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6R5D

Crystal structure of the Pri1 subunit of human primase bound to dATP

Summary for 6R5D
Entry DOI10.2210/pdb6r5d/pdb
Related6R4S 6R4T 6R4U 6R5E 6RB4
DescriptorDNA primase small subunit, ZINC ION, MANGANESE (II) ION, ... (6 entities in total)
Functional Keywordsprimase, dna-dependent rna polymerase, atp, priming, replication
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight99456.71
Authors
Kilkenny, M.L.,Pellegrini, L. (deposition date: 2019-03-24, release date: 2019-09-11, Last modification date: 2024-01-24)
Primary citationHolzer, S.,Rzechorzek, N.J.,Short, I.R.,Jenkyn-Bedford, M.,Pellegrini, L.,Kilkenny, M.L.
Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14:1904-1912, 2019
Cited by
PubMed: 31479243
DOI: 10.1021/acschembio.9b00367
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

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