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4G4M

Crystal structure of the de novo designed fluorinated peptide alpha4F3(6-13)

Summary for 4G4M
Entry DOI10.2210/pdb4g4m/pdb
Related3TWE 3TWF 3TWG 4G3B 4G4L
Descriptoralpha4F3(6-13), TETRAETHYLENE GLYCOL, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsalpha helix, de novo designed, fluorinated protein, coiled-coil, de novo protein
Total number of polymer chains2
Total formula weight7755.82
Authors
Buer, B.C.,Meagher, J.L.,Stuckey, J.A.,Marsh, E.N.G. (deposition date: 2012-07-16, release date: 2012-10-31, Last modification date: 2017-11-15)
Primary citationBuer, B.C.,Meagher, J.L.,Stuckey, J.A.,Marsh, E.N.
Comparison of the structures and stabilities of coiled-coil proteins containing hexafluoroleucine and t-butylalanine provides insight into the stabilizing effects of highly fluorinated amino acid side-chains.
Protein Sci., 21:1705-1715, 2012
Cited by
PubMed: 22930450
DOI: 10.1002/pro.2150
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.48 Å)
Structure validation

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