Nucleosome core particle treated with cisplatin

Summary for 3B6F

Related1KX5 3B6G
Descriptor147-MER DNA, Histone H3.2, Histone H4, ... (7 entities in total)
Functional Keywordsnucleosome, chromatin, platinum adduct, cisplatin, anti-cancer, drug, acetylation, chromosomal protein, dna-binding, methylation, nucleosome core, nucleus, phosphorylation, ubl conjugation, structural protein-dna complex, structural protein/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus P84233 P62799 P02281
Nucleus (By similarity) Q6AZJ8
Total number of polymer chains10
Total molecular weight199426.87
Wu, B.,Davey, C.A. (deposition date: 2007-10-29, release date: 2007-12-25, Last modification date: 2011-07-13)
Primary citation
Wu, B.,Droge, P.,Davey, C.A.
Site selectivity of platinum anticancer therapeutics
Nat.Chem.Biol., 4:110-112, 2008
PubMed: 18157123 (PDB entries with the same primary citation)
DOI: 10.1038/nchembio.2007.58
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.373195.6%9.5%10.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution