PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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6T2C	Bat Influenza A polymerase recycling complex 分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Wandzik, J.M, Kouba, T, Cusack, S. 登録日 2019-10-08 公開日 2020-04-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.52 Å) 主引用文献 A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
1MWH	REOVIRUS POLYMERASE LAMBDA3 BOUND TO MRNA CAP ANALOG 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, MANGANESE (II) ION, MINOR CORE PROTEIN LAMBDA 3 著者 Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C. 登録日 2002-09-29 公開日 2002-12-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 RNA Synthesis in a Cage-Structural Studies of Reovirus Polymerase lambda3 Cell(Cambridge,Mass.), 111, 2002
7EKJ	Crystals structure of classical swine fever virus NS5B (residues 91-694) 分子名称: Classical swine fever virus NS5B 著者 Liu, W, Gong, P. 登録日 2021-04-05 公開日 2021-07-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.06 Å) 主引用文献 An induced-fit de novo initiation mechanism suggested by a pestivirus RNA-dependent RNA polymerase. Nucleic Acids Res., 49, 2021
6XEZ	Structure of SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ... 著者 Chen, J, Malone, B, Llewellyn, E.C, Campbell, E.A, Darst, S.A. 登録日 2020-06-14 公開日 2020-07-29 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex. Cell, 182, 2020
5MDT	Structure of the CTD-interacting domain (CID) of Seb1 from S. pombe. 分子名称: Rpb7-binding protein seb1 著者 Wittmann, S, Renner, M, Vasiljeva, L, Grimes, J. 登録日 2016-11-13 公開日 2017-04-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Nat Commun, 8, 2017
6CUX	Escherichia coli RpoB S531L mutant RNA polymerase holoenzyme in complex with Kanglemycin A 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Molodtsov, V, Murakami, K.S. 登録日 2018-03-26 公開日 2018-07-25 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (4.104 Å) 主引用文献 Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin-Resistant Mycobacterium tuberculosis. Mol. Cell, 72, 2018
7ELA	Structure of Lassa virus polymerase in complex with 3'-vRNA and Z mutant (F36A) 分子名称: 3-'vRNA promoter, MANGANESE (II) ION, RING finger protein Z, ... 著者 Xu, X, Peng, R, Peng, Q, Shi, Y. 登録日 2021-04-09 公開日 2021-05-05 最終更新日 2021-07-14 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals. Nat Microbiol, 6, 2021
7EL9	Structure of Machupo virus L polymerase in complex with Z protein and 3'-vRNA (dimeric complex) 分子名称: MANGANESE (II) ION, Machupo virus 3'-vRNA promoter, RING finger protein Z, ... 著者 Peng, R, Xu, X, Peng, Q, Shi, Y. 登録日 2021-04-09 公開日 2021-05-05 最終更新日 2021-07-14 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals. Nat Microbiol, 6, 2021
6PLN	X-ray crystal structure of Pyrococcus furiosus general transcription factor TFE-alpha 分子名称: Transcription factor E 著者 Murakami, K.S, Jun, S.H. 登録日 2019-07-01 公開日 2020-07-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase. Nat Commun, 11, 2020
6FLQ	CryoEM structure of E.coli RNA polymerase paused elongation complex bound to NusA 分子名称: DNA (31-MER), DNA (39-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Guo, X, Weixlbaumer, A. 登録日 2018-01-26 公開日 2018-03-21 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural Basis for NusA Stabilized Transcriptional Pausing. Mol. Cell, 69, 2018
5VSW	X-ray crystal structure of Escherichia coli RNA polymerase and DksA/ppGpp complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Murakami, K.S, Molodtsov, V. 登録日 2017-05-12 公開日 2017-06-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (4.295 Å) 主引用文献 Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA. Mol. Cell, 69, 2018
5W1T	X-ray crystal structure of Escherichia coli RNA polymerase and DksA complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Murakami, K.S, Molodtsov, V. 登録日 2017-06-04 公開日 2017-06-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA. Mol. Cell, 69, 2018
7ELC	Structure of monomeric complex of MACV L bound to Z and 3'-vRNA 分子名称: 3'-vRNA promoter, MANGANESE (II) ION, RING finger protein Z, ... 著者 Xu, X, Peng, R, Peng, Q, Shi, Y. 登録日 2021-04-09 公開日 2021-05-05 最終更新日 2021-07-14 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals. Nat Microbiol, 6, 2021
6CUU	Thermus thermophiles RNA polymerase in complex with promoter DNA and antibiotic Kanglemycin A 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*CP*TP*CP*TP*GP*AP*TP*GP*CP*A)-3'), DNA (5'-D(P*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Molodtsov, V, Murakami, K.S. 登録日 2018-03-26 公開日 2018-07-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.994 Å) 主引用文献 Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin-Resistant Mycobacterium tuberculosis. Mol. Cell, 72, 2018
6TU5	Influenza A/H7N9 polymerase core (apo) 分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Cusack, S, Pflug, A. 登録日 2020-01-02 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.325 Å) 主引用文献 A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
5OHO	Crystal structure of the KOWx-KOW4 domain of human DSIF 分子名称: CHLORIDE ION, GLYCEROL, Transcription elongation factor SPT5 著者 Bernecky, C, Plitzko, J.M, Cramer, P. 登録日 2017-07-17 公開日 2017-09-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. Nat. Struct. Mol. Biol., 24, 2017
8KDB	Cryo-EM structure of the human parainfluenza virus hPIV3 L-P polymerase in dimeric form 分子名称: MAGNESIUM ION, Phosphoprotein, RNA-directed RNA polymerase L, ... 著者 Xie, J, Wang, L, Zhai, G, Wu, D, Lin, Z, Wang, M, Yan, X, Gao, L, Huang, X, Fearns, R, Chen, S. 登録日 2023-08-09 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural basis for dimerization of a paramyxovirus polymerase complex. Nat Commun, 15, 2024
8KDC	Cryo-EM structure of the human parainfluenza virus hPIV3 L-P polymerase in monomeric form 分子名称: MAGNESIUM ION, Phosphoprotein, RNA-directed RNA polymerase L, ... 著者 Xie, J, Wang, L, Zhai, G, Wu, D, Lin, Z, Wang, M, Yan, X, Gao, L, Huang, X, Fearns, R, Chen, S. 登録日 2023-08-09 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis for dimerization of a paramyxovirus polymerase complex. Nat Commun, 15, 2024
7ELB	Structure of Machupo virus L polymerase in complex with Z protein (dimeric form) 分子名称: MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ... 著者 Peng, R, Xu, X, Peng, Q, Shi, Y. 登録日 2021-04-09 公開日 2021-05-05 最終更新日 2021-07-14 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals. Nat Microbiol, 6, 2021
8PDY	E. coli RNA polymerase paused at ops site 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. 登録日 2023-06-13 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
8PH9	E. coli RNA polymerase paused at ops site (non-complementary scaffold) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. 登録日 2023-06-19 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
4KBM	Structure of the Mtb CarD/RNAP Beta subunit B1-B2 domains complex 分子名称: DNA-directed RNA polymerase subunit beta, RNA polymerase-binding transcription factor CarD 著者 Gulten, G, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2013-04-23 公開日 2013-10-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1146 Å) 主引用文献 Structure of the Mtb CarD/RNAP beta-Lobes Complex Reveals the Molecular Basis of Interaction and Presents a Distinct DNA-Binding Domain for Mtb CarD. Structure, 21, 2013
6KUU	Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B3) 分子名称: 3'-vRNA, 5'-vRNA, Polymerase 3, ... 著者 Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. 登録日 2019-09-02 公開日 2019-12-11 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B3) To Be Published
6IPJ	Binary Complex of Human DNA Polymerase Mu with MndTTP 分子名称: DNA-directed DNA/RNA polymerase mu,DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, SULFATE ION, ... 著者 Chang, Y.K, Wu, W.J, Tsai, M.D. 登録日 2018-11-03 公開日 2019-05-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
4LQ9	Crystal structure of human norovirus RNA-dependent RNA-polymerase in complex with NAF2 分子名称: MAGNESIUM ION, RNA-dependent RNA-polymerase, naphthalene-1,5-disulfonic acid 著者 Milani, M, Tarantino, D, Mastrangelo, E, Croci, R. 登録日 2013-07-17 公開日 2014-02-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase. Antiviral Res., 102, 2014

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