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4D3C
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Crystal structure of the NK1 domain of HGF in complex with anti-HGF monoclonal antibody SFN68.
分子名称: HEPATOCYTE GROWTH FACTOR, SFN68 FAB
著者Kang, Y.J, Kim, K.L, Cho, H.S, Chung, J.H.
登録日2014-10-21
公開日2016-01-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist.
to be published
4G8G
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Crystal Structure of C12C TCR-HA B2705-KK10
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27 alpha chain, ...
著者Gras, S, Wilmann, P.G, Rossjohn, J.
登録日2012-07-23
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells.
Immunity, 38, 2013
4F7M
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Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009 H1N1 PA (649-658)
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
著者Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, George, F.G.
登録日2012-05-16
公開日2012-10-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals.
J.Virol., 86, 2012
4G43
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Structure of the chicken MHC class I molecule BF2*0401 complexed to P5E
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 8-MERIC PEPTIDE P5E, Beta-2 microglobulin, ...
著者Zhang, J, Chen, Y, Qi, J, Gao, F, Liu, J, Kaufman, J, Xia, C, Gao, G.F.
登録日2012-07-16
公開日2012-11-21
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens.
J.Immunol., 189, 2012
4G9D
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Crystal Structure of HLA B2705-KK10
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Gras, S, Wilmann, P.G, Rossjohn, J.
登録日2012-07-23
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells.
Immunity, 38, 2013
4GKN
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A2-MHC Complex carrying FATGIGIITV
分子名称: Beta-2-microglobulin, FAT Cognate peptide, MHC class I antigen, ...
著者Sewell, A.K, Rizkallah, P.J, Cole, D.K, Wooldridge, L, Price, D.A.
登録日2012-08-13
公開日2012-09-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.753 Å)
主引用文献T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting.
J.Biol.Chem., 287, 2012
4F37
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Structure of the tethered N-terminus of Alzheimer's disease A peptide
分子名称: Colicin-E7 immunity protein, Fab WO2 anti-amyloid-beta antibody Fab fragment, Im7 immunity protein
著者Nisbet, R.M, Nuttall, S.D, Caine, J.M, Rober, R, Hittaki, M, Pearce, L.A, Davydova, N, Masters, C.L, Varghese, J.N, Streltsov, V.A.
登録日2012-05-09
公開日2013-05-15
最終更新日2014-09-03
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-beta peptide.
Proteins, 81, 2013
4GRL
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Crystal structure of a autoimmune TCR-MHC complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DQ-alpha chain, MHC class II antigen, ...
著者Sethi, D.K, Wucherpfennig, K.W.
登録日2012-08-25
公開日2013-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop.
Nat Commun, 4, 2013
4FQX
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Crystal structure of HLA-DM bound to HLA-DR1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DM alpha chain, ...
著者Sethi, D.K, Pos, W, Wucherpfennig, K.W.
登録日2012-06-25
公開日2013-01-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.599 Å)
主引用文献Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection.
Cell(Cambridge,Mass.), 151, 2012
4F7P
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Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009H1N1 PB1 (496-505)
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
著者Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, Gao, G.F.
登録日2012-05-16
公開日2012-10-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals.
J.Virol., 86, 2012
4GUP
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Structure of MHC-class I related molecule MR1
分子名称: 2-amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde, Beta-2-microglobulin, CHLORIDE ION, ...
著者Patel, O, Le Nours, J, Rossjohn, J.
登録日2012-08-29
公開日2012-10-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献MR1 presents microbial vitamin B metabolites to MAIT cells
Nature, 491, 2012
4H1L
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TCR interaction with peptide mimics of nickel offers structural insights in nickel contact allergy
分子名称: Ani2.3 TCR A chain, Ani2.3 TCR B chain, HLA class II histocompatibility antigen, ...
著者Kappler, J.W, Yin, L, Dai, S, Marrack, P.
登録日2012-09-10
公開日2012-11-14
最終更新日2013-09-04
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy.
Proc.Natl.Acad.Sci.USA, 109, 2012
4H26
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TCR interaction with peptide mimics of nickel offers structure insight to nickel contact allergy
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ...
著者Kappler, J.W, Yin, L, Dai, S, Marrack, P, Crawford, F.
登録日2012-09-12
公開日2013-10-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy.
Proc.Natl.Acad.Sci.USA, 109, 2012
3GSU
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Crystal structure of the binary complex between HLA-A2 and HCMV NLV-M5T peptide variant
分子名称: Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant M5T (NLVPTVATV), ...
著者Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D.
登録日2009-03-27
公開日2009-08-04
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope.
J.Immunol., 183, 2009
3GSN
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Crystal structure of the public RA14 TCR in complex with the HCMV dominant NLV/HLA-A2 epitope
分子名称: Beta-2-microglobulin, CHLORIDE ION, HCMV pp65 fragment 495-503 (NLVPMVATV), ...
著者Gras, S, Saulquin, X, Reiser, J.-B, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D.
登録日2009-03-27
公開日2009-08-04
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope.
J.Immunol., 183, 2009
3GSW
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Crystal structure of the binary complex between HLA-A2 and HCMV NLV-T8A peptide variant
分子名称: Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant T8A (NLVPMVAAV), ...
著者Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D.
登録日2009-03-27
公開日2009-08-04
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope.
J.Immunol., 183, 2009
3GSR
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Crystal structure of the binary complex between HLA-A2 and HCMV NLV-M5V peptide variant
分子名称: Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant M5V (NLVPVVATV), ...
著者Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D.
登録日2009-03-27
公開日2009-08-04
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope.
J.Immunol., 183, 2009
3GSV
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Crystal structure of the binary complex between HLA-A2 and HCMV NLV-M5Q peptide variant
分子名称: Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant M5Q (NLVPQVATV), ...
著者Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D.
登録日2009-03-27
公開日2009-08-04
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope.
J.Immunol., 183, 2009
3H7B
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Human Class I MHC HLA-A2 in complex with the Tel1p peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2009-04-24
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
3H9H
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Human Class I MHC HLA-A2(A150P) in complex with the Tel1p peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2009-04-30
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
3HAE
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Rational development of high-affinity T-cell receptor-like antibodies
分子名称: Antibody heavy chain, Antibody light chain, Beta-2-microglobulin, ...
著者Stewart-Jones, G, Wadle, A, Hombach, A, Shenderov, E, Held, G, Fischer, E.
登録日2009-05-01
公開日2009-05-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Rational development of high-affinity T-cell receptor-like antibodies
Proc.Natl.Acad.Sci.USA, 106, 2009
3HCV
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Crystal structure of HLA-B*2709 complexed with the double citrullinated vasoactive intestinal peptide type 1 receptor (VIPR) peptide (residues 400-408)
分子名称: Beta-2-microglobulin, DOUBLE CITRULLINATED VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR, HLA class I histocompatibility antigen, ...
著者Beltrami, A, Gabdulkhakov, A, Rossmann, M, Ziegler, A, Uchanska-Ziegler, B, Saenger, W.
登録日2009-05-06
公開日2009-06-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Citrullination-and mhc polymorphism-dependent conformational changes of a self peptide
To be Published
3HI1
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Structure of HIV-1 gp120 (core with V3) in Complex with CD4-Binding-Site Antibody F105
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, F105 Heavy Chain, F105 Light Chain, ...
著者Kwon, Y.D, Chen, L, Zhou, T, Wu, X, O'Dell, S, Cavacini, L, Hessell, A.J, Pancera, M, Tang, M, Xu, L, Yang, Z, Zhang, M.-Y, Arthos, J, Burton, D.R, Dimitrov, D, Nabel, G.J, Posner, M, Sodroski, J, Wyatt, R, Mascola, J.R, Kwong, P.D.
登録日2009-05-18
公開日2009-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science, 326, 2009
3HG1
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Germline-governed recognition of a cancer epitope by an immunodominant human T cell receptor
分子名称: Beta-2-microglobulin, CANCER/MART-1, GLYCEROL, ...
著者Cole, D.K, Yuan, F, Rizkallah, P.J, Miles, J.J, Gostick, E, Price, D.A, Gao, G.F, Jakobsen, B.K, Sewell, A.K.
登録日2009-05-13
公開日2009-07-28
最終更新日2014-04-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor.
J.Biol.Chem., 284, 2009
3IU3
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Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain
分子名称: Heavy chain of Fab fragment of Basiliximab, Interleukin-2 receptor alpha chain, Light chain of Fab fragment of Basiliximab, ...
著者Du, J, Yang, H, Wang, J, Ding, J.
登録日2009-08-29
公開日2010-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for the blockage of IL-2 signaling by therapeutic antibody basiliximab
J.Immunol., 184, 2010

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