3I5L

Allosteric Modulation of DNA by Small Molecules

Summary for 3I5L

• Entry DOI: 10.2210/pdb3i5l/pdb
• Related: 3I5E
• Descriptor: 5'-D(*CP*CP*AP*GP*GP*(C38)P*CP*TP*GP*G)-3', CALCIUM ION, (22R,51R)-22,51-diamino-5,11,17,28,34,40,46,57-octamethyl-2,5,8,11,14,17,20,25,28,31,34,37,40,43,46,49,54,57,60,61,64,6 5-docosaazanonacyclo[54.2.1.1~4,7~.1~10,13~.1~16,19~.1~27,30~.1~33,36~.1~39,42~.1~45,48~]hexahexaconta-1(58),4(66),6,10( 65),12,16(64),18,27(63),29,33(62),35,39(61),41,45(60),47,56(59)-hexadecaene-3,9,15,21,26,32,38,44,50,55-decone, ... (4 entities in total)
• Functional Keywords: cyclic polyamide, dna binder, minor groove binder, pyim polyamide, dna
• Total number of polymer chains: 2
• Total formula weight: 7725.36

Authors

Chenoweth, D.M.,Dervan, P.B. (deposition date: 2009-07-05, release date: 2009-07-28, Last modification date: 2024-02-21)

• Primary citation: Chenoweth, D.M.,Dervan, P.B.; Allosteric modulation of DNA by small molecules; Proc.Natl.Acad.Sci.USA, 106:13175-13179, 2009; PubMed: 19666554; DOI: 10.1073/pnas.0906532106

Experimental method

X-RAY DIFFRACTION (1.18 Å)