7XVA

Crystal structure of the Human TR4 Ligand Binding Domain in complex with the JAZF1 corepressor fragment

Summary for 7XVA

• Entry DOI: 10.2210/pdb7xva/pdb
• Descriptor: Nuclear receptor subfamily 2 group C member 2, Juxtaposed with another zinc finger protein 1 (3 entities in total)
• Functional Keywords: nuclear receptor, corepressor, transcriptional regulation, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 31891.46

Authors

Liu, Y.,Chen, Z. (deposition date: 2022-05-21, release date: 2022-12-28, Last modification date: 2023-11-29)

• Primary citation: Liu, Y.,Ma, L.,Li, M.,Tian, Z.,Yang, M.,Wu, X.,Wang, X.,Shang, G.,Xie, M.,Chen, Y.,Liu, X.,Jiang, L.,Wu, W.,Xu, C.,Xia, L.,Li, G.,Dai, S.,Chen, Z.; Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation.; Nucleic Acids Res., 51:1443-1457, 2023; PubMed: 36651297; DOI: 10.1093/nar/gkac1259

Experimental method

X-RAY DIFFRACTION (1.856 Å)