Zhang, M, Schimmel, P. 登録日 2012-07-21 公開日 2012-09-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing. Structure, 20, 2012
4G8R	Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1 分子名称: (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), Plasminogen activator inhibitor-1, SULFATE ION 著者 Stuckey, J.A, Lawrence, D.A, Li, S.-H. 登録日 2012-07-23 公開日 2013-12-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1. Proc.Natl.Acad.Sci.USA, 110, 2013
4GDA	Circular Permuted Streptavidin A50/N49 分子名称: BIOTIN, ETHANOL, GLYCEROL, ... 著者 Le Trong, I, Chu, V, Xing, Y, Lybrand, T.P, Stayton, P.S, Stenkamp, R.E. 登録日 2012-07-31 公開日 2013-06-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Structural consequences of cutting a binding loop: two circularly permuted variants of streptavidin. Acta Crystallogr.,Sect.D, 69, 2013
4G9H	Crystal structure of glutahtione s-transferase homolog from yersinia pestis, target EFI-501894, with bound glutathione 分子名称: GLUTATHIONE, GLYCEROL, Glutathione S-transferase 著者 Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2012-07-23 公開日 2012-08-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of glutahtione s-transferase homolog from yersinia pestis, target efi-501894, with bound glutathione To be Published
4GF0	Crystal structure of glutahtione transferase homolog from sulfitobacter, TARGET EFI-501084, with bound glutathione 分子名称: CHLORIDE ION, GLUTATHIONE, Glutathione S-transferase 著者 Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2012-08-02 公開日 2012-08-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of glutahtione transferase homolog from sulfitobacter, TARGET EFI-501084, with bound glutathione To be Published
3MER	Crystal Structure of the methyltransferase Slr1183 from Synechocystis sp. PCC 6803, Northeast Structural Genomics Consortium Target SgR145 分子名称: Slr1183 protein 著者 Seetharaman, J, Chen, Y, Forouhar, F, Rossi, P, Sahdev, S, Xiao, R, Ciccosanti, C, Foote, E.L, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2010-03-31 公開日 2010-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Northeast Structural Genomics Consortium Target SgR145 To be Published
4GI0	Crystal structure of CD23 lectin domain mutant E249A 分子名称: GLYCEROL, Low affinity immunoglobulin epsilon Fc receptor 著者 Yuan, D, Sutton, B.J, Dhaliwal, B. 登録日 2012-08-08 公開日 2013-06-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E. J.Biol.Chem., 288, 2013
4FSJ	Crystal structure of the virus like particle of Flock House virus 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... 著者 Speir, J.A, Chen, Z, Reddy, V.S, Johnson, J.E. 登録日 2012-06-27 公開日 2012-08-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural study of virus assembly intermediates reveals maturation event sequence and a staging position for externalized lytic peptides to be published, 2012
4FT3	Crystal Structure of the CHK1 分子名称: 1-(5-chloro-2,4-dimethoxyphenyl)-3-pyrazin-2-ylurea, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FTG	The crystal structure of an AHNAK peptide in complex with the S100A10/AnxA2 heterotetramer 分子名称: Annexin A2, ISOPROPYL ALCOHOL, Neuroblast differentiation-associated protein AHNAK, ... 著者 Ozorowski, G, Luecke, H. 登録日 2012-06-27 公開日 2013-01-02 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.5054 Å) 主引用文献 Structure of a C-terminal AHNAK peptide in a 1:2:2 complex with S100A10 and an acetylated N-terminal peptide of annexin A2. Acta Crystallogr.,Sect.D, 69, 2013
4GKP	Structure of the truncated neck and C-terminal motor homology domain of ViK1 from Candida glabrata 分子名称: Spindle pole body-associated protein VIK1 著者 Duan, D, Allingham, J.S. 登録日 2012-08-13 公開日 2012-10-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Neck Rotation and Neck Mimic Docking in the Noncatalytic Kar3-associated Protein Vik1. J.Biol.Chem., 287, 2012
4FUN	Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms 分子名称: Accumulation associated protein, THIOCYANATE ION, ZINC ION 著者 Conrady, D.G, Wilson, J.J, Herr, A.B. 登録日 2012-06-28 公開日 2013-01-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms. Proc.Natl.Acad.Sci.USA, 110, 2013
1YHH	Uncyclized precursor structure of S65A Y66S G67A GFP variant 分子名称: green fluorescent protein 著者 Barondeau, D.P, Kassmann, C.J, Tainer, J.A, Getzoff, E.D. 登録日 2005-01-07 公開日 2005-02-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Understanding GFP Chromophore Biosynthesis: Controlling Backbone Cyclization and Modifying Post-translational Chemistry. Biochemistry, 44, 2005
4FV5	Crystal Structure of the ERK2 complexed with EK9 分子名称: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, N-[(1S)-2-hydroxy-1-phenylethyl]-4-(5-methyl-2-phenylpyrimidin-4-yl)-1H-pyrrole-2-carboxamide, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-29 公開日 2012-08-29 最終更新日 2014-09-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the ERK2 complexed with EK9 TO BE PUBLISHED
4GM0	Crystal Structure of Benzoylformate Decarboxylase Mutant L403N 分子名称: 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Benzoylformate decarboxylase, CALCIUM ION, ... 著者 Novak, W.R.P, Andrews, F.H, Tom, A.R, Gunderman, P.R, McLeish, M.J. 登録日 2012-08-15 公開日 2013-05-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 A bulky hydrophobic residue is not required to maintain the v-conformation of enzyme-bound thiamin diphosphate. Biochemistry, 52, 2013
3MAR	Crystal structure of homodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP 分子名称: Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Yang, B, Peng, Y, Ding, J. 登録日 2010-03-24 公開日 2010-11-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.41 Å) 主引用文献 Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H. Cell Res., 20, 2010
4FSM	Crystal Structure of the CHK1 分子名称: 4-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenol, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FT9	Crystal Structure of the CHK1 分子名称: 1-(5-cyanopyrazin-2-yl)-3-isoquinolin-3-ylurea, SULFATE ION, Serine/threonine-protein kinase Chk1 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FTK	Crystal Structure of the CHK1 分子名称: 3-(4'-hydroxybiphenyl-4-yl)-2,4-dihydroindeno[1,2-c]pyrazol-6-ol, ISOPROPYL ALCOHOL, SULFATE ION, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of the CHK1 To be Published

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