6XEZ

Structure of SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC

Summary for 6XEZ

EMDB information22160 22270 22271
Descriptornsp12, nsp8, nsp7, ... (11 entities in total)
Functional Keywordsrna-dependent rna polymerase, viral replication-transcription complex, transcription, viral proteins, transferase-hydrolase-rna complex, transferase/hydrolase/rna
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains8
Total molecular weight327962.36
Authors
Chen, J.,Malone, B.,Llewellyn, E.C.,Campbell, E.A.,Darst, S.A. (deposition date: 2020-06-14, release date: 2020-07-29, Last modification date: 2020-08-05)
Primary citation
Chen, J.,Malone, B.,Llewellyn, E.,Grasso, M.,Shelton, P.M.M.,Olinares, P.D.B.,Maruthi, K.,Eng, E.T.,Vatandaslar, H.,Chait, B.,Kapoor, T.,Darst, S.A.,Campbell, E.A.
Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex.
Biorxiv, 2020
PubMed: 32676607 (PDB entries with the same primary citation)
DOI: 10.1101/2020.07.08.194084
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone20 0.1% 9.6% 0.65MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload
167518
PDB entries from 2020-08-12