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7XW8
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BU of 7xw8 by Molmil
Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAK-418 distomer, FAD-adduct
分子名称: GLYCEROL, Lysine-specific histone demethylase 1A, MAGNESIUM ION, ...
著者Oki, H.
登録日2022-05-26
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Design, synthesis, and structure-activity relationship of TAK-418 and its derivatives as a novel series of LSD1 inhibitors with lowered risk of hematological side effects.
Eur.J.Med.Chem., 239, 2022
7D4D
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BU of 7d4d by Molmil
Structure of L-lysine oxidase precursor in complex with L-lysine (1.24M)
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, L-Lysine alpha-oxidase, LYSINE
著者Kitagawa, M, Ito, N, Matsumoto, Y, Inagaki, K, Imada, K.
登録日2020-09-23
公開日2021-02-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structural basis of enzyme activity regulation by the propeptide of l-lysine alpha-oxidase precursor from Trichoderma viride .
J Struct Biol X, 5, 2021
6RLE
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BU of 6rle by Molmil
Crystal structure of human monoamine oxidase B in complex with styrylpiperidine analogue 97
分子名称: 4-[2-(4-propan-2-ylphenyl)ethyl]-1-[(~{E})-prop-1-enyl]piperidine, Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Iacovino, L.G, Knez, D, Colettis, N, Sova, M, Pislar, A, Higgs, J, Kamecki, F, Mangialavori, I, Dolsak, A, Zakelj, S, Trontelj, J, Kos, J, Marder, N.M, Gobec, S, Binda, C.
登録日2019-05-02
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Stereoselective Activity of 1-Propargyl-4-styrylpiperidine-like Analogues That Can Discriminate between Monoamine Oxidase Isoforms A and B.
J.Med.Chem., 63, 2020
1OJ9
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HUMAN MONOAMINE OXIDASE B IN COMPLEX WITH 1,4-DIPHENYL-2-BUTENE
分子名称: 1,4-DIPHENYL-2-BUTENE, AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE
著者Binda, C, Edmondson, D.E, Mattevi, A.
登録日2003-07-08
公開日2003-08-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insights Into the Mode of Inhibition of Human Mitochondrial Monoamine Oxidase B from High-Resolution Crystal Structures
Proc.Natl.Acad.Sci.USA, 100, 2003
7C3I
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BU of 7c3i by Molmil
Structure of L-lysine oxidase D212A/D315A
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Kitagawa, M, Matsumoto, Y, Inagaki, K, Imada, K.
登録日2020-05-12
公開日2020-09-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of strict substrate recognition of l-lysine alpha-oxidase from Trichoderma viride.
Protein Sci., 29, 2020
2IVD
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BU of 2ivd by Molmil
Structure of protoporphyrinogen oxidase from Myxococcus xanthus with acifluorfen
分子名称: (3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL LAURATE, 5-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-2-NITROBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Corradi, H.R, Corrigall, A.V, Boix, E, Mohan, C.G, Sturrock, E.D, Meissner, P.N, Acharya, K.R.
登録日2006-06-12
公開日2006-10-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Protoporphyrinogen Oxidase from Myxococcus Xanthus and its Complex with the Inhibitor Acifluorfen.
J.Biol.Chem., 281, 2006
6RKB
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BU of 6rkb by Molmil
Crystal structure of human monoamine oxidase B in complex with styrylpiperidine analogue 1
分子名称: 4-[(~{E})-2-(4-fluorophenyl)ethenyl]-1-[(~{E})-prop-1-enyl]piperidine, Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Iacovino, L.G, Knez, D, Colettis, N, Sova, M, Pislar, A, Higgs, J, Kamecki, F, Mangialavori, I, Dolsak, A, Zakelj, S, Trontelj, J, Kos, J, Marder, N.M, Gobec, S, Binda, C.
登録日2019-04-30
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Stereoselective Activity of 1-Propargyl-4-styrylpiperidine-like Analogues That Can Discriminate between Monoamine Oxidase Isoforms A and B.
J.Med.Chem., 63, 2020
5TS5
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BU of 5ts5 by Molmil
Crystal structure of L-amino acid oxidase from Bothrops atrox
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Amine oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Feliciano, P.R, Nonato, M.C.
登録日2016-10-27
公開日2017-04-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure and molecular dynamics studies of L-amino acid oxidase from Bothrops atrox.
Toxicon, 128, 2017
7P4F
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BU of 7p4f by Molmil
Crystal Structure of Monoamine Oxidase B in complex with inhibitor 1
分子名称: 4-(hydroxymethyl)-7-[[4-[[methyl-(phenylmethyl)amino]methyl]phenyl]methoxy]chromen-2-one, Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Iacovino, L.G, Binda, C, Pisani, L.
登録日2021-07-11
公開日2022-05-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures.
Acs Med.Chem.Lett., 13, 2022
1YY5
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BU of 1yy5 by Molmil
Crystal structure of Fms1, a polyamine oxidase from Yeast
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, FMS1 protein
著者Huang, Q, Liu, Q, Hao, Q.
登録日2005-02-23
公開日2005-03-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Fms1 and its Complex with Spermine Reveal Substrate Specificity.
J.Mol.Biol., 348, 2005
2VZ2
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BU of 2vz2 by Molmil
Human MAO B in complex with mofegiline
分子名称: (1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE, AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Bonivento, D, Mattevi, A.
登録日2008-07-29
公開日2008-12-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B.
J. Med. Chem., 51, 2008
5YB8
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BU of 5yb8 by Molmil
L-Amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813 - L-arginine complex
分子名称: ARGININE, FLAVIN-ADENINE DINUCLEOTIDE, L-amino acid oxidase/monooxygenase
著者Im, D, Matsui, D, Arakawa, T, Isobe, K, Asano, Y, Fushinobu, S.
登録日2017-09-03
公開日2018-02-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ligand complex structures of l-amino acid oxidase/monooxygenase from
FEBS Open Bio, 8, 2018
2YG4
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BU of 2yg4 by Molmil
Structure-based redesign of cofactor binding in Putrescine Oxidase: wild type bound to Putrescine
分子名称: 4-HYDROXYBUTAN-1-AMINIUM, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Kopacz, M.M, Rovida, S, van Duijn, E, Fraaije, M.W, Mattevi, A.
登録日2011-04-11
公開日2011-05-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-Based Redesign of Cofactor Binding in Putrescine Oxidase.
Biochemistry, 50, 2011
7B0V
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BU of 7b0v by Molmil
Crystal Structure of human monoamine oxidase B in complex with (E)-3-phenyl-1-(3-(trifluoromethyl)phenyl)prop-2-en-1-one
分子名称: (E)-3-phenyl-1-(3-(trifluoromethyl)phenyl)prop-2-en-1-one, Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Iacovino, L.G, Binda, C.
登録日2020-11-23
公開日2021-11-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Promising Non-cytotoxic Monosubstituted Chalcones to Target Monoamine Oxidase-B.
Acs Med.Chem.Lett., 12, 2021
2VRM
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BU of 2vrm by Molmil
Structure of human MAO B in complex with phenyethylhydrazine
分子名称: AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, PHENYLETHANE
著者Binda, C, Wang, J, Li, M, Hubalek, F, Mattevi, A, Edmondson, D.E.
登録日2008-04-09
公開日2008-04-22
最終更新日2014-01-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Mechanistic Studies of Arylalkylhydrazine Inhibition of Human Monoamine Oxidases a and B
Biochemistry, 47, 2008
2BAC
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BU of 2bac by Molmil
Crystal structure of CLA-producing fatty acid isomerase from P. acnes
分子名称: (11E,13E,15Z)-OCTADECA-11,13,15-TRIENOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
著者Rudolph, M.G, Liavonchanka, A.
登録日2005-10-14
公開日2006-01-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and mechanism of the Propionibacterium acnes polyunsaturated fatty acid isomerase
Proc.Natl.Acad.Sci.Usa, 103, 2006
2DW4
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BU of 2dw4 by Molmil
Crystal structure of human LSD1 at 2.3 A resolution
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1
著者Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-08-02
公開日2007-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25A
Biochem.Biophys.Res.Commun., 366, 2008
3BI2
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BU of 3bi2 by Molmil
Crystal structures of fms1 in complex with its inhibitors
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Polyamine oxidase FMS1, dodecane-1,12-diamine
著者Huang, Q, Hao, Q.
登録日2007-11-29
公開日2008-01-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of fms1 in complex with its inhibitors
To be Published
4GUU
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BU of 4guu by Molmil
Crystal structure of LSD2-NPAC with tranylcypromine
分子名称: Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, ZINC ION, ...
著者Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Xu, Y.
登録日2012-08-29
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
1REO
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BU of 1reo by Molmil
L-amino acid oxidase from Agkistrodon halys pallas
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AHPLAAO, CITRIC ACID, ...
著者Zhang, H, Teng, M, Niu, L, Wang, Y, Wang, Y, Liu, Q, Huang, Q, Hao, Q, Dong, Y, Liu, P.
登録日2003-11-07
公開日2004-05-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Purification, partial characterization, crystallization and structural determination of AHP-LAAO, a novel L-amino-acid oxidase with cell apoptosis-inducing activity from Agkistrodon halys pallas venom.
Acta Crystallogr.,Sect.D, 60, 2004
7KHN
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BU of 7khn by Molmil
NicA2 variant N462Y/W427Y in complex with (S)-nicotine
分子名称: (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, Amine oxidase, FLAVIN-ADENINE DINUCLEOTIDE
著者Tararina, M.A, Allen, K.N.
登録日2020-10-21
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Fast Kinetics Reveals Rate-Limiting Oxidation and the Role of the Aromatic Cage in the Mechanism of the Nicotine-Degrading Enzyme NicA2.
Biochemistry, 60, 2021
6KGR
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BU of 6kgr by Molmil
LSD1-FCPA-MPE N5 adduct model
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-[4-[5-fluoranyl-2-(trifluoromethyl)phenyl]phenyl]propanal, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Niwa, H, Sato, S, Handa, N, Umehara, T.
登録日2019-07-12
公開日2020-03-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Development and Structural Evaluation of N-Alkylated trans-2-Phenylcyclopropylamine-Based LSD1 Inhibitors.
Chemmedchem, 15, 2020
6KGQ
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BU of 6kgq by Molmil
LSD1-FCPA-MPE five-membered ring adduct model
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-[4-[5-fluoranyl-2-(trifluoromethyl)phenyl]phenyl]propanal, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Niwa, H, Sato, S, Handa, N, Umehara, T.
登録日2019-07-12
公開日2020-03-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Development and Structural Evaluation of N-Alkylated trans-2-Phenylcyclopropylamine-Based LSD1 Inhibitors.
Chemmedchem, 15, 2020
4DGK
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Crystal structure of Phytoene desaturase CRTI from Pantoea ananatis
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Phytoene dehydrogenase
著者Schaub, P, Yu, Q, Gemmecker, S, Poussin-Courmontagne, P, Mailliot, J, McEwen, A.G, Ghisla, S, Beyer, P, Cavarelli, J.
登録日2012-01-26
公開日2012-10-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献On the structure and function of the phytoene desaturase CRTI from Pantoea ananatis, a membrane-peripheral and FAD-dependent oxidase/isomerase.
Plos One, 7, 2012
5G3U
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BU of 5g3u by Molmil
The structure of the L-tryptophan oxidase VioA from Chromobacterium violaceum in complex with its inhibitor 2-(1H-indol-3-ylmethyl)prop-2- enoic acid
分子名称: 2-[(1H-indol-3-yl)methyl]prop-2-enoic acid, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Krausze, J, Rabe, J, Moser, J.
登録日2016-05-01
公開日2016-08-03
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.377 Å)
主引用文献Biosynthesis of Violacein, Structure and Function of l-Tryptophan Oxidase VioA from Chromobacterium violaceum.
J.Biol.Chem., 291, 2016

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