8TZ4
 
 | | Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, subset reconstruction | | 分子名称: | (2~{R},3~{R},4~{S},5~{R})-2-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolane-2-carbonitrile, Sodium/nucleoside cotransporter | | 著者 | Wright, N.J, Lee, S.-Y. | | 登録日 | 2023-08-26 | | 公開日 | 2024-03-13 | | 最終更新日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 20, 2024
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8TZ2
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8TZ1
 | | Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Ribavirin | | 分子名称: | 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, ... | | 著者 | Wright, N.J, Lee, S.-Y. | | 登録日 | 2023-08-26 | | 公開日 | 2024-03-13 | | 最終更新日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | | 主引用文献 | Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 20, 2024
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8TZ7
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8TZ5
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8TZ6
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8TZA
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8TZ9
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8TZ3
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8TZ8
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4OXF
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8TZD
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4OXB
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1HLW
 | | STRUCTURE OF THE H122A MUTANT OF THE NUCLEOSIDE DIPHOSPHATE KINASE | | 分子名称: | NUCLEOSIDE DIPHOSPHATE KINASE | | 著者 | Admiraal, S.J, Meyer, P, Schneider, B, Deville-Bonne, D, Janin, J, Herschlag, D. | | 登録日 | 2000-12-04 | | 公開日 | 2001-02-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Chemical rescue of phosphoryl transfer in a cavity mutant: a cautionary tale for site-directed mutagenesis.
Biochemistry, 40, 2001
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1HDK
 | | Charcot-Leyden Crystal Protein - pCMBS Complex | | 分子名称: | EOSINOPHIL LYSOPHOSPHOLIPASE, PARA-MERCURY-BENZENESULFONIC ACID | | 著者 | Ackerman, S.J, Savage, M.P, Liu, L, Leonidas, D.D, Kwatia, M.A, Swaminathan, G.J, Acharya, K.R. | | 登録日 | 2000-11-16 | | 公開日 | 2001-11-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Charcot-Leyden Crystal Protein (Galectin-10) is not a Dual Function Galectin with Lysophospholipase Activity But Binds a Lysophospholipase Inhibitor in a Novel Structural Fashion.
J.Biol.Chem., 277, 2002
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3B6F
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3B6G
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3THG
 | | Crystal structure of the creosote Rubisco activase C-domain | | 分子名称: | GLYCEROL, Ribulose bisphosphate carboxylase/oxygenase activase 1, chloroplastic | | 著者 | Henderson, J.N, Kuriata, A.M, Fromme, R, Salvucci, M.E, Wachter, R.M. | | 登録日 | 2011-08-18 | | 公開日 | 2011-08-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Atomic resolution x-ray structure of the substrate recognition domain of higher plant ribulose-bisphosphate carboxylase/oxygenase (Rubisco) activase.
J.Biol.Chem., 286, 2011
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3BBC
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6IKA
 | | HIV-1 reverse transcriptase with Q151M/G112S/D113A/Y115F/F116Y/F160L/I159L:DNA:entecavir-triphosphate ternary complex | | 分子名称: | DNA/RNA (38-MER), GLYCEROL, HIV-1 RT p51 subunit, ... | | 著者 | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | | 登録日 | 2018-10-15 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.598 Å) | | 主引用文献 | Active-site deformation in the structure of HIV-1 RT with HBV-associated septuple amino acid substitutions rationalizes the differential susceptibility of HIV-1 and HBV against 4'-modified nucleoside RT inhibitors.
Biochem. Biophys. Res. Commun., 509, 2019
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6IK9
 | | HIV-1 reverse transcriptase with Q151M/G112S/D113A/Y115F/F116Y/F160L/I159L:DNA:dGTP ternary complex | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... | | 著者 | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | | 登録日 | 2018-10-15 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.435 Å) | | 主引用文献 | Active-site deformation in the structure of HIV-1 RT with HBV-associated septuple amino acid substitutions rationalizes the differential susceptibility of HIV-1 and HBV against 4'-modified nucleoside RT inhibitors.
Biochem. Biophys. Res. Commun., 509, 2019
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6R4T
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6R5E
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6RB4
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6R5D
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