PDB: 163 件ウェブページステータス検索Chemie searchBIRD

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1ME7	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with RVP and MOA bound 分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, MYCOPHENOLIC ACID, POTASSIUM ION, ... 著者 Prosise, G.L, Wu, J, Luecke, H. 登録日 2002-08-08 公開日 2003-01-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structure of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with the Inhibitor Ribavirin Monophosphate Reveals a Catalysis-dependent Ion-binding Site J.Biol.Chem., 277, 2002
1NFB	Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with 6Cl-IMP and NAD 分子名称: 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, Inosine-5'-monophosphate dehydrogenase 2, ... 著者 Risal, D, Strickler, M.D, Goldstein, B.M. 登録日 2002-12-13 公開日 2004-01-27 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The Conformation of NAD Bound to Human Inosine Monophosphate Dehydrogenase Type II To be Published
1MEH	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with IMP and MOA bound 分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID, MYCOPHENOLIC ACID, ... 著者 Prosise, G.L, Luecke, H. 登録日 2002-08-08 公開日 2003-08-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism J.Mol.Biol., 326, 2003
1MEI	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with XMP and mycophenolic acid bound 分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, MYCOPHENOLIC ACID, POTASSIUM ION, ... 著者 Prosise, G.L, Luecke, H. 登録日 2002-08-08 公開日 2003-08-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism J.Mol.Biol., 326, 2003
1ME8	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with RVP bound 分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, POTASSIUM ION, RIBAVIRIN MONOPHOSPHATE, ... 著者 Prosise, G.L, Wu, J, Luecke, H. 登録日 2002-08-08 公開日 2003-01-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with the Inhibitor Ribavirin Monophosphate Reveals a Catalysis-dependent Ion-binding Site J.Biol.Chem., 277, 2002
4Z87	Structure of the IMP dehydrogenase from Ashbya gossypii bound to GDP 分子名称: ACETATE ION, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, ... 著者 Buey, R.M, de Pereda, J.M, Revuelta, J.L. 登録日 2015-04-08 公開日 2015-11-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases. Nat Commun, 6, 2015
6U8N	Human IMPDH2 treated with ATP, IMP, and NAD+. Fully extended filament segment reconstruction. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, ... 著者 Johnson, M.C, Kollman, J.M. 登録日 2019-09-05 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.29 Å) 主引用文献 Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6U8E	Human IMPDH2 treated with ATP, IMP, and NAD+. Filament assembly interface reconstruction. 分子名称: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Johnson, M.C, Kollman, J.M. 登録日 2019-09-04 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.03 Å) 主引用文献 Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6UDQ	Human IMPDH2 treated with ATP, IMP, and 20 mM GTP. Fully compressed filament end reconstruction. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... 著者 Johnson, M.C, Kollman, J.M. 登録日 2019-09-19 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6UDO	Human IMPDH2 treated with ATP, IMP, and 20 mM GTP. Fully compressed filament segment reconstruction. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... 著者 Johnson, M.C, Kollman, J.M. 登録日 2019-09-19 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6UDP	Human IMPDH2 treated with ATP, IMP, and 20 mM GTP. Filament assembly interface reconstruction. 分子名称: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2 著者 Johnson, M.C, Kollman, J.M. 登録日 2019-09-19 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6UA4	Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Bent (3/4 compressed, 1/4 extended) segment reconstruction. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... 著者 Johnson, M.C, Kollman, J.M. 登録日 2019-09-10 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.65 Å) 主引用文献 Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6U8R	Human IMPDH2 treated with ATP, IMP, and NAD+. Bent (1/4 compressed, 3/4 extended) segment reconstruction. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, ... 著者 Johnson, M.C, Kollman, J.M. 登録日 2019-09-05 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6U9O	Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Fully compressed filament segment reconstruction. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... 著者 Johnson, M.C, Kollman, J.M. 登録日 2019-09-09 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.36 Å) 主引用文献 Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6UA5	Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Free interfacial octamer reconstruction. 分子名称: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Johnson, M.C, Kollman, J.M. 登録日 2019-09-10 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.79 Å) 主引用文献 Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6U8S	Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Filament assembly interface reconstruction. 分子名称: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Johnson, M.C, Kollman, J.M. 登録日 2019-09-05 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6UAJ	Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Free canonical octamer reconstruction. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... 著者 Johnson, M.C, Kollman, J.M. 登録日 2019-09-10 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.84 Å) 主引用文献 Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6UC2	Human IMPDH2 treated with ATP and 2 mM GTP. Free canonical octamer reconstruction. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase 2 著者 Johnson, M.C, Kollman, J.M. 登録日 2019-09-13 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.48 Å) 主引用文献 Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
6UA2	Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Bent (2/4 compressed, 2/4 extended) segment reconstruction. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... 著者 Johnson, M.C, Kollman, J.M. 登録日 2019-09-10 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
5TC3	Structure of IMP dehydrogenase from Ashbya gossypii bound to ATP and GDP 分子名称: ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Fernandez-Justel, D, de Pereda, J.M, Revuelta, J.L, Buey, R.M. 登録日 2016-09-14 公開日 2017-06-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.462 Å) 主引用文献 A nucleotide-controlled conformational switch modulates the activity of eukaryotic IMP dehydrogenases. Sci Rep, 7, 2017
7PMZ	Crystal structure of Streptomyces coelicolor guaB (IMP dehydrogenase) bound to ATP and ppGpp at 2.0 A resolution 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5',3'-TETRAPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, ... 著者 Fernandez-Justel, D, Revuelta, J.L, Buey, R.M. 登録日 2021-09-04 公開日 2022-05-11 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Diversity of mechanisms to control bacterial GTP homeostasis by the mutually exclusive binding of adenine and guanine nucleotides to IMP dehydrogenase. Protein Sci., 31, 2022
7PJI	Crystal structure of Pseudomonas aeruginosa guaB (IMP dehydrogenase) bound to ATP and GDP at 1.65A resolution 分子名称: ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Fernandez-Justel, D, Buey, R.M. 登録日 2021-08-24 公開日 2022-07-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Diversity of mechanisms to control bacterial GTP homeostasis by the mutually exclusive binding of adenine and guanine nucleotides to IMP dehydrogenase. Protein Sci., 31, 2022
7QBJ	bacterial IMPDH chimera 分子名称: Inosine-5'-monophosphate dehydrogenase 著者 Labesse, G, Gelin, M, Munier-Lehmann, H, Gedeon, A, Haouz, A. 登録日 2021-11-19 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases. Protein Sci., 32, 2023
7QEM	bacterial IMPDH chimera 分子名称: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 著者 Labesse, G, Gelin, M, Gedeon, A, Haouz, A, Munier-Lehmann, H. 登録日 2021-12-03 公開日 2023-06-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases. Protein Sci., 32, 2023
7QDX	bacterial IMPDH chimera 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, MAGNESIUM ION 著者 Labesse, G, Gelin, M, Munier-Lehmann, H, Gedeon, A, Haouz, A. 登録日 2021-11-30 公開日 2023-06-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases. Protein Sci., 32, 2023

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