6QB3

Apo Mcl1 in a complex with a scFv

Summary for 6QB3

Entry DOI	10.2210/pdb6qb3/pdb
Descriptor	Induced myeloid leukemia cell differentiation protein Mcl-1, scFv55 (3 entities in total)
Functional Keywords	mcl1-scfv complex, apoptosis
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	44656.55
Authors	Kazmirski, S.,Hargreaves, D. (deposition date: 2018-12-20, release date: 2019-11-06, Last modification date: 2019-11-13)
Primary citation	Luptak, J.,Bista, M.,Fisher, D.,Flavell, L.,Gao, N.,Wickson, K.,Kazmirski, S.L.,Howard, T.,Rawlins, P.B.,Hargreaves, D. Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1. Acta Crystallogr D Struct Biol, 75:1003-1014, 2019 Cited by PubMed: 31692474 DOI: 10.1107/S2059798319014116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation