5YY4

Crystal structure of the scFv antibody 4B08 with sulfated epitope peptide

Summary for 5YY4

Entry DOI	10.2210/pdb5yy4/pdb
Descriptor	scFv 4B08, C-C chemokine receptor type 5, SULFATE ION, ... (5 entities in total)
Functional Keywords	antibody, biomolecular recognition, md simulations, thermodynamics, immune system
Biological source	Mus musculus More
Total number of polymer chains	2
Total formula weight	28394.64
Authors	Caaveiro, J.M.M.,Miyanabe, K.,Tsumoto, K. (deposition date: 2017-12-07, release date: 2018-07-18, Last modification date: 2023-11-22)
Primary citation	Miyanabe, K.,Yamashita, T.,Abe, Y.,Akiba, H.,Takamatsu, Y.,Nakakido, M.,Hamakubo, T.,Ueda, T.,Caaveiro, J.M.M.,Tsumoto, K. Tyrosine Sulfation Restricts the Conformational Ensemble of a Flexible Peptide, Strengthening the Binding Affinity for an Antibody Biochemistry, 57:4177-4185, 2018 Cited by PubMed: 29936828 DOI: 10.1021/acs.biochem.8b00592 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.59 Å)

Structure validation