PDB: 31311 件ウェブページステータス検索Chemie searchBIRD

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7PPX	ATAD2 in complex with FragLite3 分子名称: 1,2-ETHANEDIOL, 4-bromanyl-1,2-oxazole, ATPase family AAA domain-containing protein 2, ... 著者 Turberville, S, Martin, M.P, Hope, I, Wood, D.J, Ng, Y.M, Heath, R, Endicott, J.A, Noble, M.E.M. 登録日 2021-09-15 公開日 2022-09-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions. J.Med.Chem., 65, 2022
8PFE	Crystal Structure of an Hexavariant of the b1 Domain of Human Neuropilin-1 in Complex with the KDKPPR Peptide 分子名称: ACETATE ION, LYS-ASP-LYS-PRO-PRO-ARG, Neuropilin-1 著者 Jelsch, C, Favier, F, Didierjean, C. 登録日 2023-06-15 公開日 2023-08-02 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 New Crystal Form of Human Neuropilin-1 b1 Fragment with Six Electrostatic Mutations Complexed with KDKPPR Peptide Ligand. Molecules, 28, 2023
6N0Y	Crystal structure of Anaerolinea thermophila mevalonate 5-phosphate decarboxylase complexed with (R)-MVAPP 分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, Diphosphomevalonate decarboxylase 著者 Noel, J.P, Thomas, S.T, Louie, G.V. 登録日 2018-11-07 公開日 2019-07-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase. Acs Chem.Biol., 14, 2019
7YPP	Structural basis of a superoxide dismutase from a tardigrade, Ramazzottius varieornatus strain YOKOZUNA-1. 分子名称: CALCIUM ION, COPPER (II) ION, Superoxide dismutase [Cu-Zn], ... 著者 Sim, K.-S, Fukuda, Y, Inoue, T. 登録日 2022-08-04 公開日 2023-07-26 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of a superoxide dismutase from a tardigrade: Ramazzottius varieornatus strain YOKOZUNA-1. Acta Crystallogr.,Sect.F, 79, 2023
8T3P	Crystal structure of MonC1 (a flavin-dependent monooxygenase) 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, MonCI 著者 Wang, Q, Mathews, I.I, Kim, C.Y. 登録日 2023-06-07 公開日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Triepoxide formation by a flavin-dependent monooxygenase in monensin biosynthesis. Nat Commun, 14, 2023
5UQ0	FGFR1 kinase domain complex with fragment 2,2-dimethyl-2,3-dihydrobenzofuran-7-carboxamide 分子名称: 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-carboxamide, Fibroblast growth factor receptor 1 著者 Paik, W.-K, Squire, C.J. 登録日 2017-02-05 公開日 2017-02-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Fragment screening diverse active sites To Be Published
7YW2	Crystal structure of tRNA 2'-phosphotransferase from Mus musculus 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, GLYCINE, ... 著者 Yang, X.Y, Liu, X.H. 登録日 2022-08-21 公開日 2023-07-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation. Nucleic Acids Res., 51, 2023
8SX1	PARP4 catalytic domain 分子名称: Protein mono-ADP-ribosyltransferase PARP4 著者 Frigon, L, Pascal, J.M. 登録日 2023-05-19 公開日 2023-11-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structural and biochemical analysis of the PARP1-homology region of PARP4/vault PARP. Nucleic Acids Res., 51, 2023
8SX2	PARP4 catalytic domain bound to EB47 分子名称: 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide, Protein mono-ADP-ribosyltransferase PARP4 著者 Frigon, L, Pascal, J.M. 登録日 2023-05-19 公開日 2023-11-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structural and biochemical analysis of the PARP1-homology region of PARP4/vault PARP. Nucleic Acids Res., 51, 2023
8PUN	Old Yellow Enzyme from the thermophilic Ferrovum sp. JA12 分子名称: 1,2-ETHANEDIOL, 2-ethyl-2-(hydroxymethyl)propane-1,3-diol, CHLORIDE ION, ... 著者 Polidori, N, Gruber, K. 登録日 2023-07-17 公開日 2023-08-02 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Old Yellow Enzyme from the thermophilic Ferrovum sp. JA12 To Be Published
5HVQ	Alternative model of the MAGE-G1 NSE-1 complex 分子名称: Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, ZINC ION 著者 Newman, J.A, Cooper, C.D.O, Roos, A.K, Aitkenhead, H, Oppermann, U.C.T, Cho, H.J, Osman, R, Gileadi, O. 登録日 2016-01-28 公開日 2016-10-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.923 Å) 主引用文献 Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding. Plos One, 11, 2016
7ZC9	Human Pikachurin/EGFLAM C-terminal Laminin-G domain (LG3) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Pikachurin, SULFATE ION 著者 Pantalone, S, Forneris, F. 登録日 2022-03-26 公開日 2023-07-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179. Sci.Signal., 16, 2023
7PSF	Crystal Structure of a Class D Carbapenemase Complexed with Imipenem 分子名称: 1-BUTANOL, BROMIDE ION, Beta-lactamase, ... 著者 Zhou, Q, He, Y, Jin, Y. 登録日 2021-09-23 公開日 2022-10-05 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity Acs Cent.Sci., 2023
8VEX	Crystal structure of PRMT5:MEP50 in complex with MTA and oxamide compound 28 分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, CHLORIDE ION, GLYCEROL, ... 著者 Whittington, D.A. 登録日 2023-12-20 公開日 2024-04-24 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP -Deleted Cancers. J.Med.Chem., 67, 2024
7ZCB	Human Pikachurin/EGFLAM N-terminal Fibronectin-III (1-2) domains 分子名称: CHLORIDE ION, Pikachurin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Pantalone, S, Savino, S, Viti, L.V, Forneris, F. 登録日 2022-03-26 公開日 2023-07-19 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179. Sci.Signal., 16, 2023
7YKC	crystal structure of the Phenylalanine-regulated 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (ARO3) from Saccharomyces cerevisiae 分子名称: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase 著者 Liu, H, Luo, Y. 登録日 2022-07-22 公開日 2023-07-26 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Mechanistic investigation of a D to N mutation in DAHP synthase that dictates carbon flux into the shikimate pathway in yeast. Commun Chem, 6, 2023
7PRK	Factor XII Fibronectin type II (FXII FnII) domain 分子名称: Coagulation factor XII, FORMIC ACID, ZINC ION 著者 Kaira, B.G, Emsley, J. 登録日 2021-09-21 公開日 2022-10-05 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Factor XII Fibronectin type II (FXII FnII) domain To Be Published
7NFG	A hexameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L14A. 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, CC-Type2-(LaId)4-L14A 著者 Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. 登録日 2021-02-07 公開日 2022-03-02 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
8PPZ	Co-crystal structure of FKBP12, compound 7 and the FRB fragment of mTOR 分子名称: (1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-[(~{E})-2-(2-chlorophenyl)ethenyl]-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one, ACETATE ION, CALCIUM ION, ... 著者 Meyners, C, Deutscher, R.C.E, Hausch, F. 登録日 2023-07-10 公開日 2023-08-09 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Co-crystal structure of FKBP12, compound 7 and the FRB fragment of mTOR Chemrxiv, 2023
7NFH	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(MaId)4. 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CC-Type2-(MaId)4 著者 Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. 登録日 2021-02-07 公開日 2022-03-02 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
6N4Y	Metabotropic Glutamate Receptor 5 Extracellular Domain with Nb43 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5, ... 著者 Koehl, A, Hu, H, Feng, D, Sun, B, Chu, M, Weis, W.I, Mathiesen, J.M, Skiniotis, G, Kobilka, B.K. 登録日 2018-11-20 公開日 2019-01-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.262 Å) 主引用文献 Structural insights into the activation of metabotropic glutamate receptors. Nature, 566, 2019
8V9Q	Crystal structure of mGalNAc-T1 in complex with the mucin glycopeptide Muc5AC-13, Mn2+, and UDP. 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Samara, N.L, Collette, A.M. 登録日 2023-12-08 公開日 2024-03-13 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 An unusual dual sugar-binding lectin domain controls the substrate specificity of a mucin-type O-glycosyltransferase. Sci Adv, 10, 2024
8SWY	PARP4 ART domain bound to NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, Protein mono-ADP-ribosyltransferase PARP4 著者 Frigon, L, Pascal, J.M. 登録日 2023-05-19 公開日 2023-11-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural and biochemical analysis of the PARP1-homology region of PARP4/vault PARP. Nucleic Acids Res., 51, 2023
8VCN	GluER mutant - W66F F269Y Q293T F68Y T36E P263L 分子名称: ACETATE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... 著者 Jeffrey, P.D, Sorigue, D.R, Liu, Y, Hyster, T.K. 登録日 2023-12-14 公開日 2024-03-13 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Asymmetric Synthesis of alpha-Chloroamides via Photoenzymatic Hydroalkylation of Olefins. J.Am.Chem.Soc., 146, 2024
8VRS	Mucin 16 peptide fused to MBP in complex with 4H11-scFv antibody 分子名称: 4H11 scFv chain, Maltose/maltodextrin-binding periplasmic protein,Mucin-16 著者 Lee, K, Perry, K, Yeku, O.O, Spriggs, D.R. 登録日 2024-01-22 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Structural basis for antibody recognition of the proximal MUC16 ectodomain. J Ovarian Res, 17, 2024

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