PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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5T3Z	3.5 Angstrom Crystal Structure of a Fully and Natively Glycosylated BG505 SOSIP.664 HIV-1 Env Trimer in Complex with the Broadly Neutralizing Antibodies IOMA and 10-1074 分子名称: 10-1074 Heavy Chain, 10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gristick, H.B, Bjorkman, P.J. 登録日 2016-08-26 公開日 2016-10-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site. Nat.Struct.Mol.Biol., 23, 2016
5T3X	3.9 Angstrom Crystal Structure of a Fully and Natively Glycosylated BG505 SOSIP.664 HIV-1 Env Trimer in Complex with the Broadly Neutralizing Antibodies IOMA and 10-1074. 分子名称: 10-1074 Heavy Chain, 10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gristick, H.B, Bjorkman, P.J. 登録日 2016-08-26 公開日 2016-10-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site. Nat.Struct.Mol.Biol., 23, 2016
4HWE	Crystal structure of ectodomain 3 of the IL-13 receptor alpha1 in complex with a human neutralizing monoclonal antibody fragment 分子名称: Fab heavy chain, Fab light chain, GLYCEROL, ... 著者 Xu, Y. 登録日 2012-11-07 公開日 2013-02-27 最終更新日 2013-07-24 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Crystal structure of ectodomain 3 of the IL-13 receptor alpha1 in complex with a human neutralizing monoclonal antibody fragment Biochem.J., 451, 2013
4HWB	Crystal structure of ectodomain 3 of the IL-13 receptor alpha 1 in complex with a human neutralizing monoclonal antibody fragment 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Fab heavy chain, Fab light chain, ... 著者 Xu, Y. 登録日 2012-11-07 公開日 2013-02-27 最終更新日 2013-07-24 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Crystal structure of ectodomain 3 of the IL-13 receptor alpha 1 in complex with a human neutralizing monoclonal antibody fragment Biochem.J., 451, 2013
8GBX	Crystal structure of PC39-50I, an anti-HIV broadly neutralizing antibody 分子名称: PC39-50I Fab heavy chain, PC39-50I Fab light chain 著者 Murrell, S, Omorodion, O, Wilson, I.A. 登録日 2023-02-28 公開日 2023-06-07 最終更新日 2023-07-12 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
8GBY	Crystal structure of PC39-50E, an anti-HIV broadly neutralizing antibody 分子名称: GLYCEROL, PC39-50E Fab heavy chain, PC39-50E Fab light chain 著者 Murrell, S, Omorodion, O, Wilson, I.A. 登録日 2023-02-28 公開日 2023-06-07 最終更新日 2023-07-12 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
8GBW	Crystal structure of PC39-23D, an anti-HIV broadly neutralizing antibody 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PC39-23D Fab heavy chain, ... 著者 Murrell, S, Omorodion, O, Wilson, I.A. 登録日 2023-02-28 公開日 2023-06-07 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
8GC0	Crystal structure of PC39-50L, an anti-HIV broadly neutralizing antibody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PC39-50L Fab heavy chain, PC39-50L Fab light chain 著者 Murrell, S, Omorodion, O, Wilson, I.A. 登録日 2023-02-28 公開日 2023-06-07 最終更新日 2023-07-12 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
8GBV	Crystal structure of PC39-17A, an anti-HIV broadly neutralizing antibody 分子名称: 1,2-ETHANEDIOL, ACETATE ION, PC39-17A Fab heavy chain, ... 著者 Murrell, S, Omorodion, O, Wilson, I.A. 登録日 2023-02-28 公開日 2023-06-07 最終更新日 2023-07-12 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
8GC1	Crystal structure of the unmutated common ancestor (UCA) of the PC39-1 anti-HIV broadly neutralizing antibody lineage 分子名称: PC39-1 UCA Fab heavy chain, PC39-1 UCA Fab light chain 著者 Murrell, S, Omorodion, O, Wilson, I.A. 登録日 2023-02-28 公開日 2023-06-07 最終更新日 2023-07-12 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
8GBZ	Crystal structure of PC39-55C, an anti-HIV broadly neutralizing antibody 分子名称: DI(HYDROXYETHYL)ETHER, PC39-55C Fab heavy chain, PC39-55C Fab light chain 著者 Murrell, S, Omorodion, O, Wilson, I.A. 登録日 2023-02-28 公開日 2023-06-07 最終更新日 2023-07-12 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
8G4T	Vaccine-elicited human antibody 2C09 in complex with HIV-1 envelope trimer BG505 DS-SOSIP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein BG505 DS-SOSIP gp120, ... 著者 Wang, S, Kwong, P.D. 登録日 2023-02-10 公開日 2023-07-12 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (2.81 Å) 主引用文献 HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide. Cell Rep, 42, 2023
4UOM	Electron Cryo-microscopy of Venezuelan Equine Encephalitis Virus TC- 83 in complex with neutralizing antibody Fab F5 分子名称: FAB FRAGMENT HEAVY CHAIN, FAB FRAGMENT LIGHT CHAIN 著者 Porta, J, Jose, J, Roehrig, J.T, Blair, C.D, Kuhn, R.J, Rossmann, M.G. 登録日 2014-06-05 公開日 2014-10-15 最終更新日 2017-08-23 実験手法 ELECTRON MICROSCOPY (17 Å) 主引用文献 Locking and Blocking the Viral Landscape of an Alphavirus with Neutralizing Antibodies. J.Virol., 88, 2014
8S6E	Monoclonal antibody MenW targeting serogroup W of Neisseria meningitidis 分子名称: MenW.01 Heavy chain, MenW.01 Light chain, SODIUM ION 著者 Pietri, G.P, Bertuzzi, S, Karnicar, K, Unione, L, Lisnic, B, Malic, S, Miklic, K, Novak, M, Calloni, I, Santini, L, Usenik, A, Rosaria Romano, M, Adamo, R, Jonjic, S, Turk, D, Jimenez-Barbero, J, Lenac Rovis, T. 登録日 2024-02-27 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Antigenic determinants driving serogroup-specific antibody response to Neisseria meningitidis C, W, and Y capsular polysaccharides: Insights for rational vaccine design. Carbohydr Polym, 341, 2024
7KMG	LY-CoV555 neutralizing antibody against SARS-CoV-2 分子名称: GLYCEROL, LY-CoV555 Fab heavy chain, LY-CoV555 Fab light chain, ... 著者 Hendle, J, Pustilnik, A, Sauder, J.M, Coleman, K.A, Boyles, J.S, Dickinson, C.D. 登録日 2020-11-02 公開日 2021-01-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates. Sci Transl Med, 13, 2021
6B3D	Crystal structure of anti-HIV antibody PGT128 in complex with a bacterially derived synthetic mimetic of Man9. 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... 著者 Murrell, S, Wilson, I.A. 登録日 2017-09-21 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.271 Å) 主引用文献 Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity. Nat Commun, 8, 2017
7KMH	LY-CoV488 neutralizing antibody against SARS-CoV-2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, LY-CoV488 Fab heavy chain, ... 著者 Hendle, J, Pustilnik, A, Sauder, J.M, Boyles, J.S, Dickinson, C.D, Coleman, K.A. 登録日 2020-11-02 公開日 2021-01-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates. Sci Transl Med, 13, 2021
7KMI	LY-CoV481 neutralizing antibody against SARS-CoV-2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, LY-CoV481 Fab heavy chain, ... 著者 Hendle, J, Pustilnik, A, Sauder, J.M, Coleman, K.A, Boyles, J.S, Dickinson, C.D. 登録日 2020-11-02 公開日 2021-01-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates. Sci Transl Med, 13, 2021
8WSP	Crystal structure of SFTSV Gn and antibody SF5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab5-H, Ab5-L, ... 著者 Chang, Z, Gao, F, Wu, Y. 登録日 2023-10-17 公開日 2024-06-12 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model. Proc.Natl.Acad.Sci.USA, 121, 2024
8WSU	Crystal structure of SFTSV Gc and antibody 分子名称: Ab-H, Ab-L, Glycoprotein C 著者 Chang, Z, Gao, F, Wu, Y. 登録日 2023-10-17 公開日 2024-06-12 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model. Proc.Natl.Acad.Sci.USA, 121, 2024
8WSN	Crystal structure of SFTSV Gn and antibody SF1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab1-H, ... 著者 Chang, Z, Gao, F, Wu, Y. 登録日 2023-10-17 公開日 2024-06-12 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model. Proc.Natl.Acad.Sci.USA, 121, 2024
5YY4	Crystal structure of the scFv antibody 4B08 with sulfated epitope peptide 分子名称: C-C chemokine receptor type 5, CHLORIDE ION, SULFATE ION, ... 著者 Caaveiro, J.M.M, Miyanabe, K, Tsumoto, K. 登録日 2017-12-07 公開日 2018-07-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Tyrosine Sulfation Restricts the Conformational Ensemble of a Flexible Peptide, Strengthening the Binding Affinity for an Antibody Biochemistry, 57, 2018
6BFS	The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies 分子名称: Fab Heavy Chain, Fab light Chain, Granulocyte-macrophage colony-stimulating factor 著者 Dhagat, U, Hercus, T.R, Broughton, S.E, Nero, T.L, Lopez, A.F, Parker, M.W. 登録日 2017-10-26 公開日 2018-09-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities. MAbs, 10, 2018
6BFQ	The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies 分子名称: Fab Heavy chain, Fab Light Chain, Granulocyte-macrophage colony-stimulating factor 著者 Dhagat, U, Hercus, T.R, Broughton, S.E, Nero, T.L, Lopez, A.F, Parker, M.W. 登録日 2017-10-26 公開日 2018-09-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities. MAbs, 10, 2018
7E23	SARS-CoV-2 spike in complex with the CA521 neutralizing antibody Fab (focused refinement on Fab-RBD) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CA521 Heavy Chain, CA521 Light Chain, ... 著者 Liu, C, Song, D, Dou, C. 登録日 2021-02-04 公開日 2021-05-05 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure and function analysis of a potent human neutralizing antibody CA521 FALA against SARS-CoV-2. Commun Biol, 4, 2021

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