6RB4
Crystal structure of the Pri1 subunit of human primase
Summary for 6RB4
| Entry DOI | 10.2210/pdb6rb4/pdb |
| Related | 6R4S 6R4T 6R4U 6R5D 6R5E |
| Descriptor | DNA primase small subunit, 1,2-ETHANEDIOL, ZINC ION, ... (4 entities in total) |
| Functional Keywords | primase, dna-dependent rna polymerase, atp, priming, replication |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 49034.20 |
| Authors | Kilkenny, M.L.,Pellegrini, L. (deposition date: 2019-04-09, release date: 2019-09-11, Last modification date: 2024-01-24) |
| Primary citation | Holzer, S.,Rzechorzek, N.J.,Short, I.R.,Jenkyn-Bedford, M.,Pellegrini, L.,Kilkenny, M.L. Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine. Acs Chem.Biol., 14:1904-1912, 2019 Cited by PubMed: 31479243DOI: 10.1021/acschembio.9b00367 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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