4FQX
Crystal structure of HLA-DM bound to HLA-DR1
Summary for 4FQX
Entry DOI | 10.2210/pdb4fqx/pdb |
Descriptor | HLA class II histocompatibility antigen, DM alpha chain, HLA class II histocompatibility antigen, DM beta chain, Synthetic peptide, ... (7 entities in total) |
Functional Keywords | immune complex, peptide loading, peptide editing, antigen presentation, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 92704.32 |
Authors | Sethi, D.K.,Pos, W.,Wucherpfennig, K.W. (deposition date: 2012-06-25, release date: 2013-01-09, Last modification date: 2020-07-29) |
Primary citation | Pos, W.,Sethi, D.K.,Call, M.J.,Schulze, M.S.,Anders, A.K.,Pyrdol, J.,Wucherpfennig, K.W. Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection. Cell(Cambridge,Mass.), 151:1557-1568, 2012 Cited by PubMed: 23260142DOI: 10.1016/j.cell.2012.11.025 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.599 Å) |
Structure validation
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