6QF9

Structure of an anti-Mcl1 scFv

Summary for 6QF9

Entry DOI	10.2210/pdb6qf9/pdb
Related	6qb3 6qb9 6qf6
Descriptor	scFv (2 entities in total)
Functional Keywords	mcl1, scfv, apoptosis
Biological source	Homo sapiens
Total number of polymer chains	2
Total formula weight	52857.92
Authors	Luptak, J. (deposition date: 2019-01-09, release date: 2019-11-06, Last modification date: 2019-11-13)
Primary citation	Luptak, J.,Bista, M.,Fisher, D.,Flavell, L.,Gao, N.,Wickson, K.,Kazmirski, S.L.,Howard, T.,Rawlins, P.B.,Hargreaves, D. Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1. Acta Crystallogr D Struct Biol, 75:1003-1014, 2019 Cited by PubMed: 31692474 DOI: 10.1107/S2059798319014116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.43 Å)

Structure validation