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3RTY
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Structure of an Enclosed Dimer Formed by The Drosophila Period Protein
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Period circadian protein
著者King, H.A, Hoelz, A, Crane, B.R, Young, M.W.
登録日2011-05-04
公開日2011-12-21
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of an enclosed dimer formed by the Drosophila period protein.
J.Mol.Biol., 413, 2011
3F8Z
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Human Dihydrofolate Reductase Structural Data with Active Site Mutant Enzyme Complexes
分子名称: 2,4-DIAMINO-5-[2-METHOXY-5-(4-CARBOXYBUTYLOXY)BENZYL]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Cody, V, Pace, J, Makin, J, Piraino, J, Queener, S.F, Rosowsky, A.
登録日2008-11-13
公開日2009-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Correlations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes.
Biochemistry, 48, 2009
3F91
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Structural Data for Human Active Site Mutant Enzyme Complexes
分子名称: 2,4-DIAMINO-5-[2-METHOXY-5-(4-CARBOXYBUTYLOXY)BENZYL]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Cody, V, Pace, J, Makin, J, Piraino, J, Queener, S.F, Rosowsky, A.
登録日2008-11-13
公開日2009-08-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Correlations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes.
Biochemistry, 48, 2009
5H6R
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BU of 5h6r by Molmil
Crystal structure of LSD1-CoREST in complex with peptide 13
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ...
著者Kkuchi, M, Amano, Y, Sato, S, Yokoyama, S, Umezawa, N, Higuchi, T, Umehara, T.
登録日2016-11-14
公開日2017-04-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1.
Bioorg. Med. Chem., 25, 2017
1PD7
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BU of 1pd7 by Molmil
Extended SID of Mad1 bound to the PAH2 domain of mSin3B
分子名称: Mad1, Sin3b protein
著者Van Ingen, H, Lasonder, E, Jansen, J.F, Kaan, A.M, Spronk, C.A, Stunnenberg, H.G, Vuister, G.W.
登録日2003-05-19
公開日2004-01-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Extension of the binding motif of the sin3 interacting domain of the mad family proteins(,).
Biochemistry, 43, 2004
6WC6
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BU of 6wc6 by Molmil
Crystal structure of a truncated LSD1:CoREST in the presence of an LSD1-NT peptide
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LSD1-NT peptide, Lysine-specific histone demethylase 1A, ...
著者Reiter, N.J, Zeng, D, Senanayaka, D.
登録日2020-03-29
公開日2021-06-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Identification of structure and nucleosome binding within the N-terminus of lysine specific demethylase 1
To Be Published
5BQT
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BU of 5bqt by Molmil
Structure of TrmBL2, an archaeal chromatin protein, shows a novel mode of DNA binding.
分子名称: CALCIUM ION, Putative HTH-type transcriptional regulator TrmBL2
著者Ahmad, M.U, Diederichs, K, Welte, W.
登録日2015-05-29
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Insights into Nonspecific Binding of DNA by TrmBL2, an Archaeal Chromatin Protein.
J.Mol.Biol., 427, 2015
5BOX
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BU of 5box by Molmil
Structure of TrmBL2, an archaeal chromatin protein, shows a novel mode of DNA binding.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (25-MER), DNA TGM (25-MER), ...
著者Ahmad, M.U, Diederichs, K, Welte, W.
登録日2015-05-27
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Insights into Nonspecific Binding of DNA by TrmBL2, an Archaeal Chromatin Protein.
J.Mol.Biol., 427, 2015
1ZHO
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BU of 1zho by Molmil
The structure of a ribosomal protein L1 in complex with mRNA
分子名称: 50S ribosomal protein L1, POTASSIUM ION, mRNA
著者Nevskaya, N, Tishchenko, S, Volchkov, S, Kljashtorny, V, Nikonova, E, Nikonov, O, Nikulin, A, Kohrer, C, Piendl, W, Zimmermann, R, Stockley, P, Garber, M, Nikonov, S.
登録日2005-04-26
公開日2006-05-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献New insights into the interaction of ribosomal protein L1 with RNA.
J.Mol.Biol., 355, 2006
5BPI
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BU of 5bpi by Molmil
Structure of TrmBL2, an archaeal chromatin protein, shows a novel mode of DNA binding.
分子名称: DNA (5'-D(P*TP*AP*TP*AP*TP*CP*AP*CP*TP*AP*TP*CP*GP*AP*TP*GP*AP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*AP*TP*AP*TP*CP*AP*TP*CP*GP*AP*TP*AP*GP*TP*GP*AP*TP*AP*TP*A)-3'), GLYCEROL, ...
著者Ahmad, M.U, Diederichs, K, Welte, W.
登録日2015-05-28
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.198 Å)
主引用文献Structural Insights into Nonspecific Binding of DNA by TrmBL2, an Archaeal Chromatin Protein.
J.Mol.Biol., 427, 2015
3GA1
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BU of 3ga1 by Molmil
Crystal Structure of the Human Nac1 POZ Domain
分子名称: NITRATE ION, Nucleus accumbens-associated protein 1
著者Stead, M.A, Carr, S.B, Wright, S.C.
登録日2009-02-16
公開日2009-05-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the human Nac1 POZ domain
Acta Crystallogr.,Sect.F, 65, 2009
3FS6
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BU of 3fs6 by Molmil
Correlations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes
分子名称: 2,4-DIAMINO-5-[2-METHOXY-5-(4-CARBOXYBUTYLOXY)BENZYL]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Cody, V, Pace, J, Makin, J, Piraino, J, Queener, S.F, Rosowsky, A.
登録日2009-01-09
公開日2009-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Correlations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes.
Biochemistry, 48, 2009
3GLB
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BU of 3glb by Molmil
Crystal structure of the effector binding domain of a CATM variant (R156H)
分子名称: (2Z,4Z)-HEXA-2,4-DIENEDIOIC ACID, GLYCEROL, HTH-type transcriptional regulator catM, ...
著者Ezezika, O.C, Craven, S.H, Neidle, E.L, Momany, C.
登録日2009-03-11
公開日2009-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Inducer responses of BenM, a LysR-type transcriptional regulator from Acinetobacter baylyi ADP1.
Mol.Microbiol., 72, 2009
3F8Y
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BU of 3f8y by Molmil
Correlations of Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes
分子名称: 2,4-DIAMINO-5-[2-METHOXY-5-(4-CARBOXYBUTYLOXY)BENZYL]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Cody, V, Pace, J, Makin, J, Piraino, J, Queener, S.F, Rosowsky, A.
登録日2008-11-13
公開日2009-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Correlations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes.
Biochemistry, 48, 2009
8HY0
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BU of 8hy0 by Molmil
Composite cryo-EM structure of the histone deacetylase complex Rpd3S in complex with nucleosome
分子名称: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ...
著者Cui, H, Wang, H.
登録日2023-01-05
公開日2023-09-27
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
8HXY
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BU of 8hxy by Molmil
Cryo-EM structure of the histone deacetylase complex Rpd3S in complex with nucleosome
分子名称: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ...
著者Cui, H, Wang, H.
登録日2023-01-05
公開日2023-09-27
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
7SQB
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BU of 7sqb by Molmil
PPAR gamma LBD bound to Inverse Agonist SR10221
分子名称: (2S)-2-{5-[(5-{[(1S)-1-(4-tert-butylphenyl)ethyl]carbamoyl}-2,3-dimethyl-1H-indol-1-yl)methyl]-2-chlorophenoxy}propanoic acid, Peroxisome proliferator-activated receptor gamma
著者Frkic, R.L, Pederick, J.L, Bruning, J.B.
登録日2021-11-05
公開日2023-05-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献PPAR gamma Corepression Involves Alternate Ligand Conformation and Inflation of H12 Ensembles.
Acs Chem.Biol., 18, 2023
6ZVH
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BU of 6zvh by Molmil
EDF1-ribosome complex
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Best, K.M, Denk, T, Cheng, J, Thoms, M, Berninghausen, O, Beckmann, R.
登録日2020-07-24
公開日2020-08-19
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献EDF1 coordinates cellular responses to ribosome collisions.
Elife, 9, 2020
4DOS
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BU of 4dos by Molmil
Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, Bound to DLPC and a Fragment of TIF-2
分子名称: DIUNDECYL PHOSPHATIDYL CHOLINE, Nuclear receptor coactivator 2, Nuclear receptor subfamily 5 group A member 2, ...
著者Musille, P.M, Ortlund, E.A.
登録日2012-02-10
公開日2012-04-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation.
Nat.Struct.Mol.Biol., 19, 2012
6W1E
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BU of 6w1e by Molmil
Crystal structure of Streptococcus thermophilus SHP pheromone receptor Rgg3
分子名称: Positive transcriptional regulator MutR family, SULFATE ION
著者Neiditch, M.B, Capodagli, G.C.
登録日2020-03-04
公開日2020-10-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献Structure-function studies of Rgg binding to pheromones and target promoters reveal a model of transcription factor interplay.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W1F
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BU of 6w1f by Molmil
Crystal structure of Streptococcus thermophilus SHP pheromone receptor Rgg3 bound to DNA
分子名称: DNA (30-MER), Positive transcriptional regulator MutR family
著者Neiditch, M.B, Capodagli, G.C.
登録日2020-03-04
公開日2020-10-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure-function studies of Rgg binding to pheromones and target promoters reveal a model of transcription factor interplay.
Proc.Natl.Acad.Sci.USA, 117, 2020
4J2L
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BU of 4j2l by Molmil
Crystal Structure of AXH domain complexed with Capicua
分子名称: Ataxin-1, Protein capicua homolog
著者Song, J.-J, Kim, E.
登録日2013-02-04
公開日2013-04-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural basis of protein complex formation and reconfiguration by polyglutamine disease protein Ataxin-1 and Capicua
Genes Dev., 27, 2013
4G9Y
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BU of 4g9y by Molmil
Crystal Structure of the PcaV transcriptional regulator from Streptomyces coelicolor
分子名称: GLYCEROL, PcaV transcriptional regulator
著者Brown, B.L, Davis, J.R, Sello, J.K, Page, R.
登録日2012-07-24
公開日2013-06-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.051 Å)
主引用文献Study of PcaV from Streptomyces coelicolor yields new insights into ligand-responsive MarR family transcription factors.
Nucleic Acids Res., 41, 2013
4FHT
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BU of 4fht by Molmil
Crystal Structure of the PcaV transcriptional regulator from Streptomyces coelicolor in complex with its natural ligand
分子名称: 3,4-DIHYDROXYBENZOIC ACID, ACETATE ION, PcaV transcriptional regulator
著者Brown, B.L, Davis, J.R, Sello, J.K, Page, R.
登録日2012-06-06
公開日2013-04-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Study of PcaV from Streptomyces coelicolor yields new insights into ligand-responsive MarR family transcription factors.
Nucleic Acids Res., 41, 2013
7XVA
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Crystal structure of the Human TR4 Ligand Binding Domain in complex with the JAZF1 corepressor fragment
分子名称: Juxtaposed with another zinc finger protein 1, Nuclear receptor subfamily 2 group C member 2
著者Liu, Y, Chen, Z.
登録日2022-05-21
公開日2022-12-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.856 Å)
主引用文献Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation.
Nucleic Acids Res., 51, 2023

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