8SX2

PARP4 catalytic domain bound to EB47

Summary for 8SX2

Entry DOI	10.2210/pdb8sx2/pdb
Descriptor	Protein mono-ADP-ribosyltransferase PARP4, 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide (3 entities in total)
Functional Keywords	parp family, adp-ribosyltransferase, marylation, vault, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	75594.77
Authors	Frigon, L.,Pascal, J.M. (deposition date: 2023-05-19, release date: 2023-11-08, Last modification date: 2023-12-20)
Primary citation	Frigon, L.,Pascal, J.M. Structural and biochemical analysis of the PARP1-homology region of PARP4/vault PARP. Nucleic Acids Res., 51:12492-12507, 2023 Cited by PubMed: 37971310 DOI: 10.1093/nar/gkad1064 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation