7E23

SARS-CoV-2 spike in complex with the CA521 neutralizing antibody Fab (focused refinement on Fab-RBD)

Summary for 7E23

• Entry DOI: 10.2210/pdb7e23/pdb
• EMDB information: 30950
• Descriptor: Spike protein S1, CA521 Heavy Chain, CA521 Light Chain, ... (4 entities in total)
• Functional Keywords: spike, sars-cov-2, antibody, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 3
• Total formula weight: 94468.60

Authors

Liu, C.,Song, D.,Dou, C. (deposition date: 2021-02-04, release date: 2021-05-05)

• Primary citation: Song, D.,Wang, W.,Dong, C.,Ning, Z.,Liu, X.,Liu, C.,Du, G.,Sha, C.,Wang, K.,Lu, J.,Sun, B.,Zhao, Y.,Wang, Q.,Xu, H.,Li, Y.,Shen, Z.,Jiao, J.,Wang, R.,Tian, J.,Liu, W.,Wang, L.,Deng, Y.Q.,Dou, C.; Structure and function analysis of a potent human neutralizing antibody CA521 FALA against SARS-CoV-2.; Commun Biol, 4:500-500, 2021; PubMed: 33893388; DOI: 10.1038/s42003-021-02029-w

Experimental method

ELECTRON MICROSCOPY (3.3 Å)