PDB: 217686 件ウェブページステータス検索Chemie searchBIRD

---

6EUV	Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound azaindole cap-binding inhibitor (VX-787) 分子名称: (2S,3S)-3-[[5-fluoranyl-2-(5-fluoranyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, NICKEL (II) ION, Polymerase basic protein 2 著者 Cusack, S, Lethier, M. 登録日 2017-10-31 公開日 2017-12-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors. Nucleic Acids Res., 46, 2018
7KGY	Beta-glucuronidase from Faecalibacterium prausnitzii bound to the inhibitor UNC10201652-glucuronide 分子名称: 8-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-5-(morpholin-4-yl)-1,2,3,4-tetrahydro[1,2,3]triazino[4',5':4,5]thieno[2,3 -c]isoquinoline, Beta-glucuronidase, GLYCEROL 著者 Simpson, J.B, Redinbo, M.R. 登録日 2020-10-19 公開日 2021-11-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract. Nat Commun, 13, 2022
5F4H	Archael RuvB-like Holiday junction helicase 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Nucleotide binding protein PINc 著者 Zhai, B, DuPrez, K.T, Doukov, T.I, Shen, Y, Fan, L. 登録日 2015-12-03 公開日 2016-12-21 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (2.699 Å) 主引用文献 Structure and Function of a Novel ATPase that Interacts with Holliday Junction Resolvase Hjc and Promotes Branch Migration. J. Mol. Biol., 429, 2017
7ZJ5	Unbound state of a brocolli-pepper aptamer FRET tile. 分子名称: POTASSIUM ION, brocolli-pepper aptamer 著者 McRae, E.K.S, Vallina, N.S, Hansen, B.K, Boussebayle, A, Andersen, E.S. 登録日 2022-04-08 公開日 2023-04-19 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.55 Å) 主引用文献 Structure determination of Pepper-Broccoli FRET pair by RNA origami scaffolding To Be Published
7FBP	FXIIa-cMCoFx1 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor XIIa light chain, cMCoFx1 著者 Sengoku, T, Liu, W, de Veer, S.J, Huang, Y.H, Okada, C, Zdenek, C.N, Fry, B.G, Swedberg, J.E, Passioura, T, Craik, D.J, Suga, H, Ogata, K. 登録日 2021-07-12 公開日 2021-11-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human beta-Factor XIIa in a Cyclotide Scaffold. J.Am.Chem.Soc., 143, 2021
5L33	Crystal structure of a de novo designed protein with curved beta-sheet 分子名称: denovo NTF2 著者 Oberdorfer, G, Marcos, E, Basanta, B, Chidyausiku, T.M, Sankaran, B, Baker, D. 登録日 2016-08-03 公開日 2017-01-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Principles for designing proteins with cavities formed by curved beta sheets. Science, 355, 2017
8PSN	Tilapia Lake Virus polymerase in vRNA initiation state (transcriptase conformation) 分子名称: 5' vRNA end - vRNA loop (40-mer), DNA (5'-D(*(CTP))-3'), MAGNESIUM ION, ... 著者 Arragain, B, Cusack, S. 登録日 2023-07-13 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.73 Å) 主引用文献 Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023
6UZE	Anthrax toxin protective antigen channels bound to edema factor 分子名称: CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen 著者 Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. 登録日 2019-11-15 公開日 2020-03-04 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors. Nat Commun, 11, 2020
6EYF	Butyrylcolinesterase expressed in CHO cells co-crystallised with a rivastigmine analogue 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cholinesterase, GLYCEROL, ... 著者 Brazzolotto, X, De la Mora, E, Dighe, S, Ross, B. 登録日 2017-11-12 公開日 2018-11-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model Commun Chem, 2019
8PSO	Tilapia Lake Virus polymerase in vRNA initiation state (core only) 分子名称: 5' vRNA end - vRNA loop (40-mer), DNA (5'-D(*(CTP))-3'), MAGNESIUM ION, ... 著者 Arragain, B, Cusack, S. 登録日 2023-07-13 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023
7T58	Crystal structure of Miz1 BTB domain 分子名称: DIMETHYL SULFOXIDE, Zinc finger and BTB domain-containing protein 17 著者 Linhares, B.M, Cierpicki, T. 登録日 2021-12-11 公開日 2022-12-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.05333114 Å) 主引用文献 Prediction of BTB domain ligandability guided by protein dynamics To Be Published
8PT7	Tilapia Lake Virus polymerase in cRNA pre-initiation state mode A (core-endo only) 分子名称: 5'/3' cRNA ends - cRNA loop (40-mer), MAGNESIUM ION, Polymerase acidic protein (PA-like), ... 著者 Arragain, B, Cusack, S. 登録日 2023-07-13 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023
8PSQ	Tilapia Lake Virus polymerase in cRNA pre-initiation state mode A (core only) 分子名称: 5' cRNA end - cRNA loop (40-mer), MAGNESIUM ION, Polymerase acidic protein (PA-like), ... 著者 Arragain, B, Cusack, S. 登録日 2023-07-13 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.65 Å) 主引用文献 Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023
8PSU	Tilapia Lake Virus polymerase in vRNA pre-initiation state mode A (core only) 分子名称: 5' vRNA end - vRNA loop (40-mer), Polymerase acidic protein (PA-like), Putative PB1, ... 著者 Arragain, B, Cusack, S. 登録日 2023-07-13 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023
8PSX	Tilapia Lake Virus polymerase in vRNA elongation state (transcriptase conformation) 分子名称: 5' vRNA end - vRNA loop (40-mer), MAGNESIUM ION, Polymerase acidic protein (PA-like), ... 著者 Arragain, B, Cusack, S. 登録日 2023-07-13 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023
8PT6	Tilapia Lake Virus polymerase in vRNA initiation state (replicase conformation) 分子名称: 5' vRNA end - vRNA loop (40-mer), DNA (5'-D(*(CTP))-3'), MAGNESIUM ION, ... 著者 Arragain, B, Cusack, S. 登録日 2023-07-13 公開日 2023-12-27 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.03 Å) 主引用文献 Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family. Nat Commun, 14, 2023
5L9A	L-threonine dehydrogenase from trypanosoma brucei. 分子名称: ACETATE ION, L-threonine 3-dehydrogenase 著者 Erskine, P.T, Cooper, J.B, Adjogatse, E, Kelly, J, Wood, S.P. 登録日 2016-06-09 公開日 2016-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. Acta Crystallogr D Struct Biol, 74, 2018
8PJN	Catalytic module of human CTLH E3 ligase bound to multiphosphorylated UBE2H~ubiquitin 分子名称: E3 ubiquitin-protein transferase MAEA, E3 ubiquitin-protein transferase RMND5A, Ubiquitin, ... 著者 Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A. 登録日 2023-06-23 公開日 2024-01-03 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies. Mol.Cell, 84, 2024
3IHK	Crystal Structure of thiamin pyrophosphokinase from S.mutans, Northeast Structural Genomics Consortium Target SmR83 分子名称: MAGNESIUM ION, PHOSPHATE ION, THIAMINE DIPHOSPHATE, ... 著者 Kuzin, A, Abashidze, M, Seetharaman, J, Vorobiev, S, Mao, M, Xiao, R, Ciccosanti, C, Maglaqui, M, Foote, E.L, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2009-07-30 公開日 2009-08-25 最終更新日 2019-07-24 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Northeast Structural Genomics Consortium Target SmR83 To be published
5TVR	JMJD2A in complex with Ni(II) and alpha-Ketoglutarate 分子名称: 2-OXOGLUTARIC ACID, Lysine-specific demethylase 4A, NICKEL (II) ION, ... 著者 Cascella, B, Lee, S.G, Jez, J.M. 登録日 2016-11-09 公開日 2017-02-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.093 Å) 主引用文献 The small molecule JIB-04 disrupts O2 binding in the Fe-dependent histone demethylase KDM4A/JMJD2A. Chem. Commun. (Camb.), 53, 2017
5F4M	Protruding domain of GII.17 norovirus Kawasaki323 分子名称: 1,2-ETHANEDIOL, Capsid protein 著者 Singh, B.K, Hansman, G.S. 登録日 2015-12-03 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structural Evolution of the Emerging 2014-2015 GII.17 Noroviruses. J.Virol., 90, 2015
8PMQ	Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin 分子名称: E3 ubiquitin-protein ligase RMD5, Protein FYV10, Ubiquitin, ... 著者 Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A. 登録日 2023-06-29 公開日 2024-01-03 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.53 Å) 主引用文献 Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies. Mol.Cell, 84, 2024
5L16	Crystal Structure of N-terminus truncated selenophosphate synthetase from Leishmania major 分子名称: Putative selenophosphate synthetase, SULFATE ION 著者 Faim, L.M, Silva, I.R, Pereira, H.M, Dias, M.B, Silva, M.T.A, Brandao-Neto, J, Thiemann, O.H. 登録日 2016-07-28 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.882 Å) 主引用文献 Trypanosomatid selenophosphate synthetase structure, function and interaction with selenocysteine lyase. Plos Negl Trop Dis, 14, 2020
4XFU	Structure of IL-18 SER Mutant V 分子名称: Interleukin-18 著者 Krumm, B.E, Meng, X, Xiang, Y, Deng, J. 登録日 2014-12-29 公開日 2015-06-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Crystallization of interleukin-18 for structure-based inhibitor design. Acta Crystallogr.,Sect.F, 71, 2015
4XGT	Structure of RNA Helicase FRH a Critical Component of the Neurospora Crassa Circadian Clock 分子名称: FRQ-interacting RNA helicase 著者 Conrad, K.S, Crane, B.C. 登録日 2015-01-02 公開日 2016-07-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Structure of the frequency-interacting RNA helicase: a protein interaction hub for the circadian clock. Embo J., 35, 2016

<642643644645646647648649650651652653654655656657>