6BHT
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![BU of 6bht by Molmil](/molmil-images/mine/6bht) | HIV-1 CA hexamer in complex with IP6, orthorhombic crystal form | 分子名称: | Capsid protein p24, INOSITOL HEXAKISPHOSPHATE | 著者 | Zadrozny, K, Wagner, J.M, Ganser-Pornillos, B.K, Pornillos, O. | 登録日 | 2017-10-31 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.689 Å) | 主引用文献 | Inositol phosphates are assembly co-factors for HIV-1. Nature, 560, 2018
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5CL4
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4RU4
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![BU of 4ru4 by Molmil](/molmil-images/mine/4ru4) | Crystal structure of the tailspike protein gp49 from Pseudomonas phage LKA1 | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, SODIUM ION, ... | 著者 | Browning, C, Shneider, M.M, Leiman, P.G. | 登録日 | 2014-11-18 | 公開日 | 2015-11-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.903 Å) | 主引用文献 | The O-specific polysaccharide lyase from the phage LKA1 tailspike reduces Pseudomonas virulence. Sci Rep, 7, 2017
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6G8N
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![BU of 6g8n by Molmil](/molmil-images/mine/6g8n) | Yeast 20S proteasome in complex with Cystargolide B Derivative 2 | 分子名称: | (2~{S},3~{S})-3-methyl-2-[(1~{R})-2-[[(2~{S})-3-methyl-1-[[(2~{S})-3-methyl-1-oxidanylidene-1-phenylmethoxy-butan-2-yl] amino]-1-oxidanylidene-butan-2-yl]amino]-1-oxidanyl-2-oxidanylidene-ethyl]pentanoic acid, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Groll, M, Tello-Aburto, R. | 登録日 | 2018-04-09 | 公開日 | 2018-09-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Design, synthesis, and evaluation of cystargolide-based beta-lactones as potent proteasome inhibitors. Eur J Med Chem, 157, 2018
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6PWP
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![BU of 6pwp by Molmil](/molmil-images/mine/6pwp) | MscS Nanodisc | 分子名称: | Small-conductance mechanosensitive channel | 著者 | Reddy, B.G, Perozo, E. | 登録日 | 2019-07-23 | 公開日 | 2020-01-08 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Molecular basis of force-from-lipids gating in the mechanosensitive channel MscS. Elife, 8, 2019
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8J5V
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5ETW
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![BU of 5etw by Molmil](/molmil-images/mine/5etw) | Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with NLG919 analogue | 分子名称: | (1~{R})-1-cyclohexyl-2-pyrido[3,4-b]indol-9-yl-ethanol, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Wu, S.Y, Peng, Y.H, Wu, J.S. | 登録日 | 2015-11-18 | 公開日 | 2016-02-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Important Hydrogen Bond Networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Design Revealed by Crystal Structures of Imidazoleisoindole Derivatives with IDO1. J.Med.Chem., 59, 2016
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7LUC
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![BU of 7luc by Molmil](/molmil-images/mine/7luc) | Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B | 分子名称: | 01.4B Fab Heavy chain, 01.4B Fab Light chain, 32.4K Fab Heavy chain, ... | 著者 | Wrapp, D, McLellan, J.S. | 登録日 | 2021-02-22 | 公開日 | 2021-04-21 | 最終更新日 | 2021-04-28 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity, 54, 2021
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5IPL
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![BU of 5ipl by Molmil](/molmil-images/mine/5ipl) | SigmaS-transcription initiation complex with 4-nt nascent RNA | 分子名称: | DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Liu, B, Zuo, Y, Steitz, T.A. | 登録日 | 2016-03-09 | 公開日 | 2016-03-30 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
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8V1L
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8C89
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![BU of 8c89 by Molmil](/molmil-images/mine/8c89) | SARS-CoV-2 spike in complex with the 17T2 neutralizing antibody Fab fragment (local refinement of RBD and Fab) | 分子名称: | 17T2 Fab heavy chain, 17T2 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Modrego, A, Carlero, D, Bueno-Carrasco, M.T, Santiago, C, Carolis, C, Arranz, R, Blanco, J, Magri, G. | 登録日 | 2023-01-19 | 公開日 | 2024-01-10 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (4.41 Å) | 主引用文献 | A monoclonal antibody targeting a large surface of the receptor binding motif shows pan-neutralizing SARS-CoV-2 activity. Nat Commun, 15, 2024
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1C94
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![BU of 1c94 by Molmil](/molmil-images/mine/1c94) | REVERSING THE SEQUENCE OF THE GCN4 LEUCINE ZIPPER DOES NOT AFFECT ITS FOLD. | 分子名称: | RETRO-GCN4 LEUCINE ZIPPER | 著者 | Mittl, P.R.E, Deillon, C.A, Sargent, D, Liu, N, Klauser, S, Thomas, R.M, Gutte, B, Gruetter, M.G. | 登録日 | 1999-07-30 | 公開日 | 2000-03-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | The retro-GCN4 leucine zipper sequence forms a stable three-dimensional structure. Proc.Natl.Acad.Sci.USA, 97, 2000
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5U2J
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5TQA
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7RM9
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![BU of 7rm9 by Molmil](/molmil-images/mine/7rm9) | Human Malate Dehydrogenase I (MDHI) | 分子名称: | MALONATE ION, Malate dehydrogenase, cytoplasmic | 著者 | McCue, W, Finzel, B.C. | 登録日 | 2021-07-27 | 公開日 | 2022-01-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Characterization of the Human Cytosolic Malate Dehydrogenase I. Acs Omega, 7, 2022
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5CLA
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5TRP
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5CLD
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7K98
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![BU of 7k98 by Molmil](/molmil-images/mine/7k98) | Preaminoacylation complex of M. tuberculosis PheRS with cognate precursor tRNA and 5'-O-(N-phenylalanyl)sulfamoyl-adenosine (F-AMS) | 分子名称: | 5'-O-(L-phenylalanylsulfamoyl)adenosine, CHLORIDE ION, GLYCEROL, ... | 著者 | Michalska, K, Chang, C, Jedrzejczak, R, Wower, J, Baragana, B, Forte, B, Gilbert, I.H, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-09-28 | 公開日 | 2021-05-12 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation. Nucleic Acids Res., 49, 2021
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8IXT
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6QF9
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![BU of 6qf9 by Molmil](/molmil-images/mine/6qf9) | Structure of an anti-Mcl1 scFv | 分子名称: | scFv | 著者 | Luptak, J. | 登録日 | 2019-01-09 | 公開日 | 2019-11-06 | 最終更新日 | 2019-11-13 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1. Acta Crystallogr D Struct Biol, 75, 2019
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8IXU
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3I5L
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![BU of 3i5l by Molmil](/molmil-images/mine/3i5l) | Allosteric Modulation of DNA by Small Molecules | 分子名称: | (22R,51R)-22,51-diamino-5,11,17,28,34,40,46,57-octamethyl-2,5,8,11,14,17,20,25,28,31,34,37,40,43,46,49,54,57,60,61,64,6 5-docosaazanonacyclo[54.2.1.1~4,7~.1~10,13~.1~16,19~.1~27,30~.1~33,36~.1~39,42~.1~45,48~]hexahexaconta-1(58),4(66),6,10( 65),12,16(64),18,27(63),29,33(62),35,39(61),41,45(60),47,56(59)-hexadecaene-3,9,15,21,26,32,38,44,50,55-decone, 5'-D(*CP*CP*AP*GP*GP*(C38)P*CP*TP*GP*G)-3', CALCIUM ION | 著者 | Chenoweth, D.M, Dervan, P.B. | 登録日 | 2009-07-05 | 公開日 | 2009-07-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Allosteric modulation of DNA by small molecules Proc.Natl.Acad.Sci.USA, 106, 2009
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6QJP
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![BU of 6qjp by Molmil](/molmil-images/mine/6qjp) | Cryo-EM structure of heparin-induced 2N4R tau jagged filaments | 分子名称: | Microtubule-associated protein tau | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | 登録日 | 2019-01-24 | 公開日 | 2019-02-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases. Elife, 8, 2019
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6E0M
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![BU of 6e0m by Molmil](/molmil-images/mine/6e0m) | Structure of Elizabethkingia meningoseptica CdnE cyclic dinucleotide synthase | 分子名称: | DIPHOSPHATE, cGAS/DncV-like nucleotidyltransferase in E. coli homolog | 著者 | Eaglesham, J.B, Whiteley, A.T, de Oliveira Mann, C.C, Morehouse, B.R, Nieminen, E.A, King, D.S, Lee, A.S.Y, Mekalanos, J.J, Kranzusch, P.J. | 登録日 | 2018-07-06 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Bacterial cGAS-like enzymes synthesize diverse nucleotide signals. Nature, 567, 2019
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